Zobrazeno 1 - 10
of 220
pro vyhledávání: '"RÍOS, SEBASTIÁN"'
Autor:
Espinel-Ríos, Sebastián, Mo, Joyce Qiaoxi, Zhang, Dongda, del Rio-Chanona, Ehecatl Antonio, Avalos, José L.
Efficient multiple setpoint tracking can enable advanced biotechnological applications, such as maintaining desired population levels in co-cultures for optimal metabolic division of labor. In this study, we employ reinforcement learning as a control
Externí odkaz:
http://arxiv.org/abs/2411.09177
This work presents an omics-driven modeling pipeline that integrates machine-learning tools to facilitate the dynamic modeling of multiscale biological systems. Random forests and permutation feature importance are proposed to mine omics datasets, gu
Externí odkaz:
http://arxiv.org/abs/2410.18864
Autor:
Espinel-Ríos, Sebastián, Behrendt, Gerrich, Bauer, Jasmin, Morabito, Bruno, Pohlodek, Johannes, Schütze, Andrea, Findeisen, Rolf, Bettenbrock, Katja, Klamt, Steffen
Optogenetic modulation of adenosine triphosphatase (ATPase) expression represents a novel approach to maximize bioprocess efficiency by leveraging enforced adenosine triphosphate (ATP) turnover. In this study, we experimentally implement a model-base
Externí odkaz:
http://arxiv.org/abs/2401.08556
Metabolic cybergenetics is a promising concept that interfaces gene expression and cellular metabolism with computers for real-time dynamic metabolic control. The focus is on control at the transcriptional level, serving as a means to modulate intrac
Externí odkaz:
http://arxiv.org/abs/2401.00670
We outline a modeling and optimization strategy for investigating dynamic metabolic engineering interventions. Our framework is particularly useful at the early stages of research and development, often constrained by limited knowledge and experiment
Externí odkaz:
http://arxiv.org/abs/2310.17179
Autor:
Espinel-Ríos, Sebastián, Morabito, Bruno, Pohlodek, Johannes, Bettenbrock, Katja, Klamt, Steffen, Findeisen, Rolf
Biotechnology offers many opportunities for the sustainable manufacturing of valuable products. The toolbox to optimize bioprocesses includes \textit{extracellular} process elements such as the bioreactor design and mode of operation, medium formulat
Externí odkaz:
http://arxiv.org/abs/2302.02177
Publikováno v:
Hybrid Artificial Intelligent Systems. HAIS 2022. Lecture Notes in Computer Science(), vol 13469
Credit scoring models are the primary instrument used by financial institutions to manage credit risk. The scarcity of research on behavioral scoring is due to the difficult data access. Financial institutions have to maintain the privacy and securit
Externí odkaz:
http://arxiv.org/abs/2301.01212
For more than a half-century, credit risk management has used credit scoring models in each of its well-defined stages to manage credit risk. Application scoring is used to decide whether to grant a credit or not, while behavioral scoring is used mai
Externí odkaz:
http://arxiv.org/abs/2204.06122
Autor:
Pennington, Oliver, Espinel Ríos, Sebastián, Sebastian, Mauro Torres, Dickson, Alan, Zhang, Dongda
Publikováno v:
In Metabolic Engineering November 2024 86:274-287
Publikováno v:
Expert Systems with Applications, 2022, 118809
The thin-file borrowers are customers for whom a creditworthiness assessment is uncertain due to their lack of credit history; many researchers have used borrowers' relationships and interactions networks in the form of graphs as an alternative data
Externí odkaz:
http://arxiv.org/abs/2111.13666