Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Régen Drouin"'
Autor:
Shuaa Basalom, Mélissa Fiscaletti, Valancy Miranda, Céline Huber, Guillaume Couture, Régen Drouin, Élise Monceau, Sandrine Wavrant, Johanne Dubé, Outi Mäkitie, Valérie Cormier-Daire, Philippe M. Campeau
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101121- (2021)
Calvarial Doughnut Lesions with Bone Fragility (CDL) is an autosomal dominant genetic disease, characterized by low bone mineral density, multiple fractures starting in childhood, and sclerotic doughnut-shaped lesions in the cranial bones. Aubé and
Externí odkaz:
https://doaj.org/article/6c4338674a744c41909ce3f1c0910c71
Autor:
Macoura Gadji, Shubha Mathur, Brigitte Bélanger, Jaganmohan Reddy Jangamreddy, Josée Lamoureux, Ana Maria Crous Tsanaclis, David Fortin, Régen Drouin, Sabine Mai
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8539 (2020)
Mechanisms of recurrence in oligodendrogliomas are poorly understood. Recurrence might be driven by telomere dysfunction-mediated genomic instability. In a pilot study, we investigated ten patients with oligodendrogliomas at the time of diagnosis (fi
Externí odkaz:
https://doaj.org/article/83a225bf50564009a2f3d84942f88df1
Autor:
Macoura Gadji, David Fortin, Ana-Maria Tsanaclis, Yuval Garini, Nir Katzir, Yifat Wienburg, Ju Yan, Ludger Klewes, Thomas Klonisch, Régen Drouin, Sabine Mai
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 2, Pp 183-191 (2010)
The absence of biological markers allowing for the assessment of the evolution and prognosis of glioblastoma (GBM) is a major impediment to the clinical management of GBM patients. The observed variability in patients' treatment responses and in outc
Externí odkaz:
https://doaj.org/article/bf53f3278a5f4c44a179ff57ffbde031
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16409 (2011)
BackgroundIn 1986, two Canadian geneticists had demonstrated that Joseph Merrick, better known as the Elephant Man, suffered from the Proteus syndrome and not from neurofibromatosis type 1 (NF1), as was alleged by dermatologist Parkes in 1909. Despit
Externí odkaz:
https://doaj.org/article/8433a993374a4780a1699e839788f21c
Publikováno v:
PLoS ONE, Vol 6, Iss 4 (2011)
Externí odkaz:
https://doaj.org/article/e2bde1e083c14b57a5b6f8671b4fbc3f
Autor:
Alexandre Montpetit, Stéphanie Côté, Edna Brustein, Christian A Drouin, Line Lapointe, Michèle Boudreau, Caroline Meloche, Régen Drouin, Thomas J Hudson, Pierre Drapeau, Patrick Cossette
Publikováno v:
PLoS Genetics, Vol 4, Iss 12, p e1000296 (2008)
Adaptor protein (AP) complexes regulate clathrin-coated vesicle assembly, protein cargo sorting, and vesicular trafficking between organelles in eukaryotic cells. Because disruption of the various subunits of the AP complexes is embryonic lethal in t
Externí odkaz:
https://doaj.org/article/bae3582b1117499da4a82e3d2a4f1dc3
p53 is a master transcription factor that prevents neoplasia and genomic instability. It is an important target for anticancer drug design. Understanding the molecular mechanisms behind its transcriptional activities in normal cells is a prerequisite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b339675d7524c212145882e26f68ca6
https://doi.org/10.1158/0008-5472.c.6500258
https://doi.org/10.1158/0008-5472.c.6500258
Supplementary Figures 1-3, Table 1 from p53 Pre- and Post-Binding Event Theories Revisited: Stresses Reveal Specific and Dynamic p53-Binding Patterns on the p21 Gene Promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfa5202fba604ba0b7a2a3dcb77393d
https://doi.org/10.1158/0008-5472.22382594.v1
https://doi.org/10.1158/0008-5472.22382594.v1
Autor:
Antoine Cossette, Julie Castilloux, Chantal Bouffard, Julie Laflamme, Christophe Faure, Sami Benlamlih, Florian Abel, Michael Beecroft, Mira Francis, Régen Drouin
Publikováno v:
Can Liver J
BACKGROUND: This report describes a unique case of long-term survival of a young girl who was diagnosed with severe, rapidly progressive lysosomal acid lipase deficiency (LAL-D; historically “Wolman disease”) at three months of age and began rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a260f5ef4ef7c5c775f5b698392d6a88
https://europepmc.org/articles/PMC9473556/
https://europepmc.org/articles/PMC9473556/
Autor:
Valancy Miranda, Melissa Fiscaletti, Philippe M. Campeau, Johanne Dubé, Shuaa Basalom, Elise Monceau, Céline Huber, Régen Drouin, Outi Mäkitie, Guillaume Couture, Valérie Cormier-Daire, Sandrine Wavrant
Publikováno v:
Bone Reports
Bone Reports, Vol 15, Iss, Pp 101121-(2021)
Bone Reports, Vol 15, Iss, Pp 101121-(2021)
Calvarial Doughnut Lesions with Bone Fragility (CDL) is an autosomal dominant genetic disease, characterized by low bone mineral density, multiple fractures starting in childhood, and sclerotic doughnut-shaped lesions in the cranial bones. Aubé and