Zobrazeno 1 - 10
of 907
pro vyhledávání: '"R, Mendelsohn"'
Autor:
Andrew R, Mendelsohn, James W, Larrick
Publikováno v:
Rejuvenation Research. 25:39-45
The development of senomorphic drugs to attenuate the senescent phenotype and senolytics to clear pro-inflammatory senescent cells (SCs) to treat aging-associated disorders is being hotly pursued. The effort is complicated by the fact that SCs play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f977e376b0b19e5c22bb4563a5dd1b28
https://doi.org/10.1089/rej.2022.0008
https://doi.org/10.1089/rej.2022.0008
Autor:
Andrew R Mendelsohn, James W Larrick
Publikováno v:
Rejuvenation Research. 24:470-474
Stem cell dysfunction is a hallmark of aging. Much recent study suggests that epigenetic changes play a critical role in the loss of stem cell function with age. However, the underlying mechanisms require elucidation. A recent report describes a proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f261ee3cc215345e6d96e24422f0f4f
https://doi.org/10.1089/rej.2021.0076
https://doi.org/10.1089/rej.2021.0076
Autor:
K.I. Agladze, Ibrahim Akin, Michail A. Alterman, Abdolreza Ardeshirylajimi, Alessia Bertero, Rahulkumar Bhoi, Natacha Breuls, Anne Bush, Francesca Caloni, Ivan Carcamo-Orive, Zhifen Chen, Teresa Coccini, Massimo Conese, Chad A. Cowan, Nathan James Cunningham, Ibrahim El-Battrawy, Benjamin S. Freedman, Andrée Gauthier-Fisher, Melkamu Getie-Kebtie, Nefele Giarratana, Madelyn A. Gillentine, Christopher Grunseich, Mirabelle S.H. Ho, Miriel S.H. Ho, Deborah A. Hursh, Gentaro Ikeda, Ji Hye Jung, Martin H. Kang, Yong Kyun Kim, Jacqueline Kowitz, Siegfried Lang, Onofrio Laselva, Jennifer Lei, Sandra L. Leibel, Clifford L. Librach, Geoffrey P. Lomax, Maryam Mahmoodinia Maymand, Rachael N. McVicar, Andrew R. Mendelsohn, Anna R. Mendelsohn, Sadegh lotfalah Moradi, Yasuhiro Murakawa, Dan Nir, Connor G. O'Brien, A.D. Podgurskaya, Natalia S. Pripuzova, Maurilio Sampaolesi, M.M. Slotvitsky, Evan Y. Snyder, Shi Su, Colin Sweeney, Bernard Thébaud, V.A. Tsvelaya, Haritha Vallabhaneni, Evgeniya A. Vaskova, Huaxiao Yang, Phillip C. Yang, Laura Yedigaryan, Masahito Yoshihara, Xiaobo Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d308ba69a79386fc00d6f4eab904758
https://doi.org/10.1016/b978-0-323-99892-5.01002-1
https://doi.org/10.1016/b978-0-323-99892-5.01002-1
Publikováno v:
Rejuvenation Research. 24:319-324
Inflammaging, the increase of proinflammatory processes with increasing age, has multiple mechanisms from increasing numbers of senescent cells secreting cytokines to changes in metabolic processes. Alterations of oxygen metabolism with aging, especi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9643892106c718a5168968abad3f2ef
https://doi.org/10.1089/rej.2021.0051
https://doi.org/10.1089/rej.2021.0051
Publikováno v:
Rejuvenation Research. 24:234-237
Intermittent fasting (IF) is the practice of restricting food intake for 12-48 hours per fasting cycle over a prolonged period of time. Previous study shows beneficial health effects such as weight loss and lower risk for cardiometabolic diseases. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802b27390a75cb9ec9353b6c583989a5
https://doi.org/10.1089/rej.2021.0025
https://doi.org/10.1089/rej.2021.0025
Autor:
James W Larrick, Andrew R Mendelsohn
Publikováno v:
Rejuvenation Research. 23:171-175
Diminished integrity of the intestinal epithelial barrier with advanced age is believed to contribute to aging-associated dysfunction and pathologies in animals. In mammals, diminished gut integrity contributes to inflammaging, the increase in inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b32f9b784088ac6919c4eafb7a5722d
https://doi.org/10.1089/rej.2020.2335
https://doi.org/10.1089/rej.2020.2335
Autor:
Andrew R Mendelsohn, James W Larrick
Publikováno v:
Rejuvenation Research. 23:68-72
Although alterations in the sympathetic nervous system (SNS) with age have been reported, and serious degenerative diseases of the autonomic nervous system such as multiple system atrophy are more likely to strike older people, connections between dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10199fe476f9a03b6ab4940e33152fd1
https://doi.org/10.1089/rej.2020.2309
https://doi.org/10.1089/rej.2020.2309
Tidal gates have been in operation for centuries to block salt water from penetrating landscapes, while storm gates are relatively new. Storm gates block just severe storm surges while normally remaining open to allow salt water to move freely back a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ac879afc9e540ea8f74c063d40612f
Autor:
James W Larrick, Andrew R Mendelsohn
Publikováno v:
Rejuvenation research. 24(5)
Numerous studies demonstrate a global decrease in nicotinamide adenine dinucleotide (NAD+) with aging. This decline is associated with the development of several of the hallmarks of aging such as reduced mitophagy and neuroinflammation, processes tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227bedfb868ed0b371f0cf70a84bf189
https://pubmed.ncbi.nlm.nih.gov/34694148
https://pubmed.ncbi.nlm.nih.gov/34694148