Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rébécca Phaëton"'
Autor:
Alex S. Choi, Laura M. Jenkins-Lane, Wade Barton, Asha Kumari, Carly Lancaster, Calen Raulerson, Hao Ji, Diego Altomare, Mark D. Starr, Regina Whitaker, Rebecca Phaeton, Rebecca Arend, Michael Shtutman, Andrew B. Nixon, Nadine Hempel, Nam Y. Lee, Karthikeyan Mythreye
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pathway. Central to the success of
Externí odkaz:
https://doaj.org/article/ed54a9e793e64950bc11bf6731d8ff90
Autor:
Zainab Shonibare, Mehri Monavarian, Kathleen O’Connell, Diego Altomare, Abigail Shelton, Shubham Mehta, Renata Jaskula-Sztul, Rebecca Phaeton, Mark D. Starr, Regina Whitaker, Andrew Berchuck, Andrew B. Nixon, Rebecca C. Arend, Nam Y. Lee, C. Ryan Miller, Nadine Hempel, Karthikeyan Mythreye
Publikováno v:
Cell Reports, Vol 40, Iss 4, Pp 111066- (2022)
Summary: Growth factors in tumor environments are regulators of cell survival and metastasis. Here, we reveal the dichotomy between TGF-β superfamily growth factors BMP and TGF-β/activin and their downstream SMAD effectors. Gene expression profilin
Externí odkaz:
https://doaj.org/article/20e1a0843b1f45028091a733956f68ac
Publikováno v:
Oncology Reviews, Vol 12, Iss 1 (2018)
Ovarian cancer is the leading cause of mortality among gynecologic malignancies, with most cases diagnosed at an advanced stage. Despite an initial response, most develop a recurrence and subsequent resistance to standard therapies. Pemetrexed (Alimt
Externí odkaz:
https://doaj.org/article/3cde1e31c7f74f78a6b3720fd0666744
Autor:
Zewei Jiang, Joseph Albanese, Joshua Kesterson, Joshua Warrick, Rouzan Karabakhtsian, Ekaterina Dadachova, Rébécca Phaëton
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1289-1295 (2019)
Nearly all cases of cervical cancer are initiated by persistent infection with high-risk strains of human papillomavirus (hr-HPV). When hr-HPV integrates into the host genome, the constitutive expression of oncogenic HPV proteins E6 and E7 function t
Externí odkaz:
https://doaj.org/article/7a79adf7076c4f8caf013fd250ed9164
Autor:
Beth L. Worley, Yeon Soo Kim, Jennifer Mardini, Rameez Zaman, Kelly E. Leon, Piyushi Gupta Vallur, Asvelt Nduwumwami, Joshua I. Warrick, Patrick F. Timmins, Joshua P. Kesterson, Rébécca Phaëton, Nam Y. Lee, Vonn Walter, Lauren Endres, Karthikeyan Mythreye, Katherine M. Aird, Nadine Hempel
Publikováno v:
Redox Biology, Vol 25, Iss , Pp - (2019)
Ovarian cancer remains the most lethal gynecologic malignancy, and is primarily diagnosed at late stage when considerable metastasis has occurred in the peritoneal cavity. At late stage abdominal cavity ascites accumulation provides a tumor-supportin
Externí odkaz:
https://doaj.org/article/0ee39ed6b42940489efa251bb7ae9eb6
Publikováno v:
Antioxidants, Vol 6, Iss 4, p 86 (2017)
While loss of antioxidant expression and the resultant oxidant-dependent damage to cellular macromolecules is key to tumorigenesis, it has become evident that effective oxidant scavenging is conversely necessary for successful metastatic spread. This
Externí odkaz:
https://doaj.org/article/e5851537953b44cdb5d8b86bc97a8060