Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Réparation de l'ADN"'
Autor:
Rouleau-Turcotte, Elise
L’ADN contient l’information génétique essentielle au développement et au bon fonctionnement de tout organisme vivant. Cependant, l’ADN peut être endommagé ou modifié par une exposition régulière à différents facteurs tels que la lumi
Autor:
Aubé, Fabien
Publikováno v:
Biologie cellulaire. Ecole normale supérieure de lyon-ENS LYON, 2022. Français. ⟨NNT : 2022ENSL0061⟩
According to the commonly used metaphor of "genetic programs", cells adapt to environmental fluctuations through more or less complex signalling pathways pre-programmed in their genomes, leading to a compartmentalized description of cellular activiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ef29ad0b100ce1665902d072592e0720
https://theses.hal.science/tel-03935442/document
https://theses.hal.science/tel-03935442/document
Publikováno v:
Biophysique. Université de Rennes, 2022. Français. ⟨NNT : 2022REN1B060⟩
DNA is constantly subjected to various stress, threatening its integrity, and consequently, the proper functioning of the cell. In order to preserve the genomic integrity, the cell can activate a large set of repair pathways. One of the most common g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2755::76981daf6f7758e573523e3625688746
https://theses.hal.science/tel-04096380/file/D_AUGUSTIN_DE_BOURGUISSON_Ostiane.pdf
https://theses.hal.science/tel-04096380/file/D_AUGUSTIN_DE_BOURGUISSON_Ostiane.pdf
Autor:
Cahuzac, Maxime
Le cancer de la prostate (CP) est le cancer le plus diagnostiqué chez les hommes en Amérique du Nord. Même si les méthodes de détection et les traitements s’améliorent au fil des années, le phénomène de résistance reste encore un problèm
Publikováno v:
Plants genetics. Université Clermont Auvergne, 2022. English. ⟨NNT : 2022UCFAC023⟩
Meiosis, a specialized cell division of the germ cells, is the chromosomal foundation of sexual reproduction in eukaryote organisms. At the outset of meiosis, a programmed induction of double-strand breaks (DSBs) initiates an intricate and highly reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2885::7487ce7ea5c5616cc6b0de40c2b544f1
https://theses.hal.science/tel-03943077/file/2022UCFAC023_HERNANDEZ_SANCHEZ_REBATO.pdf
https://theses.hal.science/tel-03943077/file/2022UCFAC023_HERNANDEZ_SANCHEZ_REBATO.pdf
Autor:
Brunet, Manon
Publikováno v:
Cancer. Université Paul Sabatier-Toulouse III, 2021. Français. ⟨NNT : 2021TOU30090⟩
The poor prognosis of pancreatic cancer (PC) is explained by a late diagnosis and lack of efficient treatments. A better understanding of the molecular mechanisms that govern its initiation, progression and resistance to most chemotherapies is essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::400e144f9bb9da2498ab0cb3ae3d87f9
https://theses.hal.science/tel-03587339/document
https://theses.hal.science/tel-03587339/document
Autor:
Fayyad, Nour
Publikováno v:
Cancer. Université Grenoble Alpes [2020-..], 2021. English. ⟨NNT : 2021GRALS016⟩
Xeroderma pigmentosum C (XPC) protein initiates global genome-nucleotide excision repair (GG-NER) to remove UV-induced helix-distorting DNA lesions such as pyrimidine (6-4) pyrimidone photoproducts [(6-4) PPs] and cyclobutane pyrimidine dimers (CPDs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d106dc46544ea429086ceaa4e96ee98b
https://tel.archives-ouvertes.fr/tel-03405199/file/FAYYAD_2021_archivage.pdf
https://tel.archives-ouvertes.fr/tel-03405199/file/FAYYAD_2021_archivage.pdf
Autor:
Sall, Fatimata Bintou
Publikováno v:
Biochimie, Biologie Moléculaire. Université Paris-Saclay; Université Cheikh Anta Diop (Dakar), 2021. Français. ⟨NNT : 2021UPASL034⟩
Burkitt's lymphoma is a B cell non-Hodgkin's lymphoma characterized in 80% of cases by a chromosomal translocation involving the MYC oncogene on chromosome 8 and the immunoglobulin heavy chain gene IGH on chromosome 14. The development of this lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b2dd0131c240036bf8990c402a2cedf
https://tel.archives-ouvertes.fr/tel-03275207
https://tel.archives-ouvertes.fr/tel-03275207
Autor:
Muhammad, Ali-Akbar
Publikováno v:
Biochimie, Biologie Moléculaire. Université Paris-Saclay, 2021. Français. ⟨NNT : 2021UPASL031⟩
Homologous recombination (HR) is a major pathway for repairing DSB, it intervenes during replication, in the recovery of stalled and collapsed replication forks. The mechanism of HR is based on a genetic exchange using a homologous sequence as a temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d6e2af4780406f0f23bfede9f6ce41d6
https://theses.hal.science/tel-03656075
https://theses.hal.science/tel-03656075
Autor:
Dorison, Hugo
The repair of double-stranded DNA breaks (DSBs) by homologous recombination involves the formation of branched intermediates that can lead to crossovers following nucleolytic resolution. Ubiquitin and SUMO modification is commonplace amongst the DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______166::6b1f0fcc5fdfca23a87e2616fb6cc2ea
https://theses.hal.science/tel-03539739
https://theses.hal.science/tel-03539739