Zobrazeno 1 - 10
of 303
pro vyhledávání: '"R, Zollinger"'
Autor:
Daniel R Zollinger, Elizabeth Rivers, Alexander Fine, Yanmei Huang, Joseph Son, Akshita Kalyan, Wren Gray, Golshid Baharian, Carly Hammond, Rosalyn Ram, Lindsay Ringman, Dina Hafez, Daniel Savel, Vipul Patel, Marc Dantone, Cui Guo, Merrida Childress, Chang Xu, Dorhyun Johng, Brett Wallden, Prapti Pokharel, William Camara, Priti S Hegde, Jason Hughes, Corey Carter, Nicole Davarpanah, Viraj Degaonkar, Pratyush Gupta, Sanjeev Mariathasan, Thomas Powles, Sean Ferree, Lucas Dennis, Amanda Young
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302129 (2024)
Emerging technologies focused on the detection and quantification of circulating tumor DNA (ctDNA) in blood show extensive potential for managing patient treatment decisions, informing risk of recurrence, and predicting response to therapy. Currently
Externí odkaz:
https://doaj.org/article/3fc28d0921b64f258d166f8cdf7339fa
Autor:
Thomas Powles, Amanda Young, Halla Nimeiri, Russell W. Madison, Alexander Fine, Daniel R. Zollinger, Yanmei Huang, Chang Xu, Ole V. Gjoerup, Vasily N. Aushev, Hsin-Ta Wu, Alexey Aleshin, Corey Carter, Nicole Davarpanah, Viraj Degaonkar, Pratyush Gupta, Sanjeev Mariathasan, Erica Schleifman, Zoe June Assaf, Geoffrey Oxnard, Priti S. Hegde
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCirculating tumor DNA (ctDNA) detection postoperatively may identify patients with urothelial cancer at a high risk of relapse. Pragmatic tools building off clinical tumor next-generation sequencing (NGS) platforms could have the potentia
Externí odkaz:
https://doaj.org/article/b572edde61804227913dfd5bf63af668
Autor:
Sara Lonardi, Halla Nimeiri, Chang Xu, Daniel R. Zollinger, Russell W. Madison, Alexander D. Fine, Ole Gjoerup, Cosimo Rasola, Valentina Angerilli, Shruti Sharma, Hsin-Ta Wu, Charuta C. Palsuledesai, Meenakshi Malhotra, Alexey Aleshin, Fotios Loupakis, Elise Renkonen, Priti Hegde, Matteo Fassan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11529 (2022)
A majority of patients with metastatic colorectal cancer (mCRC) experience recurrence post curative-intent surgery. The addition of adjuvant chemotherapy has shown to provide limited survival benefits when applied to all patients. Therefore, a biomar
Externí odkaz:
https://doaj.org/article/2b29f6cadbc445f9896224eac9cb48ac
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Carina Shiau, Jennifer Su, Payman Yadollahpour, Jason W. Reeves, Youngmi Kim, Sean Kim, Mark Gregory, Prajan Divakar, Eric Miller, Michael Rhodes, Sarah Warren, Erroll Rueckert, Kit Fuhrman, Daniel R. Zollinger, Robin Fropf, Joseph M. Beechem, Arnav Mehta, Toni Delorey, Cristin McCabe, Jaimie L. Barth, Piotr Zelga, Cristina R. Ferrone, Motaz Qadan, Keith D. Lillemoe, Rakesh K. Jain, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Orit Rozenblatt-Rosen, Andrew J. Aguirre, Carlos Fernandez-Del Castillo, Andrew S. Liss, Mari Mino-Kenudson, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Cancer Research. 82:SY12-04
Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer mortality in the United States by 2030. Given that resistance to cytotoxic therapy is pervasive, there is a critical need to elucidate salient gene expressi
Autor:
Zhuohe Liu, Xiaoyu Lu, Vincent Villette, Yueyang Gou, Kevin L. Colbert, Shujuan Lai, Sihui Guan, Michelle A. Land, Jihwan Lee, Tensae Assefa, Daniel R. Zollinger, Maria M. Korympidou, Anna L. Vlasits, Michelle M. Pang, Sharon Su, Changjia Cai, Emmanouil Froudarakis, Na Zhou, Saumil S. Patel, Cameron L. Smith, Annick Ayon, Pierre Bizouard, Jonathan Bradley, Katrin Franke, Thomas R. Clandinin, Andrea Giovannucci, Andreas S. Tolias, Jacob Reimer, Stéphane Dieudonné, François St-Pierre
Publikováno v:
Cell
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
Cell, 2022, 185 (18), pp.3408-3425.e29. ⟨10.1016/j.cell.2022.07.013⟩
International audience; Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics with cell-type specificity. However, current indicators enable a narrow range of applications due to poor performance under two-photon m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628e7939a22097f1a78b007bb0e76580
https://hal.science/hal-03795400/document
https://hal.science/hal-03795400/document
Autor:
Veronique Amor, Chuansheng Zhang, Anna Vainshtein, Ao Zhang, Daniel R Zollinger, Yael Eshed-Eisenbach, Peter J Brophy, Matthew N Rasband, Elior Peles
Publikováno v:
eLife, Vol 6 (2017)
A high density of Na+ channels at nodes of Ranvier is necessary for rapid and efficient action potential propagation in myelinated axons. Na+ channel clustering is thought to depend on two axonal cell adhesion molecules that mediate interactions betw
Externí odkaz:
https://doaj.org/article/d413c2b8c31449edb49d2a41b7f1a9d2
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Payman Yadollahpour, Jason W. Reeves, Rahul Mohan, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Orr Ashenberg, Samouil L. Farhi, Denis Schapiro, Prajan Divakar, Eric Miller, Daniel R. Zollinger, George Eng, Jason M. Schenkel, Jennifer Su, Carina Shiau, Patrick Yu, William A. Freed-Pastor, Domenic Abbondanza, Arnav Mehta, Joshua Gould, Conner Lambden, Caroline B. M. Porter, Alexander Tsankov, Danielle Dionne, Julia Waldman, Michael S. Cuoco, Lan Nguyen, Toni Delorey, Devan Phillips, Jaimie L. Barth, Marina Kem, Clifton Rodrigues, Debora Ciprani, Jorge Roldan, Piotr Zelga, Vjola Jorgji, Jonathan H. Chen, Zackery Ely, Daniel Zhao, Kit Fuhrman, Robin Fropf, Joseph M. Beechem, Jay S. Loeffler, David P. Ryan, Colin D. Weekes, Cristina R. Ferrone, Motaz Qadan, Martin J. Aryee, Rakesh K. Jain, Donna S. Neuberg, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Andrew J. Aguirre, Orit Rozenblatt-Rosen, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, Andrew S. Liss, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Nat Genet
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we construct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52fea7e3e72f452826d1f68df747811
https://europepmc.org/articles/PMC10290535/
https://europepmc.org/articles/PMC10290535/
Autor:
Erin Piazza, Isgur L, Lasley Ae, Nelson Js, Appelbe O, Joseph M. Beechem, Yan Liang, Maddy Griswold, Klock A, Kulasekara Br, Margaret L. Hoang, Buhr Dl, Huynh Q, Daniel R. Zollinger, Karen Nguyen, Kutchma A, Zimmerman Sm, Arya Bahrami, Kit Fuhrman, Rininger A, Robin Fropf, Rich Boykin, Jill McKay-Fleisch, Michael Rhodes
Publikováno v:
Genome research. 32(10)
Emerging spatial profiling technology has enabled high-plex molecular profiling in biological tissues, preserving the spatial and morphological context of gene expression. Here we describe expanding the chemistry for the Digital Spatial Profiling pla
Autor:
Cristina R. Ferrone, Eugene Drokhlyansky, Arnav Mehta, Conner Lambden, Alexander M. Tsankov, Joseph M. Beechem, Devan Phillips, Joshua Gould, David T. Ting, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, David P. Ryan, Orr Ashenberg, Nicholas Van Wittenberghe, Caroline B. M. Porter, Lan Nguyen, Jason M. Schenkel, Hannah I. Hoffman, Robin Fropf, Domenic Abbondanza, Jay S. Loeffler, Julia Waldman, Theodore S. Hong, Karthik A. Jagadeesh, William A. Freed-Pastor, Payman Yadollahpour, Kit Fuhrman, Rahul Mohan, Denis Schapiro, Jimmy A. Guo, Toni Delorey, Tyler Jacks, George Eng, Aviv Regev, Daniel R. Zollinger, Andrew J. Aguirre, Marina Kern, Jennifer Y. Wo, William L. Hwang, Colin D. Weekes, Jason Reeves, Michael S. Cuoco, Samouil L. Farhi, Danielle Dionne, Andrew S. Liss, Clifton Rodrigues, Orit Rozenblatt-Rosen, Debora Ciprani
Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease. Characterizing PDAC by mRNA profiling remains particularly challenging. Previously identified bulk expression subtypes were influenced by contaminating stroma and have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b837cebbfc344411d0b7ea0eac981318
https://doi.org/10.1101/2020.08.25.267336
https://doi.org/10.1101/2020.08.25.267336
Autor:
Daniel R, Zollinger, Stan E, Lingle, Kristina, Sorg, Joseph M, Beechem, Christopher R, Merritt
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2148
RNA in situ hybridization (ISH) is a widely used technique for the localization of mRNA in tissues. Limitations to traditional ISH include the number of targets that can be analyzed concurrently and the ability for many of these assays to be used in