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pro vyhledávání: '"R, Staunton"'
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences. 116:14448-14455
Mechanical homeostasis describes how cells sense physical cues from the microenvironment and concomitantly remodel both the cytoskeleton and the surrounding extracellular matrix (ECM). Such feedback is thought to be essential to healthy development a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6784ce2d59e5043d5357abdea114d617
https://doi.org/10.1073/pnas.1814271116
https://doi.org/10.1073/pnas.1814271116
Autor:
Alexus Devine, Chaunte Lewis, Zheng-gang Liu, Kevin Bishop, Raman Sood, Hannah A. Burr, William J. Wulftange, Kandice Tanner, Jack R. Staunton, Kathryn M. Daly, Qing Xu, Colin D. Paul, Swati Choksi, Daniel S. Green
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
The inflammatory response, modulated both by tissue resident macrophages and recruited monocytes from peripheral blood, plays a critical role in human diseases such as cancer and neurodegenerative disorders. Here, we sought a model to interrogate hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa40d1a3769ff07093641d341378dd3
http://link.springer.com/article/10.1038/s41598-018-38186-y
http://link.springer.com/article/10.1038/s41598-018-38186-y
Akademický článek
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Publikováno v:
Biomaterials
Variation in matrix elasticity has been shown to determine cell fate in both differentiation and development of malignant phenotype. The tissue microenvironment provides complex biochemical and biophysical signals in part due to the architectural het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d141776085f8b3c5eca2999c552ab8
https://doi.org/10.1016/j.biomaterials.2015.12.019
https://doi.org/10.1016/j.biomaterials.2015.12.019
Publikováno v:
Optics express. 25(3)
In optical trapping, accurate determination of forces requires calibration of the position sensitivity relating displacements to the detector readout via the V-nm conversion factor (β). Inaccuracies in measured trap stiffness (k) and dependent calcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bb9519e0476ef274569393e22b61e5
https://pubmed.ncbi.nlm.nih.gov/29519028
https://pubmed.ncbi.nlm.nih.gov/29519028
Autor:
Kevin Bishop, Kandice Tanner, Lisa M. Miller Jenkins, Nicole Y. Morgan, Sarah M. Thomas, Elliott L. Paine, Raman Sood, Alexus Devine, Colin D. Paul, Jack R. Staunton
Sites of metastasis are non-random, with certain types of cancers showing organ preference during distal colonization. Using multiple brain- and bone marrow-seeking human and murine breast cancer subclones, we determined that tumor cells that home to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2852220787b66ce083e39cf98e6d5f
https://doi.org/10.1101/233361
https://doi.org/10.1101/233361
Autor:
Colin D. Paul, Nancy Jiang, Jiyun Kim, Jack R. Staunton, Kandice Tanner, Kathryn M. Daly, Alex Hruska, Hannah A. Burr
Biophysical aspects of in vivo tissue microenvironments include microscale mechanical properties, fibrillar alignment, and architecture or topography of the extracellular matrix (ECM). These aspects act in concert with chemical signals from a myriad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef351613b0c9f26a42cc4946f9b50e1
https://doi.org/10.1101/232066
https://doi.org/10.1101/232066
Publikováno v:
Advanced Materials (Deerfield Beach, Fla.)
Biomimetic extracellular matrix (ECM) topographies driven by the magnetic‐field‐directed self‐assembly of ECM protein‐coated magnetic beads are fabricated. This novel bottom‐up method allows us to program isotropic, anisotropic, and diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a85a06da35f9a5acbd46a8f8460588d
https://doi.org/10.1002/adma.201503950
https://doi.org/10.1002/adma.201503950
Publikováno v:
Journal of Viral Hepatitis
Summary Hepatitis C virus (HCV) is a major and growing public health concern. We need to know the expected health burden and treatment cost, and understand uncertainty in those estimates, to inform policymaking and future research. Two models that ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d343bc89cefcb61bd219cff237bfb826
https://pubmed.ncbi.nlm.nih.gov/29274178
https://pubmed.ncbi.nlm.nih.gov/29274178