Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Régis E. Meyer"'
Autor:
Régis E Meyer, Ashlea Sartin, Madeline Gish, Jillian Harsha, Emily Wilkie, Dawson Haworth, Rebecca LaVictoire, Isabel Alberola, Hoa H Chuong, Gary J Gorbsky, Dean S Dawson
Publikováno v:
bioRxiv
Tumor cell lines with elevated chromosome numbers frequently have correlated elevations of Mps1 expression and these tumors are more dependent on Mps1 activity for their survival than control cell lines. Mps1 is a conserved kinase involved in control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5566054b2ecec9c2132f77b7952ff4b
https://doi.org/10.1101/2023.01.09.523325
https://doi.org/10.1101/2023.01.09.523325
Proper chromosome segregation in meiosis I relies on the formation of connections between homologous chromosomes. Crossovers between homologs provide a connection that allows them to attach correctly to the meiosis I spindle. Tension is transmitted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b1637c347ee78a960d7e7678921fad
https://doi.org/10.1101/2022.12.19.520819
https://doi.org/10.1101/2022.12.19.520819
Publikováno v:
Molecular Biology of the Cell
In prophase of meiosis I, homologous chromosomes pair and become connected by cross-overs. Chiasmata, the connections formed by cross-overs, enable the chromosome pair, called a bivalent, to attach as a single unit to the spindle. When the meiotic sp
Autor:
Guillermo A Orsi, Ahmed Algazeery, Régis E Meyer, Michèle Capri, Laure M Sapey-Triomphe, Béatrice Horard, Henri Gruffat, Pierre Couble, Ounissa Aït-Ahmed, Benjamin Loppin
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003285 (2013)
The differentiation of post-meiotic spermatids in animals is characterized by a unique reorganization of their nuclear architecture and chromatin composition. In many species, the formation of sperm nuclei involves the massive replacement of nucleoso
Externí odkaz:
https://doaj.org/article/2dfdc87fbaa04cc88a0133f988abb022
In prophase of meiosis I, homologous partner chromosomes pair and become connected by crossovers. Chiasmata, the connections formed between the partners enable the chromosome pair, called a bivalent, to attach as a single unit to the spindle. When th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b044456d1421f7d5b8b758af50332b
https://doi.org/10.1101/2020.06.28.176370
https://doi.org/10.1101/2020.06.28.176370
In aneuploid cancer cells, the chromosome segregation apparatus is sensitive to increased chromosome number. The conserved protein kinase, Mps1, is a critical actor of this machinery, orienting the chromosomes properly on the spindle. Abnormally high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762fa03dc55b38d188d80b26ac1ff535
https://doi.org/10.1101/2020.03.26.006387
https://doi.org/10.1101/2020.03.26.006387
Publikováno v:
Molecular Biology of the Cell. 29:479-489
In budding yeast meiosis, homologous chromosomes become linked by chiasmata and then move back and forth on the spindle until they are bioriented, with the kinetochores of the partners attached to microtubules from opposite spindle poles. Certain mut
Autor:
Dean S. Dawson, Régis E. Meyer
Publikováno v:
Genes & Development. 34:147-148
The distinctive segregation patterns of chromosomes in mitosis and meiosis are dictated in part by the kinetochores, the structures on chromosomes that attach them to the microtubules of the spindle. Inappropriate mitosis-like chromosome segregation
Autor:
Roberto J. Pezza, Alberto M. Pendás, Emily L Kurdzo, Régis E. Meyer, Dean S. Dawson, Laura Gómez-H, Mara N Gladstone, Luciana Previato de Almeida, Hoa H. Chuong, Craig Eyster, Jared M. Evatt, Elena Llano
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Proceedings of the National Academy of Sciences of the United States of America
instname
Proceedings of the National Academy of Sciences of the United States of America
© 2019 the Author(s).
Faithful chromosome segregation during meiosis I depends upon the formation of connections between homologous chromosomes. Crossovers between homologs connect the partners, allowing them to attach to the meiotic spindle as
Faithful chromosome segregation during meiosis I depends upon the formation of connections between homologous chromosomes. Crossovers between homologs connect the partners, allowing them to attach to the meiotic spindle as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f248c7f5713162f58e7d39aae31ba85
http://hdl.handle.net/10261/203861
http://hdl.handle.net/10261/203861
Autor:
Christina L Hansen, Marrett Hild, Régis E. Meyer, Dean S. Dawson, Hoa H. Chuong, Michael Kinter
Publikováno v:
Molecular Biology of the Cell
In meiosis I, the centromeres of sister chromatids are pulled, together, toward the same pole of the spindle. In mitotis, the opposite is true—sister centromeres are pulled apart. This study explores the manner in which mitotic outer kinetochores a