Zobrazeno 1 - 10
of 200
pro vyhledávání: '"R, Krulík"'
Publikováno v:
Ceskoslovenska psychiatrie. 91(3)
The interactions between Ca(2+)-channel blockers (verapamil and gallopamil) and synaptic plasma membranes (SPM) from bovine brain or human lymphocyte and platelet plasma membranes were studied. Changes in binding parameters of [3H]imipramine, [3H]des
Publikováno v:
Ceskoslovenska psychiatrie. 89(5)
Effect of cocaine on binding of 3H-imipramine, 3H-desmethylimipramine, 3H-didesmethylimipramine and 3H-amitriptyline to brain synaptic plasma membranes (SPM) was studied. Binding of methylated tricyclic antidepressants was more affected. Cocaine inhi
Publikováno v:
Ceskoslovenska psychiatrie. 89(2)
Authors summarize knowledge in the field of the high-affinity binding of tricyclic antidepressants on cell membranes within last 12 years. Some ideas about the significance of such binding are stated. Both the data from papers and our knowledge are d
Publikováno v:
Ceskoslovenska psychiatrie. 88(5)
It is supposed that adrenergic and serotonergic receptor systems can play a crucial role in pathophysiology of depressive disorder. The hypothesis are based on changes of levels of serotonin and noradrenaline and on changes of their binding sites dur
Publikováno v:
Czechoslovak medicine. 14(1)
Publikováno v:
Scopus-Elsevier
Binding of four tricyclic antidepressants (TCAs)--imipramine, desipramine, didesmethylimipramine and amitriptyline--on the lipid part of biological membranes was studied. Heterogeneity in partitioning of these drugs in artificial lipid bilayers (lipo
Publikováno v:
Endocrinologia experimentalis. 24(1-2)
The period of elimination of tricyclic antidepressant amitriptyline was studied both in plasma and erythrocytes and the influence of the preparation of blood element samples on the elimination of residual antidepressant was examined. Also the effect
Publikováno v:
Neuropsychobiology. 7:12-16
The steady-state values in rats after a second 14-day period of daily subcutaneous administration of imipramine were the same as during the first period; liver demethylation activity rose for up to 3 days and then returned to normal. The imipramine-b
Publikováno v:
International Pharmacopsychiatry. 15:157-165
After the intraperitoneal administration of 0.5 mEq 134 CsCI . kg -1 to mice, the maximum cesium level in the kidney's, heart, lungs and liver was found in the first hour (T 1/2 13 h), in the muscles after 8 h (T 1/2 180 h), in the brain after 24 h (
Autor:
R. Krulík
Publikováno v:
Beiträge zur Klinik der Tuberkulose und Spezifischen Tuberkulose-Forschung. 126:26-30