Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rémi Carpentier"'
Autor:
Maria-Victoria Hinckelmann, Frédéric Saudou, Morgane Louessard, Rémi Carpentier, Sophie Lenoir, Patricia Lino, Aurélie Genoux, Sandrine Humbert, Laura Auboyer, Anselm Perrier, Chiara Scaramuzzino, Amandine Virlogeux
Publikováno v:
I: Experimental therapeutics – preclinical.
Background Huntington Disease (HD) involves a complex cascade of pathogenic events, but central to its disruption of the cortico-striatal circuitry is impaired trafficking of Brain-Derived Neurotrophic Factor (BDNF). Aim We hypothesized that improvin
Autor:
Mariacristina Capizzi, Rémi Carpentier, Yohann Couté, Rayane Kassem, Eric Denarier, Annie Adrait, Marina Mapelli, Sandrine Humbert
Publikováno v:
Neuron
Neuron, 2022, 110 (1), pp.36-50.e5. ⟨10.1016/j.neuron.2021.10.033⟩
Neuron, 2022, 110 (1), pp.36-50.e5. ⟨10.1016/j.neuron.2021.10.033⟩
Summary Although the classic symptoms of Huntington’s disease (HD) manifest in adulthood, neural progenitor cell behavior is already abnormal by 13 weeks’ gestation. To determine how these developmental defects evolve, we turned to cell and mouse
Autor:
Rémi Carpentier, Indira Mendez-David, Fabienne Agasse, Wilhelm Christaller, Sandrine Humbert, Denis J. David, Barbara Y. Braz, Frédéric Saudou
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2020, 32, pp.107865-. ⟨10.1016/j.celrep.2020.107865⟩
Cell Reports, 2020, 32, pp.107865-. ⟨10.1016/j.celrep.2020.107865⟩
Cell Reports, Elsevier Inc, 2020, 32, pp.107865-. ⟨10.1016/j.celrep.2020.107865⟩
Cell Reports, 2020, 32, pp.107865-. ⟨10.1016/j.celrep.2020.107865⟩
Chronic exposure to stress is a major risk factor for neuropsychiatric disease, and elevated plasma corticosterone (CORT) correlates with reduced levels of both brain-derived neurotrophic factor (BDNF) and hippocampal neurogenesis. Precisely how thes