Zobrazeno 1 - 10
of 127
pro vyhledávání: '"R, Salovaara"'
Publikováno v:
International Journal of Legal Medicine. 116:43-46
Massive haemorrhage due to rupture of single pancreatic or peripancreatic vessels is a very rare but potentially lethal complication of acute and chronic pancreatitis. The splenic, gastroduodenal, and pancreatoduodenal arteries are the more commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b5b92f30b40d605ff246f3feef4b82
https://doi.org/10.1007/s004140100247
https://doi.org/10.1007/s004140100247
Autor:
W, Müller, L J, Burgart, R, Krause-Paulus, S N, Thibodeau, M, Almeida, T B, Edmonston, C R, Boland, C, Sutter, J R, Jass, A, Lindblom, J, Lubinski, K, MacDermot, D S, Sanders, H, Morreau, A, Müller, C, Oliani, T, Orntoft, M, Ponz De Leon, C, Rosty, M, Rodriguez-Bigas, J, Rüschoff, A, Ruszkiewicz, J, Sabourin, R, Salovaara, G, Möslein
Publikováno v:
Familial cancer. 1(2)
Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is an autosomal dominant condition accounting for 2-5% of all colorectal carcinomas as well as a small subset of endometrial, upper urinary tract and other gastrointestinal cancers. An assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::741f283432730bb0363f4d8d3afb4d09
https://pubmed.ncbi.nlm.nih.gov/14574003
https://pubmed.ncbi.nlm.nih.gov/14574003
Autor:
H, Nakagawa, G J, Nuovo, E E, Zervos, E W, Martin, R, Salovaara, L A, Aaltonen, A, de la Chapelle
Publikováno v:
Cancer research. 61(19)
Hypermethylation of the MLH1 promoter underlies most sporadic colorectal cancers with microsatellite instability (MSI). To investigate the role of hypermethylation in the normal colonic mucosa as a possible precursor lesion, we studied 700 bp upstrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dfa3701407612d4111df1d885f6bd56
https://pubmed.ncbi.nlm.nih.gov/11585722
https://pubmed.ncbi.nlm.nih.gov/11585722
Autor:
A, Loukola, K, Eklin, P, Laiho, R, Salovaara, P, Kristo, H, Järvinen, J P, Mecklin, V, Launonen, L A, Aaltonen
Publikováno v:
Cancer research. 61(11)
Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant cancer predisposition syndrome caused by germ-line mutations in DNA mismatch repair genes. It is relevant to identify HNPCC patients because colonoscopic screening of individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ef0f4a15e5888dadbdf721090692d30
https://pubmed.ncbi.nlm.nih.gov/11389088
https://pubmed.ncbi.nlm.nih.gov/11389088
Autor:
P, Schweizer, A L, Moisio, S A, Kuismanen, K, Truninger, R, Vierumäki, R, Salovaara, J, Arola, R, Butzow, J, Jiricny, P, Peltomäki, M, Nyström-Lahti
Publikováno v:
Cancer research. 61(7)
Hereditary nonpolyposis colorectal cancer syndrome is associated with an inherited predisposition to primarily colorectal cancer (CRC) and endometrial cancer (EC); however, the biological basis of the organ involvement remains unknown. As an attempt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5b68748eeba4c09fa2c9177db46db9f
https://pubmed.ncbi.nlm.nih.gov/11306449
https://pubmed.ncbi.nlm.nih.gov/11306449
Autor:
V, Launonen, E, Avizienyte, A, Loukola, P, Laiho, R, Salovaara, H, Järvinen, J P, Mecklin, A, Oku, M, Shimane, H C, Kim, J C, Kim, J, Nezu, L A, Aaltonen
Publikováno v:
Cancer research. 60(3)
LKB1 serine/threonine kinase is a gene for Peutz-Jeghers cancer predisposition syndrome. Most studies have detected a low frequency of LKB1 defects in sporadic cancer. A notable exception is a recent report describing frequent, mostly missense type,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8fb71b70d0b2adf11e3dac73117680c
https://pubmed.ncbi.nlm.nih.gov/10676634
https://pubmed.ncbi.nlm.nih.gov/10676634
Autor:
M, Nyström-Lahti, M, Holmberg, P, Fidalgo, R, Salovaara, A, de la Chapelle, J, Jiricny, P, Peltomäki
Publikováno v:
Genes, chromosomescancer. 26(4)
Germline mutations that give rise to premature termination codons in mRNAs have frequently been associated with aberrant processing of the nascent transcripts. This can take the form either of nonsense-mediated mRNA decay or of aberrant splicing of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::632a3c0ad0b01b2914e3590a5b29d4dc
https://pubmed.ncbi.nlm.nih.gov/10534773
https://pubmed.ncbi.nlm.nih.gov/10534773
Autor:
M, Aarnio, R, Sankila, E, Pukkala, R, Salovaara, L A, Aaltonen, A, de la Chapelle, P, Peltomäki, J P, Mecklin, H J, Järvinen
Publikováno v:
International journal of cancer. 81(2)
Excessive incidence of various cancers is a challenging feature of the hereditary-non-polyposis-colorectal-cancer (HNPCC) syndrome. This study estimated the cancer incidences in HNPCC compared with the general population. Individuals in a cohort of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8930d8410898406572dcddc887937672
https://pubmed.ncbi.nlm.nih.gov/15214315
https://pubmed.ncbi.nlm.nih.gov/15214315
Autor:
J L, Tsao, J, Zhang, R, Salovaara, Z H, Li, H J, Järvinen, J P, Mecklin, L A, Aaltonen, D, Shibata
Publikováno v:
The American journal of pathology. 153(4)
Occult aspects of tumor proliferation are likely recorded genetically as their microsatellite (MS) loci become polymorphic. However, MS mutations generated by division may also be eliminated with death as noncoding MS loci lack selective value. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::134177e561f88204af8e4db751bc4f7a
https://pubmed.ncbi.nlm.nih.gov/9777950
https://pubmed.ncbi.nlm.nih.gov/9777950
Publikováno v:
International journal of cancer. 74(5)
To identify characteristics of gastric cancer associated with hereditary non-polyposis colorectal cancer (HNPCC), we gathered clinical data and tumor samples relating to patients recorded in the Finnish HNPCC registry. Our series included 51 families
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::513806e6fdb41decd2e1d0c32942e552
https://pubmed.ncbi.nlm.nih.gov/9355980
https://pubmed.ncbi.nlm.nih.gov/9355980