Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Réjean, Couture"'
Autor:
Vincent Minville, Lionel Mouledous, Acil Jaafar, Réjean Couture, Anne Brouchet, Bernard Frances, Ivan Tack, Jean-Pierre Girolami
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Tibial fracture is associated with inflammatory reaction leading to severe pain syndrome. Bradykinin receptor activation is involved in inflammatory reactions, but has never been investigated in fracture pain. Methods This study a
Externí odkaz:
https://doaj.org/article/79539ea68a334e4e9b5ca38d06b1bdb9
Publikováno v:
Cells, Vol 10, Iss 8, p 1913 (2021)
The kallikrein-kinin system (KKS) contributes to retinal inflammation and neovascularization, notably in diabetic retinopathy (DR) and neovascular age-related macular degeneration (AMD). Bradykinin type 1 (B1R) and type 2 (B2R) receptors are G-protei
Externí odkaz:
https://doaj.org/article/7ae6c12b2be54916b825ed1b894cc02e
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Compelling evidence suggests a role for the inducible nitric oxide synthase, iNOS, and the bradykinin type 1 receptor (B1R) in diabetic retinopathy, including a possible control of the expression and activity of iNOS by B1R. In diabetic retina, both
Externí odkaz:
https://doaj.org/article/773e1c7cc24d4d5c996103b68cde6ff7
Autor:
Trevor Rajchgot, Sini Christine Thomas, Jo-Chiao Wang, Maryam Ahmadi, Mohammad Balood, Théo Crosson, Jenny Pena Dias, Réjean Couture, Audrey Claing, Sébastien Talbot
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Diabetes is a common condition characterized by persistent hyperglycemia. High blood sugar primarily affects cells that have a limited capacity to regulate their glucose intake. These cells include capillary endothelial cells in the retina, mesangial
Externí odkaz:
https://doaj.org/article/9e4c90477b1a41c782b24953395da944
Autor:
Bruce Zuraw, Doug Pettibone, Werner Muller-Esterl, Francois Marceau, Fredrik Leeb-Lundberg, Fernand Gobeil Jr, Alexander Faussner, Réjean Couture, Joseph Coulson
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Bradykinin (or kinin) receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Bradykinin (kinin) Receptors [92]) are activated by the endogenous peptides bradykinin (BK), [des-Arg9]bradykinin, Lys-BK (kallidin), [des-Arg10]kallidin, [Phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61593655d43f07d86f23ceb353e60c98
https://doi.org/10.2218/gtopdb/f10/2023.1
https://doi.org/10.2218/gtopdb/f10/2023.1
Publikováno v:
Pharmaceuticals, Vol 13, Iss 6, p 130 (2020)
Kinins are vasoactive peptides and mediators of inflammation, which signal through two G protein-coupled receptors, B1 and B2 receptors (B1R, B2R). Recent pre-clinical findings suggest a primary role for B1R in a rat model of wet age-related macular
Externí odkaz:
https://doaj.org/article/e7e5fd819c7345b0b0e1827aa75cf7b3
Autor:
Youssef Haddad, Réjean Couture
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Kinin B1 receptor (B1R) enhanced superoxide anion (O2•-) production in the vasculature of diabetic rats. This study investigates the induction and distribution of B1R in diabetic blood vessels and addresses the hypothesis that B1R is co-localized w
Externí odkaz:
https://doaj.org/article/60e4c0d16bd44332805bcb91b4088f46
Autor:
Youssef Haddad, Réjean Couture
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Kinin B1 receptor (B1R) contributes to insulin resistance, an early event in type 2 diabetes, through the upregulation and activation of the inducible form of nitric oxide synthase (iNOS), pro-inflammatory cytokines and the oxidative stress. This stu
Externí odkaz:
https://doaj.org/article/a9b784ebe0a54ccc906082a3c763f4b3
Autor:
Karine Bibeau, Benoit Sicotte, Mélanie Béland, Menakshi Bhat, Louis Gaboury, Réjean Couture, Jean St-Louis, Michèle Brochu
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145982 (2016)
Lower maternal plasma volume expansion was found in idiopathic intrauterine growth restriction (IUGR) but the link remains to be elucidated. An animal model of IUGR was developed by giving a low-sodium diet to rats over the last week of gestation. Th
Externí odkaz:
https://doaj.org/article/af19a4dd409f469fbc51f76d69b69a75
Publikováno v:
Journal of Cellular and Molecular Medicine
δ‐opioid receptor (DOPr) agonists have analgesic efficacy in chronic pain models but development of tolerance limits their use for long‐term pain management. Although agonist potential for inducing acute analgesic tolerance has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ff506e7002bccca9fbf8319b143005
http://europepmc.org/articles/PMC7214178
http://europepmc.org/articles/PMC7214178