Zobrazeno 1 - 10
of 108
pro vyhledávání: '"R, Monteleone"'
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: To investigate the pharmacokinetics, pharmacodynamics, and exposure–response of the approved 900/1,200 mg dosing regimen for the terminal complement component 5 (C5) inhibitor eculizumab in patients with generalized myasthenia gravis (gM
Externí odkaz:
https://doaj.org/article/a4769ce0c1ae43f096e7ccb380048d98
Publikováno v:
Infectious Diseases and Therapy
Introduction Terminal complement amplification is hypothesized to be a key contributor to the clinical manifestations of severe coronavirus disease 2019 (COVID-19). Ravulizumab, a humanized monoclonal antibody that binds with high affinity to complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8668b90c3514d966cd6d9cc3bdd10d38
https://doi.org/10.1007/s40121-021-00425-7
https://doi.org/10.1007/s40121-021-00425-7
Autor:
Richard M. Burwick, Gabriela Dellapiana, Rachel A. Newman, Sarah D. Smithson, Mariam Naqvi, John Williams, Melissa S. Wong, Martha Bautista, Anna Gaden, Shamsah D. Kazani, Derek A. Dunn, Mark H. Ma, Sanjay Mitter, Jonathan P. R. Monteleone, Stephan R. Ortiz, Sara Ghandehari, Noah Merin, Mark I. Zakowski, S. Ananth Karumanchi
Publikováno v:
American Journal of Reproductive Immunology. 88
We evaluated eculizumab, a complement protein C5 inhibitor, for treatment of severe COVID-19 in pregnant and postpartum individuals.Protocol ECU-COV-401 (clinicaltrials.gov NCT04355494) is an open label, multicenter, Expanded Access Program (EAP), ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c31a59128dace279973867dbb352e46
https://doi.org/10.1111/aji.13559
https://doi.org/10.1111/aji.13559
Akademický článek
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Autor:
Dong hee Chung, Jie Li, Michael D. Toney, Yao Chiang, Yuru Wang, Leanna R. Monteleone, Peter A. Beal
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 47, iss 20
Nucleic acids research, vol 47, iss 20
Human ADAR3 is a catalytically inactive member of the Adenosine Deaminase Acting on RNA (ADAR) protein family, whose active members catalyze A-to-I RNA editing in metazoans. Until now, the reasons for the catalytic incapability of ADAR3 has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c01f40d3bbc6952ff6c5c014eb57d3
https://doi.org/10.1093/nar/gkz815
https://doi.org/10.1093/nar/gkz815
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology, Vol 12 (2021)
Objective: To investigate the pharmacokinetics, pharmacodynamics, and exposure–response of the approved 900/1,200 mg dosing regimen for the terminal complement component 5 (C5) inhibitor eculizumab in patients with generalized myasthenia gravis (gM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2456b60cc0f2dc2d56a137ca7b9eea
https://pubmed.ncbi.nlm.nih.gov/34795626
https://pubmed.ncbi.nlm.nih.gov/34795626
Autor:
Megan M. Korn, Colin Swenson, Ryan P. Johnson, Deanna M. Dailey, Steve D. Knutson, Peter A. Beal, Leanna R. Monteleone, Jennifer M. Heemstra
Publikováno v:
Chemistry
Chemistry (Weinheim an der Bergstrasse, Germany), vol 26, iss 44
Chemistry (Weinheim an der Bergstrasse, Germany), vol 26, iss 44
Straightforward methods for detecting adenosine-to-inosine (A-to-I) RNA editing are key to a better understanding of its regulation, function, and connection with disease. We address this need by developing a novel reagent, N-(4-ethynylphenyl)acrylam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38af36310b7c8ca5f49a288596d4fdad
https://europepmc.org/articles/PMC7674219/
https://europepmc.org/articles/PMC7674219/
Autor:
M.C. Cava, G. Cappiello, G. Manetti, R. Monteleone, M. Visca, L. Balducci, F. Dastoli, A. Spanò
Publikováno v:
Microbiologia Medica, Vol 21, Iss 3 (2006)
Externí odkaz:
https://doaj.org/article/544f5ea4c07d486198b167629b7147ee
Publikováno v:
Microbiologia Medica, Vol 21, Iss 3 (2006)
Externí odkaz:
https://doaj.org/article/6b6fdc5a3c054356b473e0a8a6eb51d8
The effect of pendant group structure on the thermoresponsive properties of N-substituted polyesters
Autor:
Michael R. Martinez, Abraham Joy, Megan A. Cruz, John P. Swanson, Leanna R. Monteleone, Philip J. Costanzo
Publikováno v:
Polymer Chemistry. 8:7195-7206
Synthetic polymers exhibiting reversible lower critical solution temperature (LCST), such as poly(N-isopropylacrylamide) (PNIPAM), are intriguing materials with various potential applications. We recently developed a new class of biodegradable thermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::019da81e009e6f17cc430f83ac4f99d6
https://doi.org/10.1039/c7py01391d
https://doi.org/10.1039/c7py01391d