Synthesis and Antitumour Evaluation of Tricyclic Indole-2-Carboxamides against Paediatric Brain Cancer Cells.

Autor: John Hamilton A; School of Molecular and Life Sciences, Curtin University, Bentley, WA, 6102, Australia., Lane S; School of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia., Werry EL; School of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney NSW, 2006, Australia., Suri A; Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 60611, USA., Bailey AW; Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 60611, USA., Mercé C; Genomics WA, QEII Campus, Nedlands, WA, 6009, Australia., Kadolsky U; Genomics WA, QEII Campus, Nedlands, WA, 6009, Australia., Payne AD; School of Molecular and Life Sciences, Curtin University, Bentley, WA, 6102, Australia., Kassiou M; School of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia., Treiger Sredni S; Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 60611, USA.; Department of Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60611, USA., Saxena A; Genomics WA, QEII Campus, Nedlands, WA, 6009, Australia., Gunosewoyo H; Curtin Medical School, Faculty of Health Sciences, Curtin University, Bentley, WA, 6102, Australia.

Publikováno v: ChemMedChem [ChemMedChem] 2024 Oct 01; Vol. 19 (19), pp. e202400098. Date of Electronic Publication: 2024 Aug 08.

Genomic Alterations Correlated to Trastuzumab Resistance and Clinical Outcomes in HER2+/HR- Breast Cancers of Patients Living in Northwestern China.

Autor: Gang Ma¹ magang7010@stu.xjtu.edu.cn, Binliang Huo¹, Yanwei Shen¹, Xulong Zhu¹, Chong Cheng¹, Wensheng Li², Wei Cao¹ caowei0e1@163.com, Jianhui Li¹ lijh3192@163.com

Publikováno v: Journal of Cancer. 2024, Vol. 15 Issue 14, p4467-4476. 10p.

Arcuate nucleus transcriptome profiling identifies ankyrin repeat and suppressor of cytokine signalling box-containing protein 4 as a gene regulated by fasting in central nervous system feeding circuits

Autor: J-Y, Li, R, Kuick, R C, Thompson, D E, Misek, Y-M, Lai, Y-Q, Liu, B-X, Chai, S M, Hanash, I, Gantz

Publikováno v: Journal of neuroendocrinology. 17(6)

The arcuate nucleus of the hypothalamus is a primary site for sensing blood borne nutrients and hormonal messengers that reflect caloric status. To identify novel energy homeostatic genes, we examined RNA extracts from the microdissected arcuate nucl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f010a0256108619535f186f6d409bac1
https://pubmed.ncbi.nlm.nih.gov/15929745

Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis

Autor: D S, Rickman, M P, Bobek, D E, Misek, R, Kuick, M, Blaivas, D M, Kurnit, J, Taylor, S M, Hanash

Publikováno v: Cancer research. 61(18)

Astrocytomas are heterogeneous intracranial glial neoplasms ranging from the highly aggressive malignant glioblastoma multiforme (GBM) to the indolent, low-grade pilocytic astrocytoma. We have investigated whether DNA microarrays can identify gene ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5f23ada1abaa87a87a63b3cdc7f92e1
https://pubmed.ncbi.nlm.nih.gov/11559565

Demethylation of repetitive DNA sequences in neuroblastoma

Autor: D, Thoraval, J, Asakawa, K, Wimmer, R, Kuick, B, Lamb, B, Richardson, P, Ambros, T, Glover, S, Hanash

Publikováno v: Genes, chromosomescancer. 17(4)

Altered genomic methylcytosine content has been described for a number of tumor types, including neuroblastoma. However, it remains to be determined for different tumor types whether specific loci or chromosomal regions are affected by a methylation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d6fd5e4fa1ed88de2772acc62f8062e
https://pubmed.ncbi.nlm.nih.gov/8946205