Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Rémi Fronzes"'
Autor:
Robin Anger, Laetitia Pieulle, Meriam Shahin, Odile Valette, Hugo Le Guenno, Artemis Kosta, Vladimir Pelicic, Rémi Fronzes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Type 4 pili (T4P) are important virulence factors, which belong to a superfamily of nanomachines ubiquitous in prokaryotes, called type 4 filaments (T4F). T4F are defined as helical polymers of type 4 pilins. Recent advances in cryo-electron
Externí odkaz:
https://doaj.org/article/d90f3c04320e420fbf14aa209a87aebe
Autor:
Solène G. Beauvois, Nicolas Flaugnatti, Marianne Ilbert, Marie Boyer, Esther Gavello-Fernandez, Rémi Fronzes, Dukas Jurėnas, Laure Journet
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Bacteria are constantly competing to colonize crowded ecological niches, such as the human gut. The type VI secretion system (T6SS) is a critical bacterial weapon in this warfare. It resembles a crossbow with a poisoned arrow allowing bacter
Externí odkaz:
https://doaj.org/article/b1c06dddf42b4d0ba43ef779c4f901f2
Autor:
Marine Blanc, Clara Lettl, Jérémy Guérin, Anaïs Vieille, Sven Furler, Sylvie Briand-Schumacher, Birgit Dreier, Célia Bergé, Andreas Plückthun, Sandrine Vadon-Le Goff, Rémi Fronzes, Patricia Rousselle, Wolfgang Fischer, Laurent Terradot
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011368 (2023)
The bacterial human pathogen Helicobacter pylori produces a type IV secretion system (cagT4SS) to inject the oncoprotein CagA into gastric cells. The cagT4SS external pilus mediates attachment of the apparatus to the target cell and the delivery of C
Externí odkaz:
https://doaj.org/article/7044c6721af0495787ccdbe2bca8e138
Autor:
Dukas Jurėnas, Leonardo Talachia Rosa, Martial Rey, Julia Chamot-Rooke, Rémi Fronzes, Eric Cascales
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Rearrangement hot spots (Rhs) proteins are bacterial polymorphic toxin systems. Here, the authors show that Rhs1 forms a complex with the Type VI secretion system (T6SS) spike protein VgrG and the EagR chaperone. They also present the cryo-EM structu
Externí odkaz:
https://doaj.org/article/3207bbe65e894dab9e6e7124d3c24849
Autor:
Matteo Tassinari, Thierry Doan, Marco Bellinzoni, Maïalene Chabalier, Mathilde Ben-Assaya, Mariano Martinez, Quentin Gaday, Pedro M. Alzari, Eric Cascales, Rémi Fronzes, Francesca Gubellini
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Type VIIb secretion systems (T7SSb) were recently proposed to mediate different aspects of Firmicutes physiology, including bacterial pathogenicity and competition. However, their architecture and mechanism of action remain largely obscure.
Externí odkaz:
https://doaj.org/article/0cfa1758735f440e96295aff9ac32bf7
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Acetaldehyde–alcohol dehydrogenase (AdhE) converts acetyl-CoA to ethanol and is a key enzyme in bacterial alcoholic fermentation. AdhE forms spirosomes and, here, the authors present the cryoEM structures of compact and extended E.coli AdhE spiroso
Externí odkaz:
https://doaj.org/article/07fa1f5397a148c884f80a53704a93fe
Autor:
Petya Violinova Krasteva, Joaquin Bernal-Bayard, Laetitia Travier, Fernando Ariel Martin, Pierre-Alexandre Kaminski, Gouzel Karimova, Rémi Fronzes, Jean-Marc Ghigo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Many Gram-negative bacteria secrete exopolysaccharides via functionally homologous synthase-dependent systems. Here the authors use electron microscopy to reveal that biofilm-promoting cellulose in E. coli is secreted by a conserved multi-component s
Externí odkaz:
https://doaj.org/article/ab686445e60b417b9ea1d321b6f21d1e
Autor:
Léa Marie, Chiara Rapisarda, Violette Morales, Mathieu Bergé, Thomas Perry, Anne-Lise Soulet, Clémence Gruget, Han Remaut, Rémi Fronzes, Patrice Polard
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helic
Externí odkaz:
https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
Autor:
Raphaël Laurenceau, Petya V Krasteva, Amy Diallo, Sahra Ouarti, Magalie Duchateau, Christian Malosse, Julia Chamot-Rooke, Rémi Fronzes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004835 (2015)
The success of S. pneumoniae as a major human pathogen is largely due to its remarkable genomic plasticity, allowing efficient escape from antimicrobials action and host immune response. Natural transformation, or the active uptake and chromosomal in
Externí odkaz:
https://doaj.org/article/1bcd4a859a984d1db0792751174fd774
Autor:
Raphaël Laurenceau, Gérard Péhau-Arnaudet, Sonia Baconnais, Joseph Gault, Christian Malosse, Annick Dujeancourt, Nathalie Campo, Julia Chamot-Rooke, Eric Le Cam, Jean-Pierre Claverys, Rémi Fronzes
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003473 (2013)
Natural genetic transformation is widely distributed in bacteria and generally occurs during a genetically programmed differentiated state called competence. This process promotes genome plasticity and adaptability in Gram-negative and Gram-positive
Externí odkaz:
https://doaj.org/article/0b3db3df9e2e462988b7f3cbc1655188