Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Réplication de l'ADN"'
Autor:
Sharma, Jyoti
Les gènes de l'isocitrate déshydrogénase (IDH) sont mutés dans 70 à 80 % des gliomes de bas grade. Les enzymes mutantes IDH qui en résultent présentent une activité de gain de fonction, produisant du R-2-hydroxyglutarate (R-2-HG), appelé onc
Externí odkaz:
http://hdl.handle.net/1866/32261
Autor:
Gopinathan Nair, Amogh
Chez les cellules humaines, environ 2 mètres d'ADN est compacté dans le noyau cellulaire par la formation d'une structure nucléoprotéique appelée chromatine. La chromatine est composée d'ADN enroulé à la surface d'un octamère de core histone
Externí odkaz:
http://hdl.handle.net/1866/26304
Autor:
Benslimane, Yahya
Le matériel génétique (l’ADN) d’un organisme contient l’information nécessaire à sa survie, sa croissance et sa reproduction. La perte de cette information affecte grandement la santé de l’organisme et cette altération est l’u
Externí odkaz:
http://hdl.handle.net/1866/25540
Publikováno v:
Molecular Cell
Molecular Cell, 2022, 82 (10), pp.1909-1923.e5. ⟨10.1016/j.molcel.2022.03.017⟩
Molecular Cell, 2022, 82 (10), pp.1909-1923.e5. ⟨10.1016/j.molcel.2022.03.017⟩
International audience; The lack of a consensus DNA sequence defining replication origins in mammals has led researchers to consider chromatin as a means to specify these regions. However, to date, there is no mechanistic understanding of how this co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62d13429596df2eec9180a5176404b9
https://doi.org/10.1016/j.molcel.2022.03.017
https://doi.org/10.1016/j.molcel.2022.03.017
Autor:
Iuliani, Ilaria
Despite over 50 years of study, key questions on the bacterial cell cycle remain unanswered. In particular, the debate is open concerning the regulation of DNA replication initiation in E. coli and its role in the dynamics of cell growth and division
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______166::e29724b3b06b48586e34d6f9a9210b03
https://theses.hal.science/tel-03793341
https://theses.hal.science/tel-03793341
Autor:
Cahn, Alice
Publikováno v:
Biochimie, Biologie Moléculaire. Université Paris-Saclay, 2020. Français. ⟨NNT : 2020UPASL061⟩
Complete and accurate DNA replication is crucial to transfer correct genetic information to the daughter cells. Various obstacles can interfere with the progression of the replication machinery, threatening genome integrity. Specialized error-prone t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ab9cb5330eaf10dffbfdb0c414636bc9
https://tel.archives-ouvertes.fr/tel-03494316/file/78936_CAHN_2020_archivage.pdf
https://tel.archives-ouvertes.fr/tel-03494316/file/78936_CAHN_2020_archivage.pdf
Autor:
Al Ahmad Nachar, Baraah
Publikováno v:
Agricultural sciences. Université Montpellier, 2020. English. ⟨NNT : 2020MONTT028⟩
Why solid tumours show high chromosome instability is still poorly understood. Seminal work in the host lab has shown in the yeast model system that precocious CDK activation and reduced origin licensing in G1 cause S-phase extension and chromosome r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______212::7c30b7a2e86fff946c45aab0ff675e97
https://tel.archives-ouvertes.fr/tel-03155270/file/2020_AL_AHMAD_NACHAR_archivage.pdf
https://tel.archives-ouvertes.fr/tel-03155270/file/2020_AL_AHMAD_NACHAR_archivage.pdf
Autor:
Meléndez García, Rodrigo
Publikováno v:
Molecular biology. Université Paris-Saclay, 2020. English. ⟨NNT : 2020UPASL014⟩
Stemness could be defined as a state in which a cell is able to self-renew and/or to differentiate after cell division. Before this happens, exhaustive duplication of the genome free of errors must occur in order to avoid deleterious mutations, a hal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::730a304e72b88b16b886d3be22a76581
https://tel.archives-ouvertes.fr/tel-02989691
https://tel.archives-ouvertes.fr/tel-02989691
Autor:
Abderahmane, Nina Farida
Publikováno v:
Biologie cellulaire. Université Grenoble Alpes [2020-..], 2020. Français. ⟨NNT : 2020GRALV022⟩
Preserving the integrity of genetic material is crucial to ensure cell survival and prevent tumor development. RNA Interference (RNAi) plays an important role in this context. This conserved process is well known to mediate sequence-specific transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::0f91ee7925ccb4e02e7ca820d9ef921a
https://theses.hal.science/tel-03704776/document
https://theses.hal.science/tel-03704776/document
Autor:
Ben Yamin Rosen, Barbara
DNA replication is a fundamental process that ensures accurate duplication of the genetic information. Various perturbations can impede replication fork progression, and thus threatening genome integrity. To prevent fork collapse, replicative DNA pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______166::4481d2cf13190c5922081ce368fa1867
https://theses.hal.science/tel-03868263
https://theses.hal.science/tel-03868263