Zobrazeno 1 - 10
of 112
pro vyhledávání: '"R, Nani"'
Autor:
Roger R. Nani, Alexander P. Gorka, Tadanobu Nagaya, Tsuyoshi Yamamoto, Joseph Ivanic, Hisataka Kobayashi, Martin J. Schnermann
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 329-337 (2017)
Externí odkaz:
https://doaj.org/article/78afb6d3818d4c2f843d520e870b9349
Autor:
Hisataka Kobayashi, Martin J. Schnermann, Peter L. Choyke, Yasuhiro Maruoka, Fusa Ogata, Shuhei Okuyama, Roger R. Nani, Alexander P. Gorka, Tadanobu Nagaya
Absorbance spectra of both Ab-conjugates for additional QC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279883df7234ae707eaece83672b3154
https://doi.org/10.1158/1535-7163.22505509.v1
https://doi.org/10.1158/1535-7163.22505509.v1
Autor:
Hisataka Kobayashi, Martin J. Schnermann, Peter L. Choyke, Yasuhiro Maruoka, Fusa Ogata, Shuhei Okuyama, Roger R. Nani, Alexander P. Gorka, Tadanobu Nagaya
Near-infrared photoimmunotherapy (NIR-PIT) is a highly selective tumor treatment that uses an antibody–photoabsorber conjugate (APC). However, the effect of NIR-PIT can be enhanced when combined with other therapies. NIR photocaging groups, based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7421898af26dcdddffe1fa7bc611ecfb
https://doi.org/10.1158/1535-7163.c.6538096.v1
https://doi.org/10.1158/1535-7163.c.6538096.v1
Autor:
So-Hyun Nam, Choonghee Lee, Jung-Man Namgoong, Roger R. Nani, Il Hyung Shin, Martin J. Schnermann, Jaepyeong Cha, Michael Luciano
Publikováno v:
Mol Pharm
Despite advances, visual inspection, palpation, and intraoperative ultrasound remain the most utilized tools during surgery today. A particularly challenging issue is the identification of the biliary system due to its complex architecture partially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb87bb8275652949402608d2f6c3d5a
https://doi.org/10.1021/acs.molpharmaceut.9b00453
https://doi.org/10.1021/acs.molpharmaceut.9b00453
Autor:
Martin J. Schnermann, Michael Luciano, Simone Difilippantonio, Nimit L. Patel, Stephen N. Crooke, Roger R. Nani, Christina Robinson, Saghar Nourian, Joseph D. Kalen, Ivan P. Dingle, Gabriel Kline, M. G. Finn
Publikováno v:
ACS Chemical Biology. 14:934-940
[Image: see text] Heptamethine cyanines are broadly used for a range of near-infrared imaging applications. As with many fluorophores, these molecules are prone to forming nonemissive aggregates upon biomolecule conjugation. Prior work has focused on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0223724f8a3fb117fa4dddb34833f1ba
https://doi.org/10.1021/acschembio.9b00122
https://doi.org/10.1021/acschembio.9b00122
Autor:
Michael P, Luciano, Saghar, Nourian, Alexander P, Gorka, Roger R, Nani, Tadanobu, Nagaya, Hisataka, Kobayashi, Martin J, Schnermann
Publikováno v:
Methods in enzymology. 641
Optical methods offer the potential to manipulate living biological systems with exceptional spatial and temporal control. Caging bioactive molecules with photocleavable functional groups is an important strategy that could be applied to a range of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9b3266427ee82a3c7c7389d0eb35e7f
https://pubmed.ncbi.nlm.nih.gov/32713525
https://pubmed.ncbi.nlm.nih.gov/32713525
Autor:
Tadanobu Nagaya, Martin J. Schnermann, Alexander P. Gorka, Roger R. Nani, Hisataka Kobayashi, Michael Luciano, Saghar Nourian
Optical methods offer the potential to manipulate living biological systems with exceptional spatial and temporal control. Caging bioactive molecules with photocleavable functional groups is an important strategy that could be applied to a range of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba61fa1312051681a0879b7de700faf
https://doi.org/10.1016/bs.mie.2020.04.043
https://doi.org/10.1016/bs.mie.2020.04.043
Publikováno v:
Accounts of Chemical Research. 51:3226-3235
Optical approaches that visualize and manipulate biological processes have transformed modern biomedical research. An enduring challenge is to translate these powerful methods into increasingly complex physiological settings. Longer wavelengths, typi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a101fa79d9cd40318223e381b2516cc4
https://doi.org/10.1021/acs.accounts.8b00384
https://doi.org/10.1021/acs.accounts.8b00384
Autor:
Aline Broch, Gabriel Kline, Ki-Hoon Kim, Peter C.W. Kim, Martin J. Schnermann, Roger R. Nani, Jung-Man Namgoong, Rhushikesh A. Kulkarni, Jordan L. Meier, Jaepyeong Cha, Michael Luciano
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2741-2745
Surgical methods guided by exogenous fluorescent markers have the potential to define tissue types in real time. Small molecule dyes with efficient and selective renal clearance could enable visualization of the ureter during surgical procedures invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad79999caa4c3116e0d8cb23f847513e
https://doi.org/10.1016/j.bmcl.2018.02.040
https://doi.org/10.1016/j.bmcl.2018.02.040
Autor:
Tadanobu Nagaya, Joseph Ivanic, Martin J. Schnermann, Roger R. Nani, Tsuyoshi Yamamoto, Hisataka Kobayashi, Alexander P. Gorka
Publikováno v:
ACS Central Science
ACS Central Science, Vol 3, Iss 4, Pp 329-337 (2017)
ACS Central Science, Vol 3, Iss 4, Pp 329-337 (2017)
Near-IR photocaging groups based on the heptamethine cyanine scaffold present the opportunity to visualize and then treat diseased tissue with potent bioactive molecules. Here we describe fundamental chemical studies that enable biological validation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcec55a82df5764340138277023a1ee
https://doi.org/10.1021/acscentsci.7b00026
https://doi.org/10.1021/acscentsci.7b00026