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Autor:
O. Pillai, R. Panchagnula
Publikováno v:
Journal of Controlled Release. 88:287-296
The delivery of large peptides through the skin poses a significant challenge, and various strategies are under active investigation for enhancing the transdermal permeation. For large peptides, it is difficult to achieve significant permeation using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702b91d2816b27d1d8c50f60da181c81
https://doi.org/10.1016/s0168-3659(03)00065-8
https://doi.org/10.1016/s0168-3659(03)00065-8
Autor:
R. Panchagnula, C. S. Dey
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 22:7-19
The objective of drug targeting is to deliver drugs to a specific site of action through a carrier system. In cancer chemotherapy, cytotoxic drugs kill cancerous cells but also damage normal cells. Monoclonal antibodies generated against specific ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91077e6e1aab910a1873d540b5b230e
https://doi.org/10.1046/j.1365-2710.1997.96475964.x
https://doi.org/10.1046/j.1365-2710.1997.96475964.x
Autor:
S. Chari, R. Panchagnula
Publikováno v:
International Broadcasting Convention (IBC) 2013 Conference.
Delivery of video using Adaptive Bit Rate (ABR) streaming requires creating multiple representations of the same input video at different profiles encoded at different bitrates, frame rates and/or spatial resolutions. Selection of these profiles is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b21b2017ce8feb8a560e771bc220b9fe
https://doi.org/10.1049/ibc.2013.0040
https://doi.org/10.1049/ibc.2013.0040
Autor:
Anders Vahlquist, John J. Voorhees, E.M.G.J. de Jong, A. Buntinx, Douglas F. Gibbs, B. Friedman, Ethel Tur, Eva Stenström, James Varani, C.O. Bull, Paul L. Stanley, P.C.M. van de Kerkhof, Eva Andersson, Richard H. Guy, Thomas Ruzicka, J.C.M. Scholte, Steiner Stephen A, Hans Törmä, Marie L. Landry, Elka Touitou, Mary Havens, Kenneth M. Tramposch, James A. Mezick, Robert J. Capetola, Gerard J. Gendimenico, M. Ashraf, Pauline M. Schwartz, R. Panchagnula, Petr Arenberger, I.M.M.J. van Vlijmen, Howard I. Maibach, Lajos Kemény, Biren Shah, W. Tanaka, K. Stemmer, W.A. Ritschel, L.M. Milstone, H. Reuveni, Francesca Levi-Schaffer
Publikováno v:
Skin Pharmacology and Physiology. 4:I-VI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684cf4ae33dd3c0e3160f012aa6d9d2a
https://doi.org/10.1159/000210954
https://doi.org/10.1159/000210954
Publikováno v:
Skin Pharmacology and Physiology. 4:235-245
In previous studies we reported that the permeation of dexamethasone and hydrocortisone across the skin was decreased and penetration into the skin was increased in the presence of Transcutol® (TC) when compared to water as a solvent. The objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f207babb0dab60538f4339ee509a1ee2
https://doi.org/10.1159/000210957
https://doi.org/10.1159/000210957
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 30(7)
Vehicles and permeation enhancers (PEs) used in transdermal drug delivery (TDD) of a drug can affect skin hydration, integrity and permeation of the solute administered. This investigation was designed to study the effect of the most commonly used ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dc270d8a0d1b5c65314d34a2c95394
https://pubmed.ncbi.nlm.nih.gov/18985178
https://pubmed.ncbi.nlm.nih.gov/18985178
Publikováno v:
Die Pharmazie. 63(6)
The currently existing treatment modalities of cancer suffer from a major drawback of systemic toxicity, which results from high systemic drug exposure. Delivery of chemotherapeutic agents by delivery systems that alleviate systemic side effects but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b7ef5b2907ef4ef07057e7c0efcdac4
https://pubmed.ncbi.nlm.nih.gov/18604987
https://pubmed.ncbi.nlm.nih.gov/18604987
Autor:
S, Khandavilli, R, Panchagnula
Publikováno v:
Die Pharmazie. 62(6)
The objective of this investigation was to develop and validate skin permeation methodology for a highly lipophilic drug with respect to sink conditions and intactness of barrier during the course of experiment, using water permeation and trans epide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6f9437fce6720d1541752a4e720bae8
https://pubmed.ncbi.nlm.nih.gov/17663199
https://pubmed.ncbi.nlm.nih.gov/17663199
Publikováno v:
Die Pharmazie. 61(12)
The present study focuses on the physical and chemical stability of insulin under iontophoretic conditions using HPLC, SDS-PAGE, RIA and biological assay. Influence of pH, concentration of insulin, current strength and duration of current application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6471d7a5e3d341633faf202b021d1681
https://pubmed.ncbi.nlm.nih.gov/17283659
https://pubmed.ncbi.nlm.nih.gov/17283659