Zobrazeno 1 - 10
of 465
pro vyhledávání: '"R, Kingston"'
Autor:
Zachary Pengju Lin, Luan N. M. Nguyen, Ben Ouyang, Presley MacMillan, Jessica Ngai, Benjamin R. Kingston, Stefan M. Mladjenovic, Warren C. W. Chan
Publikováno v:
ACS Nano. 16:6080-6092
Nanoparticles need to navigate a complex microenvironment to target cells in solid tumors after extravasation. Diffusion is currently the accepted primary mechanism for nanoparticle distribution in tumors. However, the extracellular matrix can limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab5849dc59b0627eb3189337a656aff
https://doi.org/10.1021/acsnano.1c11578
https://doi.org/10.1021/acsnano.1c11578
Autor:
Ayobami S. Edun, Cody LaFlamme, Samuel R. Kingston, Cynthia M. Furse, Michael A. Scarpulla, Joel B. Harley
Publikováno v:
IEEE Sensors Journal. 22:3484-3492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98052f64a994b2b7cabe839ecb7fec79
https://doi.org/10.1109/jsen.2022.3140922
https://doi.org/10.1109/jsen.2022.3140922
Autor:
Jessica Ngai, Presley MacMillan, Benjamin R. Kingston, Zachary P. Lin, Ben Ouyang, Warren C.W. Chan
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 353
Nanoparticles can reduce cytotoxicity, increase circulation time and increase accumulation in tumours compared to free drug. However, the value of using nanoparticles for carrying small molecules to treat tumours at the cellular level has been poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3cdb9b6e1658c945a8909f72efe92f
https://pubmed.ncbi.nlm.nih.gov/36516899
https://pubmed.ncbi.nlm.nih.gov/36516899
Autor:
Shrey Sindhwani, Zachary P. Lin, Ben Ouyang, Jessica Ngai, Benjamin R. Kingston, Presley MacMillan, Abdullah Muhammad Syed, Warren C. W. Chan
Publikováno v:
ACS Nano. 15:14080-14094
The successful delivery of nanoparticles to solid tumors depends on their ability to pass through blood vessels and into the tumor microenvironment. Here, we discovered a subset of tumor endothelial cells that facilitate nanoparticle transport into s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38d09c859d5c6616457d2e6ff903b7d
https://doi.org/10.1021/acsnano.1c04510
https://doi.org/10.1021/acsnano.1c04510
Autor:
Elena R. Kingston, David P. Bartel
Publikováno v:
RNA
Target-directed microRNA (miRNA) degradation (TDMD), which is mediated by the protein ZSWIM8, plays a widespread role in shaping miRNA abundances across bilateria. Some endogenous small interfering RNAs (siRNAs) of Drosophila cells have target sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e03feaa150f5e049dbe4db79e1919b
https://doi.org/10.1261/rna.078746.121
https://doi.org/10.1261/rna.078746.121
Akademický článek
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Autor:
Samuel R. Kingston, Cody La Flamme, Mashad Uddin Saleh, Hunter Ellis, Evan Benoit, Ayobami Edun, Michael A. Scarpulla, Cynthia Furse, Joel B. Harley
Publikováno v:
Progress In Electromagnetics Research B. 94:105-126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd1beddc0f2131b09e4e534ddf9a807
https://doi.org/10.2528/pierb21071507
https://doi.org/10.2528/pierb21071507
Autor:
Ben Ouyang, Benjamin R. Kingston, Wilson Poon, Yi-Nan Zhang, Zachary P. Lin, Abdullah M. Syed, Julien Couture-Senécal, Warren C. W. Chan
Publikováno v:
Molecular pharmaceutics. 19(6)
The delivery of therapeutic nanoparticles to target cells is critical to their effectiveness. Here we quantified the impact of biological barriers on the delivery of nanoparticles to macrophages in two different tissues. We compared the delivery of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc1ec0f999dd67e829d38c95d383d74
https://pubmed.ncbi.nlm.nih.gov/35319220
https://pubmed.ncbi.nlm.nih.gov/35319220
Autor:
Anthony J. Tavares, Yi-Nan Zhang, Gang Zheng, Warren C. W. Chan, Julien Couture-Senécal, Juan Chen, Zachary P. Lin, Yuwei Zhang, Wilson Poon, Benjamin R. Kingston, Presley MacMillan, Abdullah Muhammad Syed, Ben Ouyang, Michael S. Valic
Publikováno v:
Nature Materials. 19:1362-1371
Nanoparticle delivery to solid tumours over the past ten years has stagnated at a median of 0.7% of the injected dose. Varying nanoparticle designs and strategies have yielded only minor improvements. Here we discovered a dose threshold for improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b178a1492f749fb84c2c22dcef869f76
https://doi.org/10.1038/s41563-020-0755-z
https://doi.org/10.1038/s41563-020-0755-z
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004997 (2015)
Analyses of gene expression profiles in evolutionarily diverse organisms have revealed a role for microRNAs in tuning tissue-specific gene expression. Here, we show that the relatively abundant and constitutively expressed miR-58 family of microRNAs
Externí odkaz:
https://doaj.org/article/55fa6879c73044749b190a94d7a55279