Zobrazeno 1 - 10
of 223
pro vyhledávání: '"R, Lindmar"'
Low renin hypertension probably does not represent a clinical entity. In many patients with low renin hypertension blood pressure is normalized by treatment with diuretics only; in these patients a (genetic?) sensitivity to salt might play a predomin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8bf709d19fc66c978b03fc40b646b8
https://doi.org/10.1159/000400616
https://doi.org/10.1159/000400616
Autor:
R. Lindmar, Konrad Löffelholz
Publikováno v:
European Journal of Pharmacology. 190:251-254
Tacrine, 10(-6) M, enhanced the acetylcholine (ACh) overflow evoked in perfused chicken hearts by field stimulation (5 Hz, 1 min) from 183 to 346 pmol g-1 min-1. Increase to the same level were observed after pretreatment with diisopropylfluorophosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf74739b3d8badec825c73c989d9aa
https://doi.org/10.1016/0014-2999(90)94134-j
https://doi.org/10.1016/0014-2999(90)94134-j
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 188:89-95
The efflux of choline was determined in rat striatal slices, incubated chicken atria and perfused chicken hearts. 4 beta-Phorbol-12 beta,13 alpha-dibutyrate (PDB) and 4 beta-phorbol-12 beta-myristate, 13 alpha-acetate (PMA) were used to stimulate pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c9ec30b6b07fae1acfaf9b6f72be91
https://doi.org/10.1016/0922-4106(90)90043-w
https://doi.org/10.1016/0922-4106(90)90043-w
Autor:
R. Lindmar, Konrad Löffelholz
Publikováno v:
Biochemical pharmacology. 56(7)
Activation of phospholipase D (PLD) and phosphoinositide-specific phospholipase C (PI-PLC) by fluoride, to stimulate heterotrimeric G-proteins, and by phorbol esters, to stimulate protein kinase C (PKC), was studied in rat atria. Fluoride and 4beta-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8145f30d1d41542683eeee5f479e6756
https://pubmed.ncbi.nlm.nih.gov/9774141
https://pubmed.ncbi.nlm.nih.gov/9774141
Publikováno v:
Progress in brain research. 109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b98e9e8e4ad2688852a01b6fd0ca31d
https://pubmed.ncbi.nlm.nih.gov/9009708
https://pubmed.ncbi.nlm.nih.gov/9009708
Autor:
Konrad Löffelholz, R. Lindmar
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 346
Evidence for a general role of phospholipase D in signal transduction is accumulating. In the present study, the activity of the enzyme was investigated in heart tissue under basal conditions and after addition of phorbol esters or aluminum fluoride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea94d85e00729f47fd8038f9b92717af
https://doi.org/10.1007/bf00168732
https://doi.org/10.1007/bf00168732
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 346(4)
The effects of muscarinic receptor antagonists on ACh release were studied in the absence or presence of cholinesterase (ChE) inhibition using the isolated perfused chicken heart. Presynaptic inhibitory muscarinic autoreceptor were characterized by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6819914feae8b04986492a39e34aa7
https://pubmed.ncbi.nlm.nih.gov/1436122
https://pubmed.ncbi.nlm.nih.gov/1436122
Publikováno v:
Biological Signal Transduction ISBN: 9783642751387
Phospholipase D (PLD) hydrolyzes phosphatidylcholine and thereby seems to play a key role in a novel pathway of signal transduction. PLD activity in rat hippocampal slices and atria of rat, guinea pig and chicken hearts was determined by measuring th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918502daa0926d2c61dee5282e477066
https://doi.org/10.1007/978-3-642-75136-3_31
https://doi.org/10.1007/978-3-642-75136-3_31
Publikováno v:
British Journal of Pharmacology. 93:357-366
1. Electrically driven chicken and guinea-pig atria were used to investigate the negative inotropic effects of the muscarinic agonists methacholine and acetylcholine (ACh). The release of ACh from isolated hearts into the perfusate in response to (pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3717d8af6c81040805a8c472a5fccb
https://doi.org/10.1111/j.1476-5381.1988.tb11442.x
https://doi.org/10.1111/j.1476-5381.1988.tb11442.x
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 318:295-300
The efflux of acetylcholine, of radioactively labelled acetylcholine and choline, into the venous effluent of the perfused chicken heart was studied to determine the kinetics of both interstitial washout and hydrolysis of acetylcholine. Stimulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f526c4ed4f6a522e7cb629e88864f2ee
https://doi.org/10.1007/bf00501168
https://doi.org/10.1007/bf00501168