Zobrazeno 1 - 10
of 581
pro vyhledávání: '"R, Lawler"'
Autor:
Jacob C. Jentzer, Yogesh N.V. Reddy, Sabri Soussi, Ruben Crespo‐Diaz, Parag C. Patel, Patrick R. Lawler, Alexandre Mebazaa, Shannon M. Dunlay
Publikováno v:
ESC Heart Failure, Vol 11, Iss 6, Pp 4242-4256 (2024)
Abstract Aims Hospitalized patients with heart failure (HF) are a heterogeneous population, with multiple phenotypes proposed. Prior studies have not examined the biological phenotypes of critically ill patients with HF admitted to the contemporary c
Externí odkaz:
https://doaj.org/article/1b9e090feb37462b83ab56d1a4cf54a0
Publikováno v:
JACC: Advances, Vol 3, Iss 9, Pp 101197- (2024)
Externí odkaz:
https://doaj.org/article/f5b4d73ff10e4f82b0d4f5589dd7fa59
Autor:
Sabri Soussi, Mojtaba Ahmadiankalati, Jacob C. Jentzer, John C. Marshall, Patrick R. Lawler, Margaret Herridge, Alexandre Mebazaa, Etienne Gayat, Zihang Lu, Claudia C. dosSantos, the French and European Outcome Registry in Intensive Care Units (FROG‐ICU) and CCCTBG trans‐trial group study for InFACT – the International Forum for Acute Care Trialists
Publikováno v:
ESC Heart Failure, Vol 11, Iss 2, Pp 1242-1248 (2024)
Abstract Aims An elevated risk of adverse events persists for years in cardiogenic shock (CS) survivors with high mortality rate and physical/mental disability. This study aims to link clinical CS‐survivor phenotypes with distinct late host‐respo
Externí odkaz:
https://doaj.org/article/9390ce306a4e402c9caf63537f567cc7
Autor:
Sylvain A. Lother, Lana Tennenhouse, Rasheda Rabbani, Ahmed M. Abou-Setta, Nicole Askin, Alexis F. Turgeon, Srinivas Murthy, Brett L. Houston, Donald S. Houston, Asher A. Mendelson, Jonathan D. Paul, Michael E. Farkouh, Jovan Hasmatali, Barret Rush, Joel Nkosi, Ewan C. Goligher, Emily Rimmer, John C. Marshall, Souradet Y. Shaw, Patrick R. Lawler, Yoav Keynan, Ryan Zarychanski
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 5, Pp 102526- (2024)
Background: Community-acquired pneumonia (CAP) triggers inflammatory and thrombotic host responses driving morbidity and mortality. Antiplatelet agents may favorably modulate these pathways; however, their role in non–COVID-19 CAP remains uncertain
Externí odkaz:
https://doaj.org/article/57373b1e9cdf4488a5be3c22ae4d42e4
Autor:
Federico Angriman, MD, MPH, PhD, Jutamas Saoraya, MD, PhD, Patrick R. Lawler, MD, MPH, Baiju R. Shah, MD, PhD, Claudio M. Martin, MD, MSc, Damon C. Scales, MD, PhD, on behalf of the Sepsis Canada Network
Publikováno v:
Critical Care Explorations, Vol 6, Iss 5, p e1085 (2024)
OBJECTIVES:. We assessed the association of preexisting diabetes mellitus with all-cause mortality and organ support receipt in adult patients with sepsis. DESIGN:. Population-based cohort study. SETTING:. Ontario, Canada (2008–2019). POPULATION:.
Externí odkaz:
https://doaj.org/article/e4a5c8c11c2549b0a98aa9b0f641ebd1
Autor:
Sabri Soussi, Claudia dos Santos, Jacob C. Jentzer, Alexandre Mebazaa, Etienne Gayat, Janine Pöss, Hannah Schaubroeck, Filio Billia, John C. Marshall, Patrick R. Lawler
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Circulatory shock is defined syndromically as hypotension associated with tissue hypoperfusion and often subcategorized according to hemodynamic profile (e.g., distributive, cardiogenic, hypovolemic) and etiology (e.g., infection, myocardial
Externí odkaz:
https://doaj.org/article/0fc7c390b1824d438226e300f9975299
Autor:
Federico Angriman, Patrick R. Lawler, Baiju R. Shah, Claudio M. Martin, Damon C. Scales, the Sepsis Canada Network
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-10 (2023)
Abstract Background Sepsis survivors are at elevated risk for cardiovascular disease during long-term follow-up. Whether diabetes influences cardiovascular risk after sepsis survival remains unknown. We sought to describe the association of diabetes
Externí odkaz:
https://doaj.org/article/734152ade46f4116bc2dec6fc2397497
Autor:
Patrick R. Lawler, MD, MPH, Garen Manvelian, PhD, Alida Coppi, PhD, Amy Damask, PhD, Michael N. Cantor, MD, Manuel A. R. Ferreira, PhD, Charles Paulding, PhD, Nilanjana Banerjee, PhD, Dadong Li, PhD, Susan Jorgensen, MS, Richa Attre, PhD, David J. Carey, PhD, Kristi Krebs, PhD, Lili Milani, PhD, Kristian Hveem, MD, Jan K. Damås, PhD, Erik Solligård, PhD, Stefan Stender, MD, Anne Tybjærg-Hansen, MD, Børge G. Nordestgaard, MD, Tamara Hernandez-Beeftink, PhD, Tormod Rogne, MD, Carlos Flores, PhD, Jesús Villar, MD, Keith R. Walley, MD, Vincent X. Liu, MD, Alison E. Fohner, PhD, Luca A. Lotta, MD, Christos A. Kyratsous, PhD, Mark W. Sleeman, PhD, Michel Scemama, MD, Richard DelGizzi, MS, Robert Pordy, MD, Julie E. Horowitz, PhD, Aris Baras, MD, Greg S. Martin, MD, Philippe Gabriel Steg, MD, Gregory G. Schwartz, MD, Michael Szarek, PhD, Shaun G. Goodman, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0997 (2023)
OBJECTIVES:. Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early inhibition of proprotein conve
Externí odkaz:
https://doaj.org/article/9668af2bf04b4033991c97345adef80d
Autor:
Subodh Verma, Andrew Kosmopoulos, Deepak L. Bhatt, David Fitchett, Anne Pernille Ofstad, Christoph Wanner, Michaela Mattheus, Bernard Zinman, Patrick R. Lawler, Lawrence A. Leiter
Publikováno v:
American Journal of Preventive Cardiology, Vol 15, Iss , Pp 100510- (2023)
Objectives: REDUCE-IT showed that icosapent ethyl (IPE) improved cardiovascular (CV) outcomes in participants with established CV disease (CVD) or type 2 diabetes (T2D) and at least one additional risk factor plus mild-moderate hypertriglyceridemia a
Externí odkaz:
https://doaj.org/article/d083c1a8463845e48238f05fb086aa8d
Autor:
Leo E. Akioyamen, MD, Anna Chu, MHSc, Jacques Genest, MD, Douglas S. Lee, MD, PhD, Husam Abdel-Qadir, MD, PhD, Cynthia A. Jackevicius, BScPhm, PharmD, MSc, Patrick R. Lawler, MD, MPH, Maneesh Sud, MD, Jacob A. Udell, MD, MPH, Harindra C. Wijeysundera, MD, PhD, Dennis T. Ko, MD, MSc
Publikováno v:
CJC Open, Vol 4, Iss 9, Pp 739-747 (2022)
Background: A simplified Canadian definition was recently developed to enable identification of individuals with familial hypercholesterolemia (FH) and severe hypercholesterolemia in the general population. Our objective was to use a modified version
Externí odkaz:
https://doaj.org/article/2a3efc5dac0641498154a894e87c2f3d