Zobrazeno 1 - 10
of 64
pro vyhledávání: '"R, Widom"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
A single molecule fluorescence study revealed three dynamically interconverting conformations of the fluoride riboswitch from Bacillus cereus, where an anionic ligand snap-locks a docked conformation through a long-range interaction necessary for dow
Externí odkaz:
https://doaj.org/article/6b22dab2d431435caa34baf4000945a7
Publikováno v:
Biophysical Journal. 122:1600-1612
Base-Stacking Heterogeneity in RNA Resolved by Fluorescence-Detected Circular Dichroism Spectroscopy
Autor:
Julia R. Widom, Janson E. Hoeher
Publikováno v:
The Journal of Physical Chemistry Letters. 13:8010-8018
RNA plays a critical role in many biological processes, and the structures it adopts are intimately linked to those functions. Among many factors that contribute to RNA folding, van der Waals interactions between adjacent nucleobases stabilize struct
Riboswitches are gene-regulating mRNA segments most commonly found in bacteria. A riboswitch contains an aptamer domain that binds to a ligand, causing a conformational change in a downstream expression platform. The aptamer domain of the Class I pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf901728b526f2c07a49c04a41dd934f
https://doi.org/10.1101/2021.07.22.453416
https://doi.org/10.1101/2021.07.22.453416
Publikováno v:
RNA. 25:1457-1469
The ability to control transcription in a time-dependent manner in vitro promises numerous applications in molecular biology and nanotechnology. Here we demonstrate an approach that enables precise, independent control over the production of multiple
Publikováno v:
Biophysical Journal. 121:208a
Autor:
Corina Maeder, Nicholas Pittner, Nils G. Walter, Elizabeth Duran, Camille Potts, Julia R. Widom, Rachel Goldstein
Publikováno v:
The FASEB Journal. 33
Autor:
Janson E. Hoeher, Julia R. Widom
Publikováno v:
Biophysical Journal. 120:312a
Publikováno v:
Biophysical Journal. 120:287a
Publikováno v:
New Journal of Physics, Vol 15, Iss 2, p 025028 (2013)
We have observed the conformation-dependent electronic coupling between the monomeric subunits of a dinucleotide of 2-aminopurine (2-AP), a fluorescent analogue of the nucleic acid base adenine. This was accomplished by extending two-dimensional fluo
Externí odkaz:
https://doaj.org/article/ec5ee1a9034c43369752571a83a92232