Výsledky vyhledávání

The anti-HIV pentameric pseudopeptide HB-19 is preferentially taken up in vivo by lymphoid organs where it forms a complex with nucleolin

Autor: Ara G. Hovanessian, R. Vienet, Bernard Krust, Lena Edelman, Christian Callebaut, J. M. Grognet, J. P. Briand, Etienne Jacotot, Gilles Guichard, Catherine Rougeot, A. Cardona

Publikováno v: Proceedings of the National Academy of Sciences. 98:14090-14095

The HB-19 pseudopeptide 5[Kψ(CH 2 N)PR]-TASP, ψ(CH 2 N) for reduced peptide bond, is a specific inhibitor of HIV infection in different CD4 + cell lines and in primary T-lymphocytes and macrophages. It blocks virus-particle attachment to permissive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacb6658acc63a7459928ea6ca2e4c84
https://doi.org/10.1073/pnas.221467298

Zobrazit plný text záznamu

A new specific enzyme immunoassay allowing an efficient pharmacokinetic evaluation of gamma-cyclodextrin after intravenous administration to rats

Autor: C, Créminon, F, Djedaïni-Pilard, R, Vienet, C, Péan, J M, Grognet, J, Grassi, B, Perly, P, Pradelles

Publikováno v: Pharmaceutical research. 16(9)

Because of its ability to form complexes with drugs, gamma-cyclodextrin is of great potential value in pharmaceutical formulations. The biological fate of y-cyclodextrin must therefore be considered in safety evaluation, using sensitive and specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8bd2e20f9b67c1272050e95f12bfa64d
https://pubmed.ncbi.nlm.nih.gov/10496657

Zobrazit plný text záznamu

Development of Enzyme Immunoassays Specific for Natural ß- and γ-Cyclodextrins and Synthetic Derivatives. Pharmacokinetic Analysis of Cyclodextrins in Rat

Autor: J. Grassi, C. Créminon, R. Vienet, P. Pradelles, Florence Djedaïni-Pilard, B. Perly, C. Péan

Publikováno v: Proceedings of the Ninth International Symposium on Cyclodextrins ISBN: 9789401059718

Pharmacological applications of CDs are mainly based on an increase of the solubility of the active molecule entrapped. The development of pharmaceutical uses requires quantitative measurements of CD in biological material. We have developed differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d78fb09fadae091a5b44d7fe199b5d5f
https://doi.org/10.1007/978-94-011-4681-4_2

Zobrazit plný text záznamu

Targets for SMR1-pentapeptide suggest a link between the circulating peptide and mineral transport

Autor: L. Le Doledec, A. Cardona, J. M. Grognet, Catherine Rougeot, R. Vienet, F. Rougeon

Publikováno v: The American journal of physiology. 273(4)

The submandibular rat 1 protein (SMR1) is selectively processed at pairs of basic amino acid residues in a tissue- and sex-specific manner. We have mapped peripheral targets for the final secretory maturation product of SMR1, the pentapeptide QHNPR,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935776c5843d0d9d6326804e09e2b8f4
https://pubmed.ncbi.nlm.nih.gov/9362294

Zobrazit plný text záznamu

Metabolite involvement in bromocriptine-induced prolactin inhibition in rats

Autor: D, Valente, M, Delaforge, S, Urien, D, Guivarc'h, R, Vienet, J M, Grognet, E, Ezan

Publikováno v: The Journal of pharmacology and experimental therapeutics. 282(3)

Bromocriptine (BCT) is a dopamine D2 receptor agonist used for the treatment of Parkinson's disease and hyperprolactinemic disorders. After oral administration, BCT is metabolized into mono- or dihydroxylated metabolites. To study how these metabolit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::684d394e60a4136f138df802de1792f0
https://pubmed.ncbi.nlm.nih.gov/9316855

Zobrazit plný text záznamu

Orion project: acceleration of ion clusters and highly charged biomolecules from 10 MeV to 1 GeV

Autor: J.D. Larson, R. Vienet-Legué, P. Attal, D. Gardes, Y. Le Beyec, B. Waast, Serge Della-Negra

Publikováno v: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Nuclear Instruments and Methods in Physics Research A
International Conference On Electrostatic Accelerators And Associated Boosters.6
International Conference On Electrostatic Accelerators And Associated Boosters.6, Jun 1992, Padova, Italy. pp.293-299

To allow the acceleration of beams of metallic clusters and biomolecules up to MeV energies, modifications were made to the MP9 tandem in Orsay. An ion source and the beam injection line will be available in the terminal, a tube section of the proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b551e449453567aa9ce1b7ccfaf9f6fb
http://hal.in2p3.fr/in2p3-00014769

Zobrazit plný text záznamu

Development and in vivo assessment of a transdermal system for physostigmine

Autor: F. Fouchart, M. Vincenti, R. Vienet, Alain Pruvost, M. Istin, Jean-Marc Grognet, Henri Benech

Publikováno v: Methods and Findings in Experimental and Clinical Pharmacology. 20:489

A copolymer was developed as a transdermal (TD) system for physostigmine. The loading was carried out with a solution of physostigmine (PHY) base (20 mg/ml) in water/ethanol: 80/20 (v/v) at 40 degrees C for 3 h. The PHY load was 5.3 mg/cm2 (n = 3). D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8058ce0d308b7ed9276bfae125cf35c2
https://doi.org/10.1358/mf.1998.20.6.485712

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání