A multiplex serological assay for the characterization of IgG immune response to SARS-CoV-2.

Autor: Etienne Brochot, Vianney Souplet, Pauline Follet, Pauline Ponthieu, Christophe Olivier, Gaël Even, Christophe Audebert, Rémi Malbec

Publikováno v: PLoS ONE, Vol 17, Iss 1, p e0262311 (2022)

In the fight against SARS-COV-2, the development of serological assays based on different antigenic domains represent a versatile tool to get a comprehensive picture of the immune response or differentiate infection from vaccination beyond simple dia

Externí odkaz: https://doaj.org/article/24ccb179f8954a1ab559a4364905ee0a

µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes

Autor: Rémi, Malbec, Bayan, Chami, Lorène, Aeschbach, Gustavo A, Ruiz Buendía, Marius, Socol, Pierre, Joseph, Thierry, Leïchlé, Evgeniya, Trofimenko, Aurélien, Bancaud, Vincent, Dion

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9, pp.23. ⟨10.1038/s41598-018-36632-5⟩
Scientific reports, vol. 9, no. 1, pp. 23
Scientific Reports, 2019, 9, pp.23. ⟨10.1038/s41598-018-36632-5⟩

International audience; We present µLAS, a lab-on-chip system that concentrates, separates, and detects DNA fragments in a single module. µLAS speeds up DNA size analysis in minutes using femtomolar amounts of amplified DNA. Here we tested the rele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2d1e44206b412891509602a4333bea20
http://link.springer.com/article/10.1038/s41598-018-36632-5

Microfluidics for minute DNA sample analysis: open challenges for genetic testing of cell-free circulating DNA in blood plasma

Autor: Pierre Joseph, Aurélien Bancaud, Rémi Malbec, Thierry Leichle, Jean Cacheux, Pierre Cordelier

Publikováno v: Micro and Nano Engineering
Micro and Nano Engineering, Elsevier, 2018, 1, pp.25-32. ⟨10.1016/j.mne.2018.10.003⟩
Micro and Nano Engineering, 2018, 1, pp.25-32. ⟨10.1016/j.mne.2018.10.003⟩
Micro and Nano Engineering, 2018, 1, pp.25-32. 〈10.1016/j.mne.2018.10.003〉
Micro and Nano Engineering, Vol 1, Iss, Pp 25-32 (2018)

Genetic testing based on the analysis of circulating cell-free DNA (cfDNA) in body fluids, especially blood plasma, is raising interest for the management and follow-up of many diseases, including cancer. Because the concentration of cfDNA is low and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf1294056f8396b60704ad4a2d0b01f
https://doi.org/10.1016/j.mne.2018.10.003