Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rémi Rosiere"'
Publikováno v:
Expert opinion on drug delivery
Introduction: Since 1968, inhaled chemotherapy has been evaluated and has shown promising results up to phase II but has not yet reached the market. This is due to technological and clinical challenges that require to be overcome with the aim of opti
Autor:
Sophie Laurent, Pierre Gerard, Ismaël Hennia, Karim Amighi, Lionel Larbanoix, Marjorie Vermeersch, Rémi Rosiere, Nathalie Wauthoz, Selma Chraibi
Publikováno v:
European journal of pharmaceutics and biopharmaceutics, 164
Cisplatin is one of the most commonly used chemotherapy in lung cancer despite its high nephrotoxicity leading to an administration only every 3–4 weeks. This study is the first report of a preclinical investigation of therapeutic intensification c
Autor:
Ivan R. Green, Dongdong Wang, André de Villiers, Rémi Rosiere, Aude Ingels, Marco Masi, Walter Berger, Lukas Oberer, Lucia Maddau, Kirk R. Gustafson, Véronique Mathieu, Willem A. L. van Otterlo, Karim Amighi, Alexander Kornienko, Alet E. van der Westhuyzen, Antonio Evidente
Publikováno v:
Org Biomol Chem
Organic & biomolecular chemistry, 18 (40
Organic & biomolecular chemistry, 18 (40
The fungal metabolite sphaeropsidin A (SphA) has been recognised for its promising cytotoxicity, particularly towards apoptosis- and multidrug-resistant cancers. Owing to its intriguing activity, the development of SphA as a potential anticancer agen
Publikováno v:
Revue Des Maladies Respiratoires
Revue Des Maladies Respiratoires, 2018, 35 (4), pp.355-377. ⟨10.1016/j.rmr.2018.02.001⟩
Revue Des Maladies Respiratoires, 2018, 35 (4), pp.355-377. ⟨10.1016/j.rmr.2018.02.001⟩
International audience; Despite severe adverse effects, chemotherapy is still widely used in the treatment of lung tumors, including primary lung tumors and metastases. In order to reduce the risk of harm and to intensify treatment responses, several
Publikováno v:
Revue Des Maladies Respiratoires
Revue Des Maladies Respiratoires, 2018, 35 (4), pp.378-389. ⟨10.1016/j.rmr.2018.02.002⟩
Revue Des Maladies Respiratoires, 2018, 35 (4), pp.378-389. ⟨10.1016/j.rmr.2018.02.002⟩
International audience; Lung tumours have a high incidence and cause many deaths worldwide. Despite progresses in treatment with targeted therapies and immunotherapies, the global 5-year survival rate remains low. In this context, inhaled chemotherap
Autor:
Karim Amighi, E. De Prez, Rémi Rosiere, M. Remmelink, Joëlle Nortier, Nathalie Wauthoz, P Gérard, Martine Antoine, Selma Chraibi, Ingrid Langer
Publikováno v:
Biomedicine & pharmacotherapy, 139
Biomedicine & Pharmacotherapy, Vol 139, Iss, Pp 111716-(2021)
Biomedicine & Pharmacotherapy, Vol 139, Iss, Pp 111716-(2021)
Despite the advances in targeted therapies and immunotherapy for non-small cell lung cancer (NSCLC) patients, the intravenous administration of carboplatin (CARB) and paclitaxel (PTX) in well-spaced cycles is widely indicated for the treatment of NSC
Publikováno v:
International Journal of Pharmaceutics. 517:359-372
Pharmacokinetics of cisplatin administered by the pulmonary route were established in mice using dry powders inhaler (DPI) formulations showing immediate (F1) and controlled release (CR, solid lipid microparticles) in vitro, without (F2) or with PEGy
Autor:
Fahd Touzani, Rémi Rosiere, Marie-Hélène Antoine, Nathalie Wauthoz, Joëlle Nortier, Karim Amighi, Eric De Prez, Selma Chraibi
Publikováno v:
Néphrologie & Thérapeutique. 16:262-263
Introduction Malgre les progres en immunotherapie et en therapies ciblees, la chimiotherapie intraveineuse a base de cisplatine (CIS-IV) demeure le pilier central dans le traitement du cancer pulmonaire. Son administration est limitee par la nephroto
Autor:
Alejandro Nieto-Orellana, Nick Childerhouse, H. Li, Cynthia Bosquillon, Gemma Keegan, Nathalie Wauthoz, Hywel C Williams, Rémi Rosiere, Cíntia J. Monteiro, Snow Stolnik, David Coghlan, Giuseppe Mantovani
Publikováno v:
Journal of controlled release, 316
Pulmonary delivery is increasingly seen as an attractive, non-invasive route for the delivery of forthcoming protein therapeutics. In this context, here we describe protein complexes with a new ‘complexing excipient’ - vitamin B12-targeted poly(e
Publikováno v:
Cancers
Cancers, 11 (329
Cancers, Vol 11, Iss 3, p 329 (2019)
Cancers (Basel), 11 (3
Cancers, 11 (329
Cancers, Vol 11, Iss 3, p 329 (2019)
Cancers (Basel), 11 (3
Despite new treatment modalities, including targeted therapies and checkpoint inhibitors, cytotoxic chemotherapy remains central in the care of patients with lung tumors. Use of the pulmonary route to deliver chemotherapy has been proved to be feasib