Zobrazeno 1 - 10
of 7 881
pro vyhledávání: '"R, Parker"'
Autor:
Alexis R. Steinmetz, Morgan Pierce, Alberto Martini, Come Tholomier, Ganiraju Manyam, Yan Chen, Akshay Sood, Jonathan J. Duplisea, Burles A. Johnson, Bogdan A. Czerniak, Byron H. Lee, Chinnaswamy Jagannath, Seppo Yla-Herttuala, Nigel R. Parker, David J. McConkey, Colin P. Dinney, Sharada Mokkapati
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNadofaragene firadenovec (Ad-IFNα/Syn3) is now approved for BCG-unresponsive bladder cancer (BLCA). IFNα is a pleiotropic cytokine that causes direct tumor cell killing via TRAIL-mediated apoptosis, angiogenesis inhibition, and activati
Externí odkaz:
https://doaj.org/article/63a622d2fe494a5898ec7dc003c1d01b
Autor:
Parker J. Ellingson, Yousif O. Shams, Jessica R. Parker, Ronald L. Calabrese, Gennady S. Cymbalyuk
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
For animals to meet environmental challenges, the activity patterns of specialized oscillatory neural circuits, central pattern generators (CPGs), controlling rhythmic movements like breathing and locomotion, are adjusted by neuromodulation. As a rep
Externí odkaz:
https://doaj.org/article/46483948919849a7a2ed9c6acb33db53
Autor:
Sydney J. Conner, Justinne R. Guarin, Thanh T. Le, Jackson P. Fatherree, Charlotte Kelley, Samantha L. Payne, Savannah R. Parker, Hanan Bloomer, Crystal Zhang, Kenneth Salhany, Rachel A. McGinn, Emily Henrich, Anna Yui, Deepti Srinivasan, Hannah Borges, Madeleine J. Oudin
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Metastasis is the leading cause of death in breast cancer patients. For metastasis to occur, tumor cells must invade locally, intravasate, and colonize distant tissues and organs, all steps that require tumor cell migration. The m
Externí odkaz:
https://doaj.org/article/7a4e67d5306d4959bd38e1ceb19aa28a
Autor:
Edward M.C. Courvan, Roy R. Parker
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114452- (2024)
Summary: Macrophages are effector immune cells that experience substantial changes to oxygenation when transiting through tissues, especially when entering tumors or infected wounds. How hypoxia alters gene expression and macrophage effector function
Externí odkaz:
https://doaj.org/article/284e43e102c84a05bbc789cc43d41c25
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background We previously performed a systematic review and meta-analysis which revealed a Phantom Limb Pain (PLP) prevalence estimate of 64% [95% CI: 60.01–68.1]. The prevalence estimates varied significantly between developed and developi
Externí odkaz:
https://doaj.org/article/834315ad44d042488c44f8d292558dc6
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Oropharyngeal cancer (OPC) poses a complex therapeutic dilemma for patients and oncologists alike, made worse by the epidemic increase in new cases associated with the oncogenic human papillomavirus (HPV). In a counterintuitive manner, the very thing
Externí odkaz:
https://doaj.org/article/8ea2547eee93435b9b63c357b87290bd
Autor:
Andrew R. Parker
Publikováno v:
Records of the Australian Museum, Vol 75, Iss 4, Pp 515-517 (2023)
In the deep sea, it is unknown how eyes that use concave mirrors to focus can distinguish between the small bioluminescent lights of their prey and those larger lights of more distant predators. Beyond 1000 m depth, where sunlight is no longer percep
Externí odkaz:
https://doaj.org/article/bad76c0419ec4132bb3e3d33d976f8d6
Autor:
Sija Sajibu, Emanuel Sonder, Amit Tiwari, Stephany Orjuela, Hannah R. Parker, Olivier The Frans, Christoph Gubler, Giancarlo Marra, Mark D. Robinson
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background We previously identified 16,772 colorectal cancer-associated hypermethylated DNA regions that were also detectable in precancerous colorectal lesions (preCRCs) and unrelated to normal mucosal aging. We have now conducted a study t
Externí odkaz:
https://doaj.org/article/95ec007978e74dc5b478fee130f12817
Autor:
Stirland, Isaac, Soares, Murilo Racy, Furtado, Cristiana Libardi Miranda, Dos Reis, Rosana Maria, Aston, Kenneth I., Smith, R. Parker, Jenkins, Timothy G.
Publikováno v:
In F&S Science February 2024 5(1):2-15
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 8429-8452 (2023)
We use the GEOS-Chem global 3-D model and two inverse methods (the maximum a posteriori and ensemble Kalman filter) to infer regional methane (CH4) emissions and the corresponding stable-carbon-isotope source signatures from 2004–2020 across the gl
Externí odkaz:
https://doaj.org/article/f533d6bea0d349deb4c76aa7fcb97ff7