Zobrazeno 1 - 10
of 76
pro vyhledávání: '"R, Toal"'
Autor:
Adam D Kennedy, Lisa Ford, Bryan Wittmann, Jesse Conner, Jacob Wulff, Matthew Mitchell, Anne M Evans, Douglas R Toal
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249797 (2021)
IntroductionAnalysis of blood for the evaluation of clinically relevant biomarkers requires precise collection and sample handling by phlebotomists and laboratory staff. An important consideration for the clinical application of metabolomics are the
Externí odkaz:
https://doaj.org/article/e2d1db67b3934997bbe2525e1c2b71fa
Autor:
N. Fuhr, S. Zhou, K. Shen, A. Rajab, S. Es-Said, S. Thaung, S. Tan, R. Riebe, N. Santos, Y. Thura Hein, R. Toal, Y. Li, M. Timko, O. S. Es-Said
Publikováno v:
Journal of Engineering Materials and Technology. 145
This study compares the fatigue performance between the AA2050-T852 alloy and AA7050-T7452 alloy traditionally used in aircraft structures. Rotating beam fatigue tests were performed on AA2050-T852 and AA7050-T7452 specimens cut from forged plates wi
Autor:
Lisa A. Ford, Bryan Wittmann, Luke A. D. Miller, Kelli Goodman, Anne M. Evans, Douglas R. Toal, Adam D. Kennedy, Matthew W. Mitchell
Publikováno v:
Metabolomics. 17
Clinical metabolomics has utility as a screen for inborn errors of metabolism (IEM) and variant classification in patients with rare disease. It is important to understand and characterize preanalytical factors that influence assay performance during
Autor:
Luke A. D. Miller, Douglas R. Toal, Kirk L. Pappan, Bobby R Wiggs, Kelli Goodman, Adam D. Kennedy, Sarah H. Elsea, John J Lennon, Anne M. Evans, Lisa A. Ford, Jacob Wulff
Publikováno v:
The journal of applied laboratory medicine. 5(2)
Background The application of whole-exome sequencing for the diagnosis of genetic disease has paved the way for systems-based approaches in the clinical laboratory. Here, we describe a clinical metabolomics method for the screening of metabolic disea
Autor:
Douglas R. Toal, Lisa A. Ford, Anne M. Evans, Bryan Wittmann, Jesse Conner, Adam D. Kennedy, Jacob Wulff, Matthew D. Mitchell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249797 (2021)
PLoS ONE, Vol 16, Iss 4, p e0249797 (2021)
Introduction Analysis of blood for the evaluation of clinically relevant biomarkers requires precise collection and sample handling by phlebotomists and laboratory staff. An important consideration for the clinical application of metabolomics are the
Identification of an Endogenous Organosulfur Metabolite by Interpretation of Mass Spectrometric Data
Publikováno v:
Organic letters. 20(7)
The chemical structure of x11564, a new endogenous organosulfur metabolite, was elucidated by de novo interpretation of mass spectrometric data. The structure was confirmed by comparison to a synthetic standard. Metabolite x11564 is structurally rela
Autor:
G. Terrance Walker, Julia Quan, Kelly L. Frye, Tony J. Rockweiler, Douglas R. Toal, Susan R. Mitchner, Rossio K. Kersey
Publikováno v:
Clinical Microbiology Newsletter. 37:169-173
Antibiotic-resistant bacteria threaten the well-being of many hospitalized patients and cause an added financial burden on health care systems. There is a particular challenge in identification of the antimicrobial-resistance phenotype for Gram-negat
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Publikováno v:
Metabolomics
Introduction A major bottleneck in metabolomic studies is metabolite identification from accurate mass spectrometric data. Metabolite x17299 was identified in plasma as an unknown in a metabolomic study using a compound-centric approach where the ass
Autor:
Kate E.T. Vroom, Jessie K. Conner, Deirdre M. Hauser, Kelli Goodman, Qibo Zhang, Douglas R. Toal, Tiffany Freed, Lisa A. Ford
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
Early detection of insulin resistance (IR) and/or impaired glucose tolerance (IGT) is crucial for delaying and preventing the progression toward type 2 diabetes. We recently developed and validated a straightforward metabolite-based test for the asse