Zobrazeno 1 - 10
of 1 028
pro vyhledávání: '"R, Maclean"'
Autor:
Alla Ivanchikova, Robert R. Maclean
Situated in a particular historical moment marked by the violent crises of capitalism—the rise of the alt-right, the COVID-19 pandemic, and the Black Lives Matter movement—The Future of Lenin collects essays by an international cohort of scholars
Autor:
Pramod K Jangir, Lois Ogunlana, Petra Szili, Marton Czikkely, Liam P Shaw, Emily J Stevens, Yang Yu, Qiue Yang, Yang Wang, Csaba Pál, Timothy R Walsh, Craig R MacLean
Publikováno v:
eLife, Vol 12 (2023)
Antimicrobial peptides (AMPs) offer a promising solution to the antibiotic resistance crisis. However, an unresolved serious concern is that the evolution of resistance to therapeutic AMPs may generate cross-resistance to host AMPs, compromising a co
Externí odkaz:
https://doaj.org/article/5226b086e49e4490b45db13401c5d207
Autor:
Margaret R. MacLean, Divya Pandya, Emilia M. Swietlik, Nina Denver, Kirsty Mair, Nicholas W. Morrell, Stefan Gräf, National Cohort Study for Idiopathic and Heritable Pulmonary Arterial Hypertension Consortium
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract The hypothesis that a relationship exists between body mass index (BMI), functional class, and 6 min walk distance (6MWD) in Group 1‐pulmonary arterial hypertension (PAH) was examined. Analysis of data from the UK National Cohort Study for
Externí odkaz:
https://doaj.org/article/dec4cb90876246eabc4530ead367a981
Autor:
Craig K. Docherty, Nina Denver, Simon Fisher, Margaret Nilsen, Dianne Hillyard, Rebecca L. Openshaw, Hicham Labazi, Margaret R. MacLean
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 396-405 (2020)
The 5HT1B receptor (5HT1BR) contributes to the pathogenic effects of serotonin in pulmonary arterial hypertension. Here, we determine the effect of a microRNA96 (miR96) mimic delivered directly to the lungs on development of severe pulmonary hyperten
Externí odkaz:
https://doaj.org/article/e5d263e8dc1b4639b7c47108893f55bc
Autor:
Ameer Farooq, Alysha R. Keehn, Yuan Xu, Shiying Kong, Winson Y. Cheung, May Lynn Quan, Anthony R. MacLean
Publikováno v:
Canadian Journal of Surgery. 66:E71-E78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6ff30e8815228d89c6a480c5c460399
https://doi.org/10.1503/cjs.024320
https://doi.org/10.1503/cjs.024320
Obesity, estrogens and adipose tissue dysfunction – implications for pulmonary arterial hypertension
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Obesity is a prevalent global public health issue characterized by excess body fat. Adipose tissue is now recognized as an important endocrine organ releasing an abundance of bioactive adipokines including, but not limited to, leptin, adiponectin and
Externí odkaz:
https://doaj.org/article/e707a74b117e4b268d08481bf3564675
Autor:
Kathryn S. Wilson, Hanna Buist, Kornelija Suveizdyte, John T. Liles, Grant R. Budas, Colin Hughes, Margaret R. MacLean, Martin Johnson, Alistair C. Church, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinas
Externí odkaz:
https://doaj.org/article/6525394d6a864924aa813898fecdb00f
Autor:
Nina Denver, Natalie Z.M. Homer, Ruth Andrew, Katie Y. Harvey, Nicholas Morrell, Eric D. Austin, Margaret R. MacLean
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Increased risk and severity of idiopathic pulmonary arterial hypertension (iPAH) is associated with elevated estradiol in men and postmenopausal women. Pulmonary arteries synthesise estradiol via aromatase and metabolise it via CYP1B1 to mitogenic me
Externí odkaz:
https://doaj.org/article/59a9d1e549ce4bb4a4d9563178b30633
Autor:
Geeshath Jayasekera, Kathryn S. Wilson, Hanna Buist, Rosemary Woodward, Aysel Uckan, Colin Hughes, Margaret Nilsen, A Colin Church, Martin K. Johnson, Lindsay Gallagher, James Mullin, Mandy R. MacLean, William M. Holmes, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological feature
Externí odkaz:
https://doaj.org/article/16df05497cb345c3b63ec397451bbf19
Autor:
Nina Denver, Shazia Khan, Ioannis Stasinopoulos, Colin Church, Natalie Z.M. Homer, Margaret R. MacLean, Ruth Andrew
Publikováno v:
Data in Brief, Vol 23, Iss , Pp - (2019)
Analysis of catechol estrogens (2 & 4 hydroxy-estrone and estradiol) has proven troublesome by liquid chromatography tandem mass spectrometry due to their low concentrations, short half-lives and temperature-labile nature. Derivatization to methyl pi
Externí odkaz:
https://doaj.org/article/2d75ca2bfc4040fd898baa7771185ed1