Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rémy Gebleux"'
Autor:
Lucia D’Amico, Ulrike Menzel, Michael Prummer, Philipp Müller, Mélanie Buchi, Abhishek Kashyap, Ulrike Haessler, Alexander Yermanos, Rémy Gébleux, Manfred Briendl, Tamara Hell, Fabian I. Wolter, Roger R. Beerli, Iva Truxova, Špíšek Radek, Tatjana Vlajnic, Ulf Grawunder, Sai Reddy, Alfred Zippelius
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Increasing evidence suggests that antibody-drug conjugates (ADCs) can enhance anti-tumor immunity and improve clinical outcome. Here, we elucidate the therapeutic efficacy and immune-mediated mechanisms of a novel HER2-targeting ADC bearing
Externí odkaz:
https://doaj.org/article/fc1ae255093f4779af3f20d721a4f07a
Autor:
Roger R. Beerli, Salvatore Di Girolamo, Ulf Grawunder, Tamara Hell, Chasper Puorger, Mara Castiglione, Manfred Briendl, Georg Lipps, Rémy Gebleux, Maren Vogel
Publikováno v:
Biochemical Journal. 476:665-682
Sortase enzymes play an important role in Gram-positive bacteria. They are responsible for the covalent attachment of proteins to the surface of the bacteria and perform this task via a highly sequence-specific transpeptidation reaction. Since these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf820e17f4bf494f1d274e038b5a8d46
https://doi.org/10.1042/bcj20180885
https://doi.org/10.1042/bcj20180885
Autor:
Roger R. Beerli, Špíšek Radek, Alexander Yermanos, Ulrike Menzel, Rémy Gebleux, Manfred Briendl, Fabian I. Wolter, Lucia D'Amico, Melanie Buchi, Sai T. Reddy, Philipp Müller, Ulrike Haessler, Iva Truxova, Alfred Zippelius, Abhishek S. Kashyap, Tatjana Vlajnic, Tamara Hell, Ulf Grawunder, Michael Prummer
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 7 (1)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Journal for ImmunoTherapy of Cancer, 7 (1)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Increasing evidence suggests that antibody-drug conjugates (ADCs) can enhance anti-tumor immunity and improve clinical outcome. Here, we elucidate the therapeutic efficacy and immune-mediated mechanisms of a novel HER2-targeting ADC bearing a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170de8c3b66613b002185d24a48e18de
http://europepmc.org/articles/PMC6341578
http://europepmc.org/articles/PMC6341578
Autor:
Rémy Gebleux, Ina Hellmann, Funda Meric-Bernstam, Ulf Grawunder, Meredith McKean, Roger R. Beerli, Anthony W. Tolcher, Pawel Chrom, Lorenz Waldmeier
Publikováno v:
Journal of Clinical Oncology. 39:TPS1108-TPS1108
TPS1108 Background: The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is highly expressed during embryonic development, but is minimally present or absent on post-partum healthy tissues. ROR1 is expressed in a variety of hematological and so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d4f2cafc65c34ba374a8b939167eaa
https://doi.org/10.1200/jco.2021.39.15_suppl.tps1108
https://doi.org/10.1200/jco.2021.39.15_suppl.tps1108
Autor:
Roger R. Beerli, Yasmin Grether, Philippe F.-X. Corvini, Yves Dudal, Patrick Shahgaldian, M. Rita Correro, Ulf Grawunder, Sophie Braga-Lagache, Federica Richina, Manon L. Briand, Manfred Heller, Rémy Gebleux
Publikováno v:
Chemical Communications
We report the first method of enzyme protection enabling the production of partially shielded enzymes capable of processing substrates as large as proteins. We show that partially shielded sortase retains its transpeptidase activity and can perform b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e404ef429a14fef7e9fbe901be9fda43