Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Réjean, Lapointe"'
Publikováno v:
APL Bioengineering, Vol 6, Iss 4, Pp 041502-041502-24 (2022)
Cancer immunotherapies have revolutionized the treatment of numerous cancers, with exciting results often superior to conventional treatments, such as surgery and chemotherapy. Despite this success, limitations such as limited treatment persistence a
Externí odkaz:
https://doaj.org/article/fc2e82b2dae841dca327ff4a1897bcaf
Autor:
Supriya Behl, Nancy Hamel, Manon de Ladurantaye, Stéphanie Lepage, Réjean Lapointe, Anne-Marie Mes-Masson, William D. Foulkes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Abstract Inherited germline pathogenic variants are responsible for ~5% of breast cancer globally. Through rapid expansion and isolation since immigration in the early 17th century, French Canadians are a relatively genetically homogenous founder pop
Externí odkaz:
https://doaj.org/article/b67ddaa5e9f64dcabd8141ee8ac1639b
Autor:
Typhaine Gris, Patrick Laplante, Paméla Thebault, Romain Cayrol, Ahmed Najjar, Benjamin Joannette-Pilon, Frédéric Brillant-Marquis, Elsa Magro, Shane W. English, Réjean Lapointe, Michel Bojanowski, Charles L. Francoeur, Jean-François Cailhier, on behalf of the Canadian Critical Care Translational Biology Group
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Aneurysmal subarachnoid hemorrhage (SAH) is a catastrophic disease with devastating consequences, including a high mortality rate and severe disabilities among survivors. Inflammation is induced following SAH, but the exact role a
Externí odkaz:
https://doaj.org/article/cf807618ddec4f168a80da39fe6b4434
Autor:
Khashayar Esfahani, Tho-Alfakar Al-Aubodah, Pamela Thebault, Réjean Lapointe, Marie Hudson, Nathalie A. Johnson, Dana Baran, Najwa Bhulaiga, Tomoko Takano, Jean-François Cailhier, Ciriaco A. Piccirillo, Wilson H. Miller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The use of immune checkpoint inhibitors (ICI) in cancer patients with solid organ allografts is hampered due to potential organ rejection. Here, the authors present a case report of a patient with kidney allograft and show that treatment with the mTO
Externí odkaz:
https://doaj.org/article/7b6d74e8eca445f991f3a9a988480cef
Autor:
Anne Monette, Derek Bergeron, Amira Ben Amor, Liliane Meunier, Christine Caron, Anne-Marie Mes-Masson, Nidhameddine Kchir, Kamel Hamzaoui, Igor Jurisica, Réjean Lapointe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Permanence of front-line management of lung cancer by immunotherapies requires predictive companion diagnostics identifying immune-checkpoints at baseline, challenged by the size and heterogeneity of biopsy specimens. Methods An i
Externí odkaz:
https://doaj.org/article/6eedc32598114c95ab3e4b241af8f5d0
Autor:
David Possamaï, Laïla-Aïcha Hanafi, Angélique Bellemare-Pelletier, Katia Hamelin, Paméla Thébault, Marie-Josée Hébert, Étienne Gagnon, Denis Leclerc, Réjean Lapointe
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Nanoparticles made of the coat protein of papaya mosaic virus (PapMV) and a single-strand RNA were previously shown to be an efficient antigen presentation system for the trigger of cellular immunity. Engineering of PapMV nano with a cytotoxic T lymp
Externí odkaz:
https://doaj.org/article/077699753b6e422fb8dd35551db34f88
Autor:
Nicholas Cunningham, Tommy Malaret, Paméla Thébault, Guillaume St-Jean, Feryel Azzi, Dominique Trudel, Réjean Lapointe, Sophie Lerouge
Publikováno v:
Biomaterials Science. 11:3561-3573
T cells encapsulated in an in situ gelling biodegradable hydrogel reduce tumor growth in a mouse tumor model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ccad789ec8f1b0c103fef0e2e8d090b
https://doi.org/10.1039/d2bm01795d
https://doi.org/10.1039/d2bm01795d
Autor:
Rahima Jamal, Réjean Lapointe, Eftihia Cocolakis, Paméla Thébault, Shirin Kazemi, Jennifer E. Friedmann, Jeanne Dionne, Jean-François Cailhier, Karl Bélanger, Jean-Pierre Ayoub, Huy Le, Caroline Lambert, Jida El-Hajjar, Léon C. van Kempen, Alan Spatz, Wilson H. Miller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract Background Checkpoint blockade with ipilimumab provides long-term survival to a significant proportion of patients with metastatic melanoma. New approaches to increase survival and to predict which patients will benefit from treatment are ne
Externí odkaz:
https://doaj.org/article/c038d5dcfb704f2aaa6e6160d6d158ec
Autor:
Mathieu J.F. Crupi, Douglas J. Mahoney, Rebecca C. Auer, Sarah Tucker, Adrian Pelin, D. William Cameron, Taylor R Jamieson, Ricardo Marius, John C. Bell, Réjean Lapointe, Kyle Potts, Nikolas T. Martin, Zaid Taha, Ragunath Singaravelu, Taha Azad, Jean-François Cailhier, Joanna Poutou, Bradley Austin, Jean-Simon Diallo, Emily E.F. Brown, Jack Whelan, Christiano Tanese de Souza, Sarwat T. Khan, Reza Rezaei, Julia Petryk, Carolina S. Ilkow, Stephen Boulton, Jonathan B. Angel, Jaahnavi Dave, Xiaohong He, Abera Surendran
Publikováno v:
Molecular Therapy
The coronavirus disease 2019 (COVID-19) pandemic requires the continued development of safe, long-lasting, and efficacious vaccines for preventive responses to major outbreaks around the world, and especially in isolated and developing countries. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced3ac178fb2f00d670fc6f132c57efc
https://doi.org/10.1016/j.ymthe.2021.10.008
https://doi.org/10.1016/j.ymthe.2021.10.008
Autor:
Mayra S. Carneiro, Yacine Bareche, Cheng Zhao, Pamela Thébault, Kurosh Rahimi, Diane Provencher, Vanessa Samouélian, Béatrice Cormier, Jean-François Cailhier, Anne-Marie Mes-Masson, Sophie Petropoulos, John Stagg, Réjean Lapointe
Characterizing T cell populations and understanding their developmental relationships may help design more effective cancer immunotherapies. We coupled single-cell transcriptomics and T cell receptor (TCR) αβ profiling of intratumoral and periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbaa2f565d3879c2b0a0f9cc1f01bcb3
https://doi.org/10.1101/2023.02.28.530488
https://doi.org/10.1101/2023.02.28.530488
