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Publikováno v:
Journal of Lipid Research, Vol 37, Iss 12, Pp 2525-2538 (1996)
The activity of lysosomal sphingolipid hydrolases is usually estimated in vitro from complex assays on cell lysates under artificial conditions including the presence of detergents and substrate analogs. However, the measure of their effective activi
Externí odkaz:
https://doaj.org/article/8e4042a9c3584f6eb6eecfe5e4c5eba2
Autor:
P, Guerby, F, Vidal, S, Garoby-Salom, C, Vayssiere, R, Salvayre, O, Parant, A, Negre-Salvayre
Publikováno v:
Gynecologie, obstetriquefertilite. 43(11)
Preeclampsia is a leading cause of pregnancy complications and affects 3-7% of pregnant women. Pathophysiology of preeclampsia is still unclear. According to the two-stage model of preeclampsia, the abnormal and hypoperfused placenta (stage 1) releas
This book presents the proceedings of the meeting on'Lipid Storage Disorders'which took place in Toulouse, France, in September 14-18, 1987 and which was set up as a joint NATO Advanced Research Workshop and INSERM International Symposium. The meetin
Autor:
D Graber, Thierry Levade, V. Flurin, J P Carrière, M F Testut, M. T. Pieraggi, R Salvayre, M B Delisle
Publikováno v:
Annals of Neurology. 35:116-119
Human beta-mannosidosis is an inherited lysosomal storage disorder described in only seven families. We present a further case in a black African 14-year-old boy with severely deficient beta-mannosidase activity, bilateral thenar and hypothenar amyot
Autor:
G. Dedieu, J. L. Montastruc, J. P. Thouvenot, Haleh Bagheri, J. F. Tournamille, Maryse Lapeyre-Mestre, Patrice Massip, A. Dugué, R. Salvayre, Laurent Sailler
Publikováno v:
Scopus-Elsevier
The awareness of muscular adverse drug reactions (ADRs) increased since the withdrawal of cerivastatin, a HMG-CoA reductase inhibitor, from the market in August 2001. Our objectives were to assess the detection and incidence of muscular ADRs in a Uni
Autor:
A. Galinier, M. Ecoiffier, C. Cinq-Frais, M. Bernard, P. Ritz, M. Tubéry, L. Astudillo, P. Arlet, C. Porquet, R. Salvayre
Publikováno v:
Nutrition Clinique et Métabolisme. 25:S94-S95
Publikováno v:
British journal of pharmacology. 132(8)
Oxidized low density lipoproteins (oxLDL) are thought to play a major role in atherosclerosis. OxLDL act in part through alteration of intracellular signalling pathways in cells of the vascular wall. We recently reported that the EGF receptor (EGFR)
Publikováno v:
Journal of chromatography. A. 895(1-2)
In recent papers, we presented a new analytical method for thiol quantification in serum. It is based on the use of capillary electrophoresis and laser-induced fluorescence to analyze thiol 6-iodoacetamidofluoresceine (IAF) derivatives. Quantitative
Publikováno v:
Chemistry and physics of lipids. 102(1-2)
The ubiquitous sphingophospholipid sphingomyelin (SM) can be hydrolysed in human cells to ceramide by different sphingomyelinases (SMases). These enzymes exert a dual role, enabling not only the turnover of membrane SM and the degradation of exogenou