Zobrazeno 1 - 10
of 205
pro vyhledávání: '"R, Woollard"'
Autor:
Sonja Suvakov, Hajrunisa Cubro, Wendy M. White, Yvonne S. Butler Tobah, Tracey L. Weissgerber, Kyra L. Jordan, Xiang Y. Zhu, John R. Woollard, Fouad T. Chebib, Natasa M. Milic, Joseph P. Grande, Ming Xu, Tamara Tchkonia, James L. Kirkland, Lilach O. Lerman, Vesna D. Garovic
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Background Preeclampsia is a pregnancy-specific hypertensive disorder characterized by impaired angiogenesis. We postulate that senescence of mesenchymal stem cells (MSC), multipotent cells with pro-angiogenic activities, is one of the mecha
Externí odkaz:
https://doaj.org/article/130b90b7b9b840e48df08fc38360e418
Autor:
Yu Zhao, Adrian Santelli, Xiang-Yang Zhu, Xin Zhang, John R. Woollard, Xiao-Jun Chen, Kyra L. Jordan, James Krier, Hui Tang, Ishran Saadiq, Amir Lerman, Lilach O. Lerman
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Endothelial progenitor cells (EPCs) patrols the circulation and contributes to endothelial cell regeneration. Atherosclerotic renal artery stenosis (ARAS) induces microvascular loss in the stenotic kidney (STK). Low-energy shockwave therapy (SW) can
Externí odkaz:
https://doaj.org/article/e4d8adde53204013b5eed240d29faa6b
Autor:
Sabena M. Conley, LaTonya J. Hickson, Todd A. Kellogg, Travis McKenzie, Julie K. Heimbach, Timucin Taner, Hui Tang, Kyra L. Jordan, Ishran M. Saadiq, John R. Woollard, Busra Isik, Mohsen Afarideh, Tamar Tchkonia, James L. Kirkland, Lilach O. Lerman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundChronic inflammatory conditions like obesity may adversely impact the biological functions underlying the regenerative potential of mesenchymal stromal/stem cells (MSC). Obesity can impair MSC function by inducing cellular senescence, a gro
Externí odkaz:
https://doaj.org/article/8ae03efeb23946dc90e24f4a0ac798dd
Autor:
Sabena M. Conley, John E. Shook, Xiang-Yang Zhu, Alfonso Eirin, Kyra L. Jordan, John R. Woollard, Busra Isik, LaTonya J. Hickson, Amrutesh S. Puranik, Lilach O. Lerman
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Mesenchymal stromal/stem cells (MSCs) belong to the endogenous cellular reparative system, and can be used exogenously in cell-based therapy. MSCs release extracellular vesicles (EVs), including exosomes and microvesicles, which mediate some of their
Externí odkaz:
https://doaj.org/article/6038912ef95847c8ac2184f666003f2c
Autor:
Adrian Santelli, In O. Sun, Alfonso Eirin, Abdelrhman M. Abumoawad, John R. Woollard, Amir Lerman, Stephen C. Textor, Amrutesh S. Puranik, Lilach O. Lerman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)
Background Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a nox
Externí odkaz:
https://doaj.org/article/b74fa03596b2481db9849560d6985c61
Autor:
Aditya S. Pawar, Alfonso Eirin, James D. Krier, John R. Woollard, Xiang-Yang Zhu, Amir Lerman, Andre J. van Wijnen, Lilach O. Lerman
Publikováno v:
Stem Cell Research, Vol 37, Iss , Pp - (2019)
Introduction: Mesenchymal stem cells (MSCs) possess endogenous reparative properties and may serve as an exogenous therapeutic intervention in patients with chronic kidney disease. Cardiovascular risk factors clustering in the metabolic syndrome (Met
Externí odkaz:
https://doaj.org/article/98a7ee7f6f5a4a11bd92d4cb8d35cebd
Autor:
Fang Yuan, Liang Guo, Kyoung‐Ha Park, John R. Woollard, Kwon Taek‐Geun, Kai Jiang, Tamene Melkamu, Bin Zang, Samantha L. Smith, Scott C. Fahrenkrug, Frank D. Kolodgie, Amir Lerman, Renu Virmani, Lilach O. Lerman, Daniel F. Carlson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 6 (2018)
BackgroundOssabaw pigs are unique miniature swine with genetic predisposition to develop metabolic syndrome and coronary atherosclerosis after extended periods receiving atherogenic diets. We have hypothesized that transgenic Ossabaw swine expressing
Externí odkaz:
https://doaj.org/article/abb49c944b7f46ea895f180b9f9ca8f7
Autor:
Alfonso Eirin, Xiang-Yang Zhu, Amrutesh S Puranik, John R Woollard, Hui Tang, Surendra Dasari, Amir Lerman, Andre J van Wijnen, Lilach O Lerman
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174303 (2017)
BACKGROUND:Mesenchymal stromal/stem cell (MSC) transplantation is a promising therapy for tissue regeneration. Extracellular vesicles (EVs) released by MSCs act as their paracrine effectors by delivering proteins and genetic material to recipient cel
Externí odkaz:
https://doaj.org/article/a7651fa5d5554882a57d774f46c05b8e
Autor:
Alfonso Eirin, Behzad Ebrahimi, Soon Hyo Kwon, Justin A. Fiala, Barbara J. Williams, John R. Woollard, Quan He, Ramech C. Gupta, Hani N. Sabbah, Y.S. Prakash, Stephen C. Textor, Amir Lerman, Lilach O. Lerman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)
BackgroundRenovascular hypertension (RVH) impairs cardiac structure and left ventricular (LV) function, but whether mitochondrial injury is implicated in RVH‐induced myocardial damage and dysfunction has not been defined. We hypothesized that cardi
Externí odkaz:
https://doaj.org/article/fe23883890a943bdb36304f66bcb2a68
Autor:
Timucin Taner, Amir Lerman, John R. Woollard, Hui Tang, Lilach O. Lerman, James D. Krier, Turun Song, Kyra L. Jordan, Yu Zhao, Xiangyang Zhu, Alfonso Eirin
Publikováno v:
Hypertension
Metabolic syndrome (MetS) profoundly changes the contents of mesenchymal stem cells and mesenchymal stem cells–derived extracellular vesicles (EVs). The anti-inflammatory TGF-β (transforming growth factor-β) is selectively enriched in EVs from Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4889c9977a5b791b01616535a6b27072
https://doi.org/10.1161/hypertensionaha.119.14546
https://doi.org/10.1161/hypertensionaha.119.14546