Zobrazeno 1 - 10
of 135
pro vyhledávání: '"R, Nannini"'
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Breast cancer is the most common cancer diagnosed in women and is often treated with chemotherapy. Although previous studies have demonstrated increasing biological age in patients who receive chemotherapy, evaluation of this association with DNA met
Externí odkaz:
https://doaj.org/article/fd373f908b7e44d4b961837eafa15364
Autor:
Drew R. Nannini, Rene Cortese, Peter Egwom, Senthilnathan Palaniyandi, Gerhard C. Hildebrandt
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-8 (2023)
Abstract Chronic lymphocytic leukemia (CLL) is a mature B cell neoplasm with a predilection for older individuals. While previous studies have identified epigenetic signatures associated with CLL, whether age-related DNA methylation changes modulate
Externí odkaz:
https://doaj.org/article/13f798d1cf85400a900e08a789e82a78
Autor:
Konrad Teodor Sawicki, Drew R. Nannini, Suzette J. Bielinski, Nicholas B. Larson, Donald M. Lloyd-Jones, Bruce Psaty, Kent D. Taylor, Sanjiv J. Shah, Laura J. Rasmussen-Torvik, John T. Wilkins, Elizabeth M. McNally, Ravi B. Patel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Circulating protease inhibitors are important regulators of inflammation that are implicated in the pathophysiology of heart failure (HF). Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor which protects pulmonary
Externí odkaz:
https://doaj.org/article/aa784adc542245dba4ab31c8f58a617e
Autor:
Aakash Bavishi, Laura A. Colangelo, Laura J. Rasmussen‐Torvik, Joao A.C. Lima, Drew R. Nannini, Muthiah Vaduganathan, Ambarish Pandey, Donald M. Lloyd‐Jones, Sanjiv J. Shah, Ravi B. Patel
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 1496-1501 (2022)
Abstract Aims The effects of inhibition of sodium glucose cotransporter (SGLT)‐1, as opposed to SGLT2, on cardiovascular structure and function are not well known. We assessed the associations of a missense genetic variant of SGLT1 with cardiac str
Externí odkaz:
https://doaj.org/article/6059aaa6b0404b9fb94922af08c4dedc
Autor:
Feinuo Sun, Jie Yao, Shichao Du, Feng Qian, Allison A. Appleton, Cui Tao, Hua Xu, Lei Liu, Qi Dai, Brian T. Joyce, Drew R. Nannini, Lifang Hou, Kai Zhang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 5 (2023)
Background Existing studies on cardiovascular diseases (CVDs) often focus on individual‐level behavioral risk factors, but research examining social determinants is limited. This study applies a novel machine learning approach to identify the key p
Externí odkaz:
https://doaj.org/article/e0cbe78a248443d18a89546a9f99e093
Autor:
Olugbenga Akindele Silas, Fatimah Abdulkareem, Jorge Eduardo Novo, Yinan Zheng, Drew R. Nannini, Demirkan B. Gursel, Rose Anorlu, Jonah Musa, Firas H. Wehbe, Atiene S. Sagay, Folasade T. Ogunsola, Robert L. Murphy, Lifang Hou, Jian-Jun Wei
Publikováno v:
Annals of Global Health, Vol 88, Iss 1 (2022)
Inadequate pathology personnel and high cost of running a Pathology facility are factors affecting access to timely and quality pathology services in resource-constrained settings. Telepathology is a novel technology that allows Pathologists to remot
Externí odkaz:
https://doaj.org/article/2932d99f521340658c9d62bfa775811a
Autor:
Jonah Musa, Kyeezu Kim, Yinan Zheng, Yishu Qu, Brian T. Joyce, Jun Wang, Drew R. Nannini, Demirkan B. Gursel, Olugbenga Silas, Fatimah B. Abdulkareem, Godwin Imade, Alani S. Akanmu, Jian-Jun Wei, Masha Kocherginsky, Kwang-Youn A. Kim, Firas Wehbe, Chad J. Achenbach, Rose Anorlu, Melissa A. Simon, Atiene Sagay, Folasade T. Ogunsola, Robert L. Murphy, Lifang Hou
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundInvasive cervical cancer (ICC) is a serious public health burden in Nigeria, where human immunodeficiency virus (HIV) remains highly prevalent. Previous research suggested that epigenetic age acceleration (EAA) could play a role in detectio
Externí odkaz:
https://doaj.org/article/4189762c3c40486db8f9d0dfd114347b
Autor:
Supriya D. Mehta, Drew R. Nannini, Fredrick Otieno, Stefan J. Green, Walter Agingu, Alan Landay, Yinan Zheng, Lifang Hou
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT Bacterial vaginosis (BV) affects 20% of women worldwide and is associated with adverse reproductive health outcomes and increased risk for HIV. Typically, BV represents a shift in the vaginal microbiome from one that is dominated by Lactobac
Externí odkaz:
https://doaj.org/article/55a676e94a564afe9d3a9168c534e70e
Autor:
Yinan Zheng, Brian T. Joyce, Shih-Jen Hwang, Jiantao Ma, Lei Liu, Norrina B. Allen, Amy E. Krefman, Jun Wang, Tao Gao, Drew R. Nannini, Haixiang Zhang, David R. Jacobs, Myron D. Gross, Myriam Fornage, Cora E. Lewis, Pamela J. Schreiner, Stephen Sidney, Dongquan Chen, Philip Greenland, Daniel Levy, Lifang Hou, Donald M. Lloyd-Jones
Publikováno v:
Circulation. 146(2)
Background: Cardiovascular health (CVH) from young adulthood is strongly associated with an individual’s future risk of cardiovascular disease (CVD) and total mortality. Defining epigenomic biomarkers of lifelong CVH exposure and understanding thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddd50b5d7e775f2766f4443d1a8ee3d
https://pubmed.ncbi.nlm.nih.gov/35652342
https://pubmed.ncbi.nlm.nih.gov/35652342
Autor:
Drew R. Nannini, Yinan Zheng, Brian T. Joyce, Kyeezu Kim, Tao Gao, Jun Wang, David R. Jacobs, Pamela J. Schreiner, Kristine Yaffe, Philip Greenland, Donald M. Lloyd-Jones, Lifang Hou
Publikováno v:
Molecular Psychiatry.
Marijuana is a widely used psychoactive substance in the US and medical and recreational legalization has risen over the past decade. Despite the growing number of individuals using marijuana, studies investigating the association between epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64063d625bee3c7f90775bea4850617b
https://doi.org/10.1038/s41380-023-02106-y
https://doi.org/10.1038/s41380-023-02106-y