Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Réna G. Deschesnes"'
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 3 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbe591730b8b2441ad72c114d464028
https://doi.org/10.1158/0008-5472.22370597
https://doi.org/10.1158/0008-5472.22370597
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Chloroethylureas (CEU) are soft alkylating agents that covalently bind to β-tubulin (βTAC) and affect microtubule polymerization dynamics. Herein, we report the identification of a CEU subset and its corresponding oxazolines, which induce cell grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712ac88f4e645fec73ddb078788e182a
https://doi.org/10.1158/0008-5472.c.6496454
https://doi.org/10.1158/0008-5472.c.6496454
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 2 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414fcc3f61b66dc729c6505b5d14030e
https://doi.org/10.1158/0008-5472.22370603.v1
https://doi.org/10.1158/0008-5472.22370603.v1
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 1 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac292b03d61b7d2be359707c2792261f
https://doi.org/10.1158/0008-5472.22370606.v1
https://doi.org/10.1158/0008-5472.22370606.v1
Autor:
Nicolas Bertrand, Geneviève Garon, Michel Houde, Timothy J. Holzer, Guillaume Beaudry, Jean-François Haince, Réna G. Deschesnes, Martin Beaulieu, Marie Desaulniers
Publikováno v:
Diagnostic Molecular Pathology. 19:20-27
Up to 30% of patients with stage II (pN0) colon cancer develop recurrences, suggesting that the presence of lymph node (LN) metastases escaped detection at histopathologic staging. A simple way to overcome this limitation and to improve staging accur
Autor:
Emmanuelle Mounetou, Eric Petitclerc, Jacques Lacroix, Richard Janvier, Claude Marquis, Jean Legault, René C.-Gaudreault, Jean-Claude Madelmont, Elisabeth Miot-Noirault, Marie-France Côté, Réna G. Deschesnes
Publikováno v:
Cancer Research. 64:4654-4663
The development of new anticancer agents with lower toxicity, higher therapeutic index, and weaker tendency to induce resistant phenotypes in tumor cells is a continuous challenge for the scientific community. Toward that end, we showed previously th
Autor:
Simon Rousseau, François Houle, Girish M. Shah, Jacques Landry, Réna G. Deschesnes, Jacques Huot
Publikováno v:
The Journal of Cell Biology
In endothelial cells, H2O2 induces the rapid formation of focal adhesion complexes at the ventral face of the cells and a major reorganization of the actin cytoskeleton into dense transcytoplasmic stress fibers. This change in actin dynamics results
Autor:
René C.-Gaudreault, Jacques Lacroix, Jean L.C. Rousseau, Eric Petitclerc, Réna G. Deschesnes, Alexandre Patenaude, Marie-France Côté
Publikováno v:
Cancer research. 67(5)
Chloroethylureas (CEU) are soft alkylating agents that covalently bind to β-tubulin (βTAC) and affect microtubule polymerization dynamics. Herein, we report the identification of a CEU subset and its corresponding oxazolines, which induce cell grow
Autor:
Eric Petitclerc, Jessica S. Fortin, Jean L.C. Rousseau, Christine Ricard, Réna G. Deschesnes, René C.-Gaudreault, Marie-France Côté, Alexandre Patenaude, Jacques Huot
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 320(2)
Microtubule disruption provokes cytoskeleton and cell adhesion changes whose importance for apoptosis induction remains unclear. The present study focuses on the functional and the molecular adhesion kinetics that are induced by microtubule disruptio
Autor:
Eric, Petitclerc, Réna G, Deschesnes, Marie-France, Côté, Claude, Marquis, Richard, Janvier, Jacques, Lacroix, Elisabeth, Miot-Noirault, Jean, Legault, Emmanuelle, Mounetou, Jean-Claude, Madelmont, René, C -Gaudreault
Publikováno v:
Cancer research. 64(13)
The development of new anticancer agents with lower toxicity, higher therapeutic index, and weaker tendency to induce resistant phenotypes in tumor cells is a continuous challenge for the scientific community. Toward that end, we showed previously th