Zobrazeno 1 - 10
of 239
pro vyhledávání: '"R, Nagle"'
Autor:
T. Todd Lindley, Gregory P. Murdoch, Jared L. Guyer, Gary D. Skwira, Kenneth J. Schneider Schneider, Seth R. Nagle, Kurt M. Van Speybroeck, Bradley R. Smith, Micah-John Beierle
Publikováno v:
E-Journal of Severe Storms Meteorology. 9:1-43
Destructive wildfire outbreaks are a preeminent natural hazard on the grass-dominated landscape of the southern Great Plains. These southern Great Plains wildfire outbreaks (SGPWOs) are characterized by tens of wildfires that evolve on spatial and te
Autor:
Jeffrey R. Kugelman, Johanny Kugelman-Tonos, Jason T. Ladner, James Pettit, Carolyn M. Keeton, Elyse R. Nagle, Karla Y. Garcia, Jeffrey W. Froude, Ana I. Kuehne, Jens H. Kuhn, Sina Bavari, Larry Zeitlin, John M. Dye, Gene G. Olinger, Mariano Sanchez-Lockhart, Gustavo F. Palacios
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 2111-2120 (2015)
MB-003, a plant-derived monoclonal antibody cocktail used effectively in treatment of Ebola virus infection in non-human primates, was unable to protect two of six animals when initiated 1 or 2 days post-infection. We characterized a mechanism of vir
Externí odkaz:
https://doaj.org/article/dc883dcf66c3464cadf39bdec67933ae
Autor:
Jeffrey R Kugelman, Michael R Wiley, Elyse R Nagle, Daniel Reyes, Brad P Pfeffer, Jens H Kuhn, Mariano Sanchez-Lockhart, Gustavo F Palacios
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171333 (2017)
Individual RNA viruses typically occur as populations of genomes that differ slightly from each other due to mutations introduced by the error-prone viral polymerase. Understanding the variability of RNA virus genome populations is critical for under
Externí odkaz:
https://doaj.org/article/8b42225205ea4feeaa01d8501c50fe52
Autor:
Jeffrey R Kugelman, Cynthia A Rossi, Michael R Wiley, Jason T Ladner, Elyse R Nagle, Bradley P Pfeffer, Karla Garcia, Karla Prieto, Jiro Wada, Jens H Kuhn, Gustavo Palacios
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150919 (2016)
The creation of licensed medical countermeasures against Select Agents such as Ebola virus (EBOV) is critically dependent on the use of standardized reagents, assays, and animal models. We performed full genome reconstruction, population genomics, co
Externí odkaz:
https://doaj.org/article/91d82b4b5f7f4c129b12f814c373d0de
Autor:
Lorena Lewis, Elyse R. Nagle, Camila P Olivera, Carla Bellomo, Josefina Campos, JA Diaz, Constanza Anselmo, Valeria P. Martinez, Fernanda Pontoriero, Bonnie Dighero-Kemp, Jens H. Kuhn, Enzo Lavarra, Daniel Cisterna, Miriam I Burgos, Peter A. Larson, Ayelén A Iglesias, Mario Kaler, Beatriz López, Rocío Coelho, Daniel Oscar Alonso, Adolfo Rubinstein, Emiliano Biondo, Natalia Periolo, Jeffrey R. Kugelman, Heema Sharma, Unai Pérez-Sautu, Gustavo Palacios, Teresa Strella, Mariano Sanchez-Lockhart, Claudia Perandones, Alexis Edelstein, Catherine B. Pratt, Nicholas Di Paola, Joseph A. Chitty
Publikováno v:
New England Journal of Medicine
From November 2018 through February 2019, person-to-person transmission of Andes virus (ANDV) hantavirus pulmonary syndrome occurred in Chubut Province, Argentina, and resulted in 34 confirmed infections and 11 deaths. Understanding the genomic, epid
Autor:
Catherine E. Arnold, Jonathan C. Guito, Louis A. Altamura, Sean P. Lovett, Elyse R. Nagle, Gustavo F. Palacios, Mariano Sanchez-Lockhart, Jonathan S. Towner
Publikováno v:
Viruses, Vol 10, Iss 11, p 607 (2018)
The Egyptian rousette bat (ERB) is the only known Marburg virus (MARV) reservoir host. ERBs develop a productive MARV infection with low viremia and shedding but no overt disease, suggesting this virus is efficiently controlled by ERB antiviral respo
Externí odkaz:
https://doaj.org/article/7e83f0c56047489788b32a23531b7fd4
Autor:
Joseph N. Fair, Maria Makuwa, Jens H. Kuhn, Gustavo Palacios, Jean-Jacques Muyembe-Tamfum, Jeffrey R. Kugelman, Prime Mulembakani, Raina Kumar, Joshua Richardson, Nicholas Di Paola, Elyse R. Nagle, Randal J. Schoepp, Nadia Wauquier, Jarod Hanson, Christine E. Hulseberg, Mariano Sanchez-Lockhart, Peter A. Larson
Publikováno v:
Cell Reports Medicine
Summary Bundibugyo virus (BDBV) is one of four ebolaviruses known to cause disease in humans. Bundibugyo virus disease (BVD) outbreaks occurred in 2007–2008 in Bundibugyo District, Uganda, and in 2012 in Isiro, Province Orientale, Democratic Republ
Autor:
Elyse R. Nagle, John H. Connor, Arthur J. Goff, Louis A. Altamura, Korey L. Delp, Randal J. Schoepp, William Aguilar, Sandra L. Bixler, Timothy D. Minogue, Kirsten Kulcsar, Christina E. Douglas, Gustavo Palacios, Cynthia A. Rossi, Emily Speranza
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Ebola virus disease (EVD) is a serious illness with mortality rates of 20–90% in various outbreaks. EVD is characterized by robust virus replication and strong host inflammatory response. Analyzing host immune responses has increasingly involved mu
Autor:
Travis K. Warren, Elyse R. Nagle, Nicole Espy, Michael R. Wiley, Alex J. Chitty, Brad P. Pfeffer, Mariano Sanchez-Lockhart, Gustavo Palacios, Sina Bavari, Karla Garcia
Publikováno v:
Antiviral research. 170
Nucleoside analogues (NA) disrupt RNA viral RNA-dependent RNA polymerase (RdRP) function and fidelity for multiple viral families. The mechanism of action (MOA) of T-705 has been attributed alternatively or concurrently to chain termination and letha
Autor:
Xungai Wang, Alexander R Nagle, Cormac Fay, Michael J. Higgins, Gordon G. Wallace, Zhigang Xie
Publikováno v:
Nanotechnology. 30(19)
Near-field electrospinning (NFES) is widely recognized as a versatile nanofabrication method, one suitable for applications in tissue engineering. Rapid developments in this field have given rise to layered nanofibrous scaffolds. However, this electr