Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Rémy Pedeux"'
Autor:
Katherine Yaacoub, Rémy Pedeux, Pierre Lafite, Ulrich Jarry, Samia Aci-Sèche, Pascal Bonnet, Richard Daniellou, Thierry Guillaudeux
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 710-728 (2024)
The catalytically inactive caspase-8-homologous protein, c-FLIP, is a potent antiapoptotic protein highly expressed in various types of cancers. c-FLIP competes with caspase-8 for binding to the adaptor protein FADD (Fas-Associated Death Domain) foll
Externí odkaz:
https://doaj.org/article/82011d2e6c2d4f4590fabc6ed3080eb7
Autor:
Ulrich Jarry, Megane Bostoen, Jérome Archambeau, Raphaël Pineau, Laura Chaillot, Florence Jouan, Hélène Solhi, Hugo Ferrari, Rémy Le Guevel, Valentine Mennessier, Hervé Lena, Romain Corre, Charles Ricordel, Thierry Guillaudeux, Rémy Pedeux
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304914 (2024)
Lung cancer is one of the most common and deadliest cancers. Preclinical models are essential to study new therapies and combinations taking tumor genetics into account. We have established cell lines expressing the luciferase gene from lines with va
Externí odkaz:
https://doaj.org/article/b617489982e245cfb967617c5f9cdb27
Autor:
Charles Ricordel, L. Chaillot, E. I. Vlachavas, M. Logotheti, A. Jouannic, T. Desvallees, G. Lecuyer, M. Aubry, G. Kontogianni, C. Mastrokalou, F. Jouan, U. Jarry, R. Corre, Y. Le Guen, T. Guillaudeux, H. Lena, A. Chatziioannou, Rémy Pedeux
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Circulating tumor cells (CTC) have been studied in various solid tumors but clinical utility of CTC in small cell lung cancer (SCLC) remains unclear. The aim of the CTC-CPC study was to develop an EpCAM-independent CTC isolation method allow
Externí odkaz:
https://doaj.org/article/4b75c5522d4840d086fb8b6d2e90e3ed
Autor:
Ulrich Jarry, Mégane Bostoën, Raphaël Pineau, Laura Chaillot, Valentine Mennessier, Pierre Montagne, Emilie Motte, Marjorie Gournay, Arnaud Le Goff, Thierry Guillaudeux, Rémy Pedeux
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Osimertinib is a third generation tyrosine kinase inhibitor (TKI) that targets the epidermal growth factor receptor (EGFR) in lung cancer. However, although this molecule is not subject to some of the resistance mechanisms observe
Externí odkaz:
https://doaj.org/article/f2c636e86e39410087fb7567f715cd88
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are currently recommended as first-line treatment for advanced non-small-cell lung cancer (NSCLC) with EGFR-activating mutations. Third-generation (3rd G) EGFR-TKIs, including
Externí odkaz:
https://doaj.org/article/c4e8aa0f3f654af4bc84608754228119
Autor:
Estefanie Dufey, José Manuel Bravo-San Pedro, Cristian Eggers, Matías González-Quiroz, Hery Urra, Alfredo I. Sagredo, Denisse Sepulveda, Philippe Pihán, Amado Carreras-Sureda, Younis Hazari, Eduardo A. Sagredo, Daniela Gutierrez, Cristian Valls, Alexandra Papaioannou, Diego Acosta-Alvear, Gisela Campos, Pedro M. Domingos, Rémy Pedeux, Eric Chevet, Alejandra Alvarez, Patricio Godoy, Peter Walter, Alvaro Glavic, Guido Kroemer, Claudio Hetz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
IRE1α plays a key role in the unfolded protein response (UPR) by promoting the unconventional splicing of the XBP1 and the selective cleavage of RNAs. Here the authors report that IRE1α is activated upon the DNA damage response and selectively cont
Externí odkaz:
https://doaj.org/article/41bd77e35d0d4d3fba7541fc5ffc6412
Autor:
Ulrich Jarry, Mégane Bostoën, Raphaël Pineau, Laura Chaillot, Valentine Mennessier, Pierre Montagne, Emilie Motte, Marjorie Gournay, Arnaud Le Goff, Thierry Guillaudeux, Rémy Pedeux
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/e526c84836b14c64b3110305e75ef4d9
Autor:
Thi-Bach-Le Nguyen, Olivier Delalande, Isabelle Rouaud, Solenn Ferron, Laura Chaillot, Rémy Pedeux, Sophie Tomasi
Publikováno v:
Molecules, Vol 23, Iss 8, p 1951 (2018)
Two compounds (1) and (2) containing tert-butylphenol groups were, for the first time, produced during the culture of Paenibacillus odorifer, a bacterial strain associated with the crustose lichen, Rhizocarpon geographicum. Their entire structures we
Externí odkaz:
https://doaj.org/article/a54d1c81d69f4d889fdf4f3e673d540d
Autor:
Rémy Pedeux, Curtis C. Harris, Manuel Serrano, Christian Brambilla, Elisabeth Brambilla, Claire Fonti, Delphine Larrieu, Manuel Collado, Ana I. Robles, Damien Ythier, Romuald Binet
Supplementary Table 2 from WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115b9ce59edd54a1afc88a0574f4c859
https://doi.org/10.1158/0008-5472.22380888.v1
https://doi.org/10.1158/0008-5472.22380888.v1
Autor:
Rémy Pedeux, Curtis C. Harris, Manuel Serrano, Christian Brambilla, Elisabeth Brambilla, Claire Fonti, Delphine Larrieu, Manuel Collado, Ana I. Robles, Damien Ythier, Romuald Binet
Senescence is a tumor suppression mechanism that is induced by several stimuli, including oncogenic signaling and telomere shortening, and controlled by the p53/p21WAF1 signaling pathway. Recently, a critical role for secreted factors has emerged, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e679ea526640bd03180fa0e557bdc17
https://doi.org/10.1158/0008-5472.c.6499701.v1
https://doi.org/10.1158/0008-5472.c.6499701.v1