Zobrazeno 1 - 10
of 167
pro vyhledávání: '"R, Kotter"'
Autor:
Celine Iswarya Partha Sarathi, Amil Sinha, Amir Rafati Fard, Faheem Bhatti, Tanzil Rujeedawa, Shahzaib Ahmed, Melika Akhbari, Aniqah Bhatti, Aria Nouri, Mark R. Kotter, Benjamin M. Davies, Oliver D. Mowforth
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionDegenerative cervical myelopathy (DCM) is a form of chronic spinal cord injury, with a natural history of potential for progression over time. Whilst driven by mechanical stress on the spinal cord from degenerative and congenital patholog
Externí odkaz:
https://doaj.org/article/79b3b9d937e543ccac1cc0f2b5c778dc
Autor:
Amir Rafati Fard, Oliver D. Mowforth, Melissa Yuan, Samuel Myrtle, Keng Siang Lee, Arka Banerjee, Maaz Khan, Mark R. Kotter, Virginia F.J. Newcombe, Emmanuel A. Stamatakis, Benjamin M. Davies
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104915- (2024)
Summary: Background: Degenerative cervical myelopathy (DCM) is the most common cause of adult spinal cord dysfunction globally. Associated neurological symptoms and signs have historically been explained by pathobiology within the cervical spine. How
Externí odkaz:
https://doaj.org/article/2c1cded99b554ebf809fca2a1701660e
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/3ac1b75d69cd410eb3d5d881f1d7d849
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Maternal immune activation (MIA) is mediated by activation of inflammatory pathways resulting in increased levels of cytokines and chemokines that cross the placental and blood-brain barriers altering fetal neural development. Maternal viral infectio
Externí odkaz:
https://doaj.org/article/d98949c685a0471fb248f2e13073f4b9
Autor:
Vedant Gupta, Marc Paranzino, Talal Alnabelsi, Karam Ayoub, Joshua Eason, Andin Mullis, John R Kotter, Andrew Parks, Levi May, Sethabhisha Nerusu, Chen Dai, Daniel Cleland, Steve Wah Leung, Vincent Leigh Sorrell
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246332 (2021)
ObjectiveThe frequency and implications of an elevated cardiac troponin (4th or 5th generation TnT) in patients outside of the emergency department or presenting with non-cardiac conditions is unclear.MethodsConsecutive patients aged 18 years or olde
Externí odkaz:
https://doaj.org/article/4a2d89703cf94730b13b1787b5c07334
Autor:
Susan Giorgi-Coll, Ana I. Amaral, Peter J. A. Hutchinson, Mark R. Kotter, Keri L. H. Carpenter
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI). In the present study, we tested the hypothesis t
Externí odkaz:
https://doaj.org/article/1e35d43f0d3549c7bfdec73a8e038567
Akademický článek
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Autor:
Lindsay Tetreault, Sukhvinder Kalsi-Ryan, null Benjamin Davies, Laura Nanna-Lohkamp, Philip Garwood, Allan R. Martin, Jefferson R. Wilson, James S. Harrop, James D. Guest, Brian K. Kwon, James Milligan, Alberto Martinez Arizala, Mark R. Kotter, Michael G. Fehlings
Publikováno v:
Global spine journal, vol 12, iss 8
Study Design Narrative Review. Objectives The objective of this review is to provide a stepwise approach to the assessment of patients with potential symptoms of degenerative cervical myelopathy (DCM). Methods N/A Results DCM is an overarching term u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e74d26be0a32b9892eb0c62e1732fa
https://doi.org/10.1177/21925682211072847
https://doi.org/10.1177/21925682211072847
Autor:
Qianxin Wu, Junjing Wu, Kaiser Karim, Xi Chen, Tengyao Wang, Sho Iwama, Stefania Carobbio, Peter Keen, Antonio Vidal-Puig, Mark R. Kotter, Andrew Bassett
Publikováno v:
Molecular Cell. 83:1125-1139.e8
CRISPR activation (CRISPRa) is an important tool to perturb transcription, but its effectiveness varies between target genes. We employ human pluripotent stem cells with thousands of randomly integrated barcoded reporters to assess epigenetic feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0444e83289c6971a45507c12cb3dab3
https://doi.org/10.1016/j.molcel.2023.02.011
https://doi.org/10.1016/j.molcel.2023.02.011
Autor:
Yasir A. Syed, Alexandra Baer, Matthias P. Hofer, Ginez A. González, Jon Rundle, Szymon Myrta, Jeffrey K. Huang, Chao Zhao, Moritz J. Rossner, Matthew W. B. Trotter, Gert Lubec, Robin J. M. Franklin, Mark R. Kotter
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 12, Pp 1918-1934 (2013)
Abstract The increasing effectiveness of new disease‐modifying drugs that suppress disease activity in multiple sclerosis has opened up opportunities for regenerative medicines that enhance remyelination and potentially slow disease progression. Al
Externí odkaz:
https://doaj.org/article/fd413ed2dcbf4765b03c4362314086e9