Zobrazeno 1 - 10
of 2 143
pro vyhledávání: '"R, Steinberg"'
Autor:
Nathaniel A. Swift, Qian Yang, Hannah M. Jester, Xueyan Zhou, Adam Manuel, Bruce E. Kemp, Gregory R. Steinberg, Tao Ma
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106664- (2024)
AMP-activated protein kinase (AMPK) is an αβγ heterotrimer protein kinase that functions as a molecular sensor to maintain energy homeostasis. Accumulating evidence suggests a role of AMPK signaling in the regulation of synaptic plasticity and cog
Externí odkaz:
https://doaj.org/article/7fa0064dd409485ab3e1e18d09af9746
Autor:
Jordan S.F. Chan, Seyed Amirhossein Tabatabaei Dakhili, Maria Areli Lorenzana-Carrillo, Keshav Gopal, Serena M. Pulente, Amanda A. Greenwell, Kunyan Yang, Christina T. Saed, Magnus J. Stenlund, Sally R. Ferrari, Indiresh A. Mangra-Bala, Tanin Shafaati, Rakesh K. Bhat, Farah Eaton, Michael Overduin, Sebastian Beck Jørgensen, Gregory R. Steinberg, Erin E. Mulvihill, Gopinath Sutendra, John R. Ussher
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114573- (2024)
Summary: Growth differentiation factor 15 (GDF15) is a peptide with utility in obesity, as it decreases appetite and promotes weight loss. Because obesity increases the risk for type 2 diabetes (T2D) and cardiovascular disease, it is imperative to un
Externí odkaz:
https://doaj.org/article/8e982b3f2425453094ab8152492fec0a
Autor:
Claudio Pulito, Federica Mori, Andrea Sacconi, Frauke Goeman, Maria Ferraiuolo, Patrizia Pasanisi, Carlo Campagnoli, Franco Berrino, Maurizio Fanciulli, Rebecca J. Ford, Massimo Levrero, Natalia Pediconi, Ludovica Ciuffreda, Michele Milella, Gregory R. Steinberg, Mario Cioce, Paola Muti, Sabrina Strano, Giovanni Blandino
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/501e7d37afcc4aa583a480148d920162
Autor:
Julia H. Littell, Sarah Young, Therese D. Pigott, M. Antonia Biggs, Trine Munk‐Olsen, Julia R. Steinberg
Publikováno v:
Campbell Systematic Reviews, Vol 20, Iss 2, Pp n/a-n/a (2024)
Abstract This is a protocol for a systematic review and meta‐analysis of research on mental health outcomes of abortion. Does abortion increase the risk of adverse mental health outcomes? That is the central question for this review. Our review aim
Externí odkaz:
https://doaj.org/article/d52c5a60649346868a563eca0e9474de
Autor:
Olga‐Demetra Biziotis, Evangelia Evelyn Tsakiridis, Amr Ali, Elham Ahmadi, Jianhan Wu, Simon Wang, Bassem Mekhaeil, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Bassam Abdulkarim, Ranjan K. Sur, Aruz Mesci, Peter Ellis, Tobias Berg, Jonathan L Bramson, Paola Muti, Gregory R Steinberg, Theodoros Tsakiridis
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2235-2256 (2023)
Non‐small cell lung cancer (NSCLC) has a poor prognosis, and effective therapeutic strategies are lacking. The diabetes drug canagliflozin inhibits NSCLC cell proliferation and the mammalian target of rapamycin (mTOR) pathway, which mediates cell g
Externí odkaz:
https://doaj.org/article/fdf11bf69eda42b6b882eebd1bdee6ce
Autor:
Amr Ali, Bassem Mekhaeil, Olga-Demetra Biziotis, Evangelia E. Tsakiridis, Elham Ahmadi, Jianhan Wu, Simon Wang, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Aruz Mesci, Stanley Liu, Tobias Berg, Jonathan L. Bramson, Gregory R. Steinberg, Theodoros Tsakiridis
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-21 (2023)
Abstract Radiotherapy is a non-invasive standard treatment for prostate cancer (PC). However, PC develops radio-resistance, highlighting a need for agents to improve radiotherapy response. Canagliflozin, an inhibitor of sodium-glucose co-transporter-
Externí odkaz:
https://doaj.org/article/9c7aa81371a04cb8923c5385d902ad3c
Autor:
Emily A. Day, Logan K. Townsend, Sonia Rehal, Battsetseg Batchuluun, Dongdong Wang, Marisa R. Morrow, Rachel Lu, Lucie Lundenberg, Jessie H. Lu, Eric M. Desjardins, Tyler K.T. Smith, Amogelang R. Raphenya, Andrew G. McArthur, Morgan D. Fullerton, Gregory R. Steinberg
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108269- (2023)
Summary: Atherosclerotic cardiovascular disease is characterized by both chronic low-grade inflammation and dyslipidemia. The AMP-activated protein kinase (AMPK) inhibits cholesterol synthesis and dampens inflammation but whether pharmacological acti
Externí odkaz:
https://doaj.org/article/3e71dfd38cb24b0fa08de9d413beeee1
Autor:
Samantha G. Farris, Jacqueline E. Smith, Dana R. Steinberg, Brianna R. Altman, Geralyn M. Lambert-Messerlian, Shira I. Dunsiger, David M. Williams, Michael E. Saladin, Ana M. Abrantes
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Two primary ovarian hormones that fluctuate across the female menstrual cycle—estradiol and progesterone—have been independently linked in separate literatures to nicotine reinforcement and anxiety psychopathology. We identify existing methodolog
Externí odkaz:
https://doaj.org/article/c0009268e2364130a30d287b4854069a
Autor:
Yun Han Kwon, Suhrid Banskota, Huaqing Wang, Laura Rossi, Jensine A. Grondin, Saad A. Syed, Yeganeh Yousefi, Jonathan D. Schertzer, Katherine M. Morrison, Michael G. Wade, Alison C. Holloway, Michael G. Surette, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Chemicals in food are widely used leading to significant human exposure. Allura Red AC (AR) is a highly common synthetic colorant; however, little is known about its impact on colitis. Here, we show chronic exposure of AR at a dose found in
Externí odkaz:
https://doaj.org/article/e22bc7fbc4f04c989edfbdc65e3e4ed2