Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rémy Denzler"'
Autor:
Flurin Item, Stephan Wueest, Vera Lemos, Sokrates Stein, Fabrizio C. Lucchini, Rémy Denzler, Muriel C. Fisser, Tenagne D. Challa, Eija Pirinen, Youngsoo Kim, Silvio Hemmi, Erich Gulbins, Atan Gross, Lorraine A. O’Reilly, Markus Stoffel, Johan Auwerx, Daniel Konrad
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Hepatic steatosis is a common disease closely associated with metabolic syndrome and insulin resistance. Here Item et al. show that Fas, a member of the TNF receptor superfamily, contributes to mitochondrial dysfunction, steatosis development, and in
Externí odkaz:
https://doaj.org/article/651aa8c22bce4313bef6d51b35cf53ab
Autor:
Johannes Neu, Piotr Jan Dziunycz, Andreas Dzung, Karine Lefort, Martin Falke, Rémy Denzler, Sandra Nicole Freiberger, Guergana Iotzova-Weiss, Aleksandar Kuzmanov, Mitchell Paul Levesque, Gian-Paolo Dotto, Günther Franz L Hofbauer
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185028 (2017)
Cutaneous squamous cell carcinoma (SCC) is the second most common human skin cancer with a rapidly increasing incidence among the Caucasian population. Among the many regulators, responsible for cancer progression and growth, microRNAs (miRNA) are ge
Externí odkaz:
https://doaj.org/article/8983832420534c8bb76f290087eb3d08
Autor:
Lubov Petkova Nedialkova, Rémy Denzler, Martin B Koeppel, Manuel Diehl, Diana Ring, Thorsten Wille, Roman G Gerlach, Bärbel Stecher
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003844 (2014)
The host's immune system plays a key role in modulating growth of pathogens and the intestinal microbiota in the gut. In particular, inflammatory bowel disorders and pathogen infections induce shifts of the resident commensal microbiota which can res
Externí odkaz:
https://doaj.org/article/a975d4d0329e475d9ba9d5a3d63e837b
Autor:
Fabrizio C. Lucchini, Johan Auwerx, Rémy Denzler, Tenagne D. Challa, Eija Pirinen, Daniel Konrad, Stephan Wueest, Atan Gross, Lorraine A. O'Reilly, Youngsoo Kim, Silvio Hemmi, Erich Gulbins, Sokrates Stein, Flurin Item, Muriel C. Fisser, Markus Stoffel, Vera Lemos
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications, 8
Nature Communications
Nature Communications, 8
Nonalcoholic fatty liver disease is one of the most prevalent metabolic disorders and it tightly associates with obesity, type 2 diabetes, and cardiovascular disease. Reduced mitochondrial lipid oxidation contributes to hepatic fatty acid accumulatio
Autor:
Markus Stoffel, Sean E. McGeary, Rémy Denzler, Alexandra C. Title, David P. Bartel, Vikram Agarwal
Publikováno v:
Molecular Cell
Elsevier
Molecular Cell, 64 (3)
Elsevier
Molecular Cell, 64 (3)
Summary Expression changes of competing endogenous RNAs (ceRNAs) have been proposed to influence microRNA (miRNA) activity and thereby regulate other transcripts containing miRNA-binding sites. Here, we find that although miRNA levels define the exte
Autor:
Kashan Ahmed, Felipe Nunez Villena, Rémy Denzler, Domenico Bosco, Martina Spranger, François Pattou, Mathieu Latreille, Ferdinand von Meyenn, Nadiia Kondratiuk, Karolin Herrmanns, Markus Stoffel, Julie Kerr-Conte, Bengt-Frederik Belgardt, Thomas Rülicke
Publikováno v:
Nature medicine
Nature Medicine
Nature Medicine, Vol. 21, No 6 (2015) pp. 619-627
Nature Medicine
Nature Medicine, Vol. 21, No 6 (2015) pp. 619-627
Pancreatic beta cell death is a hallmark of type 1 (T1D) and type 2 (T2D) diabetes, but the molecular mechanisms underlying this aspect of diabetic pathology are poorly understood. Here we report that expression of the microRNA (miR)-200 family is st
Autor:
Mathieu Latreille, Markus Stoffel, Emanuel Gasser, Mary P. LaPierre, Yinjie Yang, Kashan Ahmed, Jukka Kero, Thomas Rülicke, Rémy Denzler
MicroRNAs (miRNAs) are negative modulators of gene expression that fine-tune numerous biological processes. miRNA loss-of-function rarely results in highly penetrant phenotypes, but rather, influences cellular responses to physiologic and pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166ef484bd5a2f3e65b1e0c004c4c3bd
http://hdl.handle.net/10044/1/44431
http://hdl.handle.net/10044/1/44431
Autor:
Rémy Denzler, Markus Stoffel
Publikováno v:
Molecular cell. 60(1)
MicroRNAs (miRNAs) are small regulatory RNAs processed from stem-loop regions of primary transcripts (pri-miRNAs), with the choice of stem-loops for initial processing largely determining what becomes a miRNA. To identify sequence and structural feat
Publikováno v:
Journal of Biological Chemistry, 290 (39)
The Journal of Biological Chemistry
The Journal of Biological Chemistry
MicroRNAs (miRNAs) are important regulators of cell-autonomous gene expression that influence many biological processes. They are also released from cells and are present in virtually all body fluids, including blood, urine, saliva, sweat, and milk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003075279d25a88301e53b5396f04dd0
https://hdl.handle.net/20.500.11850/104897
https://hdl.handle.net/20.500.11850/104897