Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project

Autor: C. Gilbault, G. Pelicci, Marian Beekman, Axel Skytthe, Serena Dato, A. Skouteri, Konstantinos Voutetakis, Luca Deiana, Ciriaco Carru, Ewa Sikora, Claudio Franceschi, Friederike Flachsbart, Leena Peltonen, James W. Vaupel, P. Laiho, Joanna Collerton, V. Bezrukov, Stefan Schreiber, Michel Poulain, Karen Davies, Irene Maeve Rea, Mikko Hurme, Giuseppe Passarino, Federica Sevini, Katarzyna Broczek, Outi Törnwall, Antti Hervonen, Elisa Cevenini, Hélène Blanché, Bernard Jeune, Maria Scurti, Rodolfo Cotichini, Jean-Marie Robine, Erica Haimes, A.J.M. de Craen, Thomas B. L. Kirkwood, R. Masciulli, José Remacle, Lene Christiansen, Dorota Janiszewska, F. Balard, Almut Nebel, A. Leon, P.E. Slagboom, Lars Bolund, A. Marchisio, Liana Spazzafumo, Marja Jylhä, Virgilia Toccaceli, G. De Benedictis, Markus Perola, Olivier Toussaint, Jutta Gampe, M A Stazi, Silvana Valensin, Peter Kristensen, Kaare Christensen, Efstathios S. Gonos

Publikováno v: Experimental Gerontology
Experimental Gerontology, 2011, 46 (11), pp.934-945. ⟨10.1016/j.exger.2011.08.005⟩
Experimental Gerontology, 46(11), 934-945
Skytthe, A, Valensin, S, Jeune, B, Cevenini, E, Balard, F, Beekman, M, Bezrukov, V, Blanche, H, Bolund, L, Broczek, K, Carru, C, Christensen, K, Christiansen, L, Collerton, J C, Cotichini, R, de Craen, A J M, Dato, S, Davies, K, De Benedictis, G, Deiana, L, Flachsbart, F, Gampe, J, Gilbault, C, Gonos, E S, Haimes, E, Hervonen, A, Hurme, M A, Janiszewska, D, Jylhä, M, Kirkwood, T B L, Kristensen, P, Laiho, P, Leon, A, Marchisio, A, Masciulli, R, Nebel, A, Passarino, G, Pelicci, G, Peltonen, L, Perola, M, Poulain, M, Rea, I M, Remacle, J, Robine, J M, Schreiber, S, Scurti, M, Sevini, F, Sikora, E, Skouteri, A, Slagboom, P E & for the GEHA consortium 2011, ' Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project ', Experimental Gerontology, vol. 46, no. 11, pp. 934-945 . https://doi.org/10.1016/j.exger.2011.08.005
Skytthe, A, Valensin, S, Jeune, B, Cevenini, E, Balard, F, Beekman, M, Bezrukov, V, Blanche, H, Bolund, L, Broczek, K, Carru, C, Christensen, K, Christiansen, L, Collerton, J C, Cotichini, R, de Craen, A J M, Dato, S, Davies, K, De Benedictis, G, Deiana, L, Flachsbart, F, Gampe, J, Gilbault, C, Gonos, E S, Haimes, E, Hervonen, A, Hurme, M A, Janiszewska, D, Jylhä, M, Kirkwood, T B L, Kristensen, P, Laiho, P, Leon, A, Marchisio, A, Masciulli, R, Nebel, A, Passarino, G, Pelicci, G, Peltonen, L, Perola, M, Poulain, M, Rea, I M, Remacle, J, Robine, J M, Schreiber, S, Scurti, M, Sevini, F, Sikora, E, Skouteri, A, Vaupel, J W & for the GEHA consortium 2011, ' Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project ', Experimental Gerontology, vol. 46, no. 11, pp. 934-45 . https://doi.org/10.1016/j.exger.2011.08.005
Experimental Gerontology, Elsevier, 2011, 46 (11), pp.934-945. ⟨10.1016/j.exger.2011.08.005⟩

In 2004, the integrated European project GEHA (Genetics of Healthy Ageing) was initiated with the aim of identifying genes involved in healthy ageing and longevity. The first step in the project was the recruitment of more than 2500 pairs of siblings

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ef9b377ae46928b4cda3635511f7e2
https://hal.science/hal-02937385/document

Sub-Nyquist field trial using time frequency packed DP-QPSK super-channel within fixed ITU-T grid

Autor: Luca Giorgi, Fabio Cavaliere, S. Hackett, Francesco Fresi, Marco Secondini, Gianluca Berrettini, A. Petronio, R. Forgan, A. Leong, C. Pfander, Gianluca Meloni, Tommaso Foggi, Luca Poti, P. Nibbs, R. Masciulli

Publikováno v: Optics Express. 23:16196

Sub-Nyquist time frequency packing technique was demonstrated for the first time in a super-channel field trial transmission over long-haul distances. The technique allows a limited spectral occupancy even with low order modulation formats. The trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbb8d6c143c60950f9b21d7223ecbc1
https://doi.org/10.1364/oe.23.016196

Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells

Autor: F, Grignani, U, Testa, M, Fagioli, T, Barberi, R, Masciulli, G, Mariani, C, Peschle, P G, Pelicci

Publikováno v: Cancer research. 55(2)

Acute promyelocytic leukemia (APL) is characterized by a t(15;17) chromosomal translocation with breakpoints within the retinoic acid alpha receptor (RAR alpha) gene on 17 and the PML gene, which encodes a putative transcription factor, on 15. A PML-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c66099dbff0c67591fbee19c2a5ace3
https://pubmed.ncbi.nlm.nih.gov/7529139

Adoptive immunotherapy of human cancer: the cytokine cascade and monocyte activation following high-dose interleukin 2 bolus treatment

Autor: G, Boccoli, R, Masciulli, E M, Ruggeri, P, Carlini, G, Giannella, E, Montesoro, G, Mastroberardino, G, Isacchi, U, Testa, F, Calabresi

Publikováno v: Cancer research. 50(18)

Serum concentration kinetics of gamma-interferon (IFN-gamma), neopterin, 2'-5' A synthetase and tumor necrosis factor alpha were determined in five cancer patients undergoing adoptive immunotherapy with high-dose interleukin 2 (IL-2) bolus infusion a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5862b5ce37bc534d405536240eebba9
https://pubmed.ncbi.nlm.nih.gov/2118421

Interleukin 2 in cancer therapy

Autor: U, Testa, E, Montesoro, D, Bulgarini, P, Samoggia, R, Masciulli, D, Habetswallner, A, Carè, G, Mariani, G, Giannella, G, Boccoli

Publikováno v: Annali dell'Istituto superiore di sanita. 26(3-4)

The goal of adoptive immunotherapy is the stimulation of host antitumor immunity, either cellular or humoral. The introduction of recombinant human cytokines into clinical oncology represents a new useful tool for the development of new strategies of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a67a91d14c03538d03f8d516b20d3e5d
https://pubmed.ncbi.nlm.nih.gov/2091501