Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Rémi, Desmet"'
Autor:
Nathalie Ollivier, Magalie Sénéchal, Rémi Desmet, Benoît Snella, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Phosphorylation is a mechanism used by cells to promote proteins-biomolecules association. Here, the authors show the effect of the interactions between proteins equipped with positively charged arginines and peptides harbouring negatively charged ph
Externí odkaz:
https://doaj.org/article/35af3717c05a41b8b1e9a8f432c76bde
Publikováno v:
Organic Letters. 25:2696-2700
Autor:
Nathalie Ollivier, Thomas Toupy, Ruben C. Hartkoorn, Rémi Desmet, Jean-Christophe M. Monbaliu, Oleg Melnyk
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Flow-based peptide synthesis is a well-established method, yet difficult to combine with native chemical ligation (NCL), the go-to method for peptide cyclization. Here, the authors developed a microfluidic procedure for peptide cyclization within min
Externí odkaz:
https://doaj.org/article/b5a06ec209fc4f7f99553330779adfca
Autor:
Rémi Desmet, Céline Boidin‐Wichlacz, Reda Mhidia, Aurélie Tasiemski, Vangelis Agouridas, Oleg Melnyk
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Angewandte Chemie International Edition, 2023, ⟨10.1002/anie.202302648⟩
Autor:
Rémi Desmet, Hervé Drobecq, Oleg Melnyk, Nathalie Ollivier, Benoît Snella, Vangelis Agouridas, Jérôme Vicogne
Publikováno v:
Organic Letters
Organic Letters, 2020, 22 (21), pp.8608-8612. ⟨10.1021/acs.orglett.0c03195⟩
Organic Letters, American Chemical Society, 2020, ⟨10.1021/acs.orglett.0c03195⟩
Organic Letters, American Chemical Society, 2020, 22 (21), pp.8608-8612. ⟨10.1021/acs.orglett.0c03195⟩
Organic Letters, 2020, 22 (21), pp.8608-8612. ⟨10.1021/acs.orglett.0c03195⟩
Organic Letters, American Chemical Society, 2020, ⟨10.1021/acs.orglett.0c03195⟩
Organic Letters, American Chemical Society, 2020, 22 (21), pp.8608-8612. ⟨10.1021/acs.orglett.0c03195⟩
Hydrazone and oxime peptide ligations are catalyzed by arginine. The catalysis is assisted intramolecularly by the side-chain guanidinium group. Hydrazone ligation in the presence of arginine proceeds efficiently in phosphate buffer at neutral pH but
Autor:
Jérôme Segers, Emmanuelle Petit, Oleg Melnyk, Véronique Corbière, Sophie Lecher, Rémi Desmet, Françoise Mascart, Marc Loyens, Camille Locht
Publikováno v:
The Journal of immunology, 204 (7
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, 204 (7), pp.1715-1723. ⟨10.4049/jimmunol.1901214⟩
Journal of Immunology, 2020, 204 (7), pp.1715-1723. ⟨10.4049/jimmunol.1901214⟩
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, 204 (7), pp.1715-1723. ⟨10.4049/jimmunol.1901214⟩
Journal of Immunology, 2020, 204 (7), pp.1715-1723. ⟨10.4049/jimmunol.1901214⟩
T cell epitopes are mostly nonmodified peptides, although posttranslationally modified peptide epitopes have been described, but they originated from viral or self-proteins. In this study, we provide evidence of a bacterial methylated T cell peptide
Autor:
Oleg Melnyk, Marine Cargoët, Vangelis Agouridas, Rémi Desmet, Hervé Drobecq, Annick Blanpain, Vincent Diemer, Benoît Snella
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2018, 83 (20), pp.12584-12594. ⟨10.1021/acs.joc.8b01903⟩
Journal of Organic Chemistry, American Chemical Society, 2018, 83 (20), pp.12584-12594. ⟨10.1021/acs.joc.8b01903⟩
N-Alkyl bis(2-selanylethyl)amines catalyze the synthesis of peptide thioesters or peptide ligation from bis(2-sulfanylethyl)amido (SEA) peptides. These catalysts are generated in situ by reduction of the corresponding cyclic diselenides by tris(2-car
Autor:
Nathalie Ollivier, Jérôme Vicogne, Emmanuelle Boll, Annick Blanpain, Alexandra Mougel, Bérénice Leclercq, Hervé Drobecq, Rémi Desmet, Oleg Melnyk
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2017, 8 (8), pp.5362-5370. ⟨10.1039/c7sc01912b⟩
Chemical Science, 2017, 8 (8), pp.5362-5370. ⟨10.1039/c7sc01912b⟩
Chemical Science, The Royal Society of Chemistry, 2017, 8 (8), pp.5362-5370. ⟨10.1039/c7sc01912b⟩
Chemical Science, 2017, 8 (8), pp.5362-5370. ⟨10.1039/c7sc01912b⟩
Chemical protein synthesis gives access to well-defined native or modified proteins that are useful for studying protein structure and function. The majority of proteins synthesized up to now have been produced using native chemical ligation (NCL) in
Autor:
Jérôme Vicogne, Laurent Raibaut, Annick Blanpain, Emmanuelle Boll, Nathalie Ollivier, Hervé Drobecq, Rémi Desmet, Oleg Melnyk
Publikováno v:
Nature Protocols. 10:269-292
Small ubiquitin-like modifier (SUMO) post-translational modification (PTM) of proteins has a crucial role in the regulation of important cellular processes. This protocol describes the chemical synthesis of functional SUMO-peptide conjugates. The two
Autor:
Patricia Melnyk, Oleg Melnyk, Anthony Romieu, Hervé Drobecq, Fatima Dahmani, Rémi Desmet, Jérôme Vicogne, Véronique Fafeur, Soizic Besret
Publikováno v:
Bioconjugate Chemistry
The capacity of many proteins to interact with natural or synthetic polyanions has been exploited for modulating their biological action. However, the polydispersity of these macromolecular polyanions as well as their poor specificity is a severe lim