Zobrazeno 1 - 10
of 735
pro vyhledávání: '"R, Lauwerys"'
Autor:
Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-26 (2020)
Abstract Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease characterized by the development of anti-nuclear antibodies. Susceptibility to SLE is multifactorial, with a combination of genetic and environmen
Externí odkaz:
https://doaj.org/article/e20309c0541c416c958c9d60fca43e2b
Autor:
Paraskevi Chairta, Paschalis Nicolaou, Kleitos Sokratous, Christine Galant, Frédéric Houssiau, Anastasis Oulas, George M. Spyrou, Marta E. Alarcon-Riquelme, Bernard R. Lauwerys, Kyproula Christodoulou
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Abstract Background Pathogenesis and aetiology of systemic sclerosis (SSc) are currently unclear, thus rendering disease prognosis, diagnosis and treatment challenging. The aim of this study was to use paired skin biopsy samples from affected and una
Externí odkaz:
https://doaj.org/article/776684f593b243b6ae395cd485ba3138
Autor:
Stéphanie Dierckx, Tatiana Sokolova, Bernard R. Lauwerys, Aleksandra Avramovska, Laurent Meric de Bellefon, Adrien Nzeusseu Toukap, Maria Stoenoiu, Frédéric A. Houssiau, Patrick Durez
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-7 (2020)
Abstract Background/purpose Studies have demonstrated that rheumatoid arthritis (RA) patients who achieve low disease activity or remission are able to taper biological disease-modifying antirheumatic drugs (bDMARDs). The aim of this study was to eva
Externí odkaz:
https://doaj.org/article/8af3ef776b9d4758bbb641d31824b1d7
Autor:
Clement Triaille, Patrick Durez, Tatiana Sokolova, Gaëlle Tilman, Laurent Méric de Bellefon, Christine Galant, Pierre Coulie, Bernard R. Lauwerys, Nisha Limaye
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesOur goal was to assess for the histological and transcriptomic effects of abatacept on RA synovia, and to compare them with previously published data from four other DMARDs: tocilizumab, rituximab, methotrexate, and adalimumab.MethodsSynovi
Externí odkaz:
https://doaj.org/article/f345d21b863d4cfc93703241745468c2
Autor:
Clement Triaille, Louise Vansteenkiste, Manuel Constant, Jérôme Ambroise, Laurent Méric de Bellefon, Adrien Nzeusseu Toukap, Tatiana Sokolova, Christine Galant, Pierre Coulie, Javier Carrasco, Patrick Durez, Bernard R. Lauwerys
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
ObjectivesWe explored histological and transcriptomic profiles of paired synovial biopsies from rheumatoid arthritis (RA) patients, in order to assess homogeneity in synovial tissue at the individual level.MethodsSynovial biopsies were performed simu
Externí odkaz:
https://doaj.org/article/f686b7af319f40c7ab09b966df178446
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9
Autor:
Clément Triaille, Bernard R. Lauwerys
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease targeting the joints. Current treatment strategies are based on clinical, biological and radiological features, yet still fail to reach the goal of early low disease activity in a s
Externí odkaz:
https://doaj.org/article/8de9957c32214eca8727ff0506377db8
Autor:
Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Publikováno v:
eLife, Vol 5 (2016)
Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls produced a comprehensive dataset of the variations causing susceptibility to systemic lupus erythematosus (SLE). Two independent disease association signals in the H
Externí odkaz:
https://doaj.org/article/9cb126754a5c4c41a78ee8db59f27c5a
Autor:
Bernard R Lauwerys, Daniel Hernández-Lobato, Pierre Gramme, Julie Ducreux, Adrien Dessy, Isabelle Focant, Jérôme Ambroise, Bertrand Bearzatto, Adrien Nzeusseu Toukap, Benoît J Van den Eynde, Dirk Elewaut, Jean-Luc Gala, Patrick Durez, Frédéric A Houssiau, Thibault Helleputte, Pierre Dupont
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122104 (2015)
Early diagnosis of rheumatoid arthritis (RA) is an unmet medical need in the field of rheumatology. Previously, we performed high-density transcriptomic studies on synovial biopsies from patients with arthritis, and found that synovial gene expressio
Externí odkaz:
https://doaj.org/article/e5d8c3b13a874ed2b9a29176f3ab8f06
Autor:
R. Lauwerys, Perrine Hoet
Publikováno v:
Occupatinal Neurotoxicology ISBN: 9780429281044
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f515e0f5194986027651fbf6956f6c81
https://doi.org/10.1201/9780429281044-3
https://doi.org/10.1201/9780429281044-3
