Zobrazeno 1 - 10
of 1 791
pro vyhledávání: '"R, Kemp"'
Autor:
Paul R. Kemp, Jacob M. Bradshaw, Brijmohan Pandya, Daniel Davies, Mary J. Morrell, Amir H. Sam
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Imperial College School of Medicine, London UK, introduced a new curriculum in 2019, with a focus on the GMC outcomes for graduates, and pedagogy best practice. The new curriculum included formative assessments, named engagement a
Externí odkaz:
https://doaj.org/article/dce0b52eed844ec7a3963bb4dd85aaa3
Autor:
Alvin Shrestha, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Christos Rossios, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307268 (2024)
IntroductionUnderstanding genetic contributors to sarcopenia (age-related loss of muscle strength and mass) is key to finding effective therapies. Variants of the bradykinin receptor 2 (BDKRB2) have been linked to athletic and muscle performance. The
Externí odkaz:
https://doaj.org/article/729f9642b39144fe86a84ce912c50d84
Autor:
Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Christos Rossios, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294330 (2023)
BackgroundAgeing is associated with changes in body composition including an overall reduction in muscle mass and a proportionate increase in fat mass. Sarcopenia is characterised by losses in both muscle mass and strength. Body composition and muscl
Externí odkaz:
https://doaj.org/article/c30fb2aff4ea4c5a9943bf38e3bcd800
Autor:
Christos Rossios, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292402 (2023)
BackgroundAngiotensin II (AII), has been suggested to promote muscle loss. Reducing AII synthesis, by inhibiting angiotensin converting enzyme (ACE) activity has been proposed as a method to inhibit muscle loss. The LACE clinical trial was designed t
Externí odkaz:
https://doaj.org/article/8651c39bcec645eeb9cc2a0bb488cd15
Publikováno v:
Socius, Vol 8 (2022)
The authors examine how state policy contexts may have contributed to unfavorable adult health in recent decades, using merged individual-level data from the 1993–2016 Behavioral Risk Factor Surveillance System ( n = 2,166,835) and 15 state-level p
Externí odkaz:
https://doaj.org/article/6824d4589202472f9fc2cd2d7cdd9537
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1321-1335 (2020)
Abstract Background Surgery can lead to significant muscle loss, which increases recovery time and associates with increased mortality. Muscle loss is not uniform, with some patients losing significant muscle mass and others losing relatively little,
Externí odkaz:
https://doaj.org/article/d39f2a9134fc4fa293f0f14109c4f970
Autor:
Debarghya Dutta Banik, Eric D Benfey, Laura E Martin, Kristen E Kay, Gregory C Loney, Amy R Nelson, Zachary C Ahart, Barrett T Kemp, Bailey R Kemp, Ann-Marie Torregrossa, Kathryn F Medler
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008925 (2020)
Taste receptor cells use multiple signaling pathways to detect chemicals in potential food items. These cells are functionally grouped into different types: Type I cells act as support cells and have glial-like properties; Type II cells detect bitter
Externí odkaz:
https://doaj.org/article/b64c3f5f5d00430ba7fd6f274fe93d67
Publikováno v:
Socius, Vol 6 (2020)
The positive association between educational attainment and adult health (“the gradient”) is stronger in some areas of the United States than in others. Explanations for the geographic pattern have not been rigorously investigated. Grounded in a
Externí odkaz:
https://doaj.org/article/32e972e2c34c4b048e9c7f9e61ffc927
Autor:
Martin Connolly, Benjamin E Garfield, Alexi Crosby, Nick W Morrell, Stephen J Wort, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229409 (2020)
The microRNA miR-1 is an important regulator of muscle phenotype including cardiac muscle. Down-regulation of miR-1 has been shown to occur in left ventricular hypertrophy but its contribution to right ventricular hypertrophy in pulmonary arterial hy
Externí odkaz:
https://doaj.org/article/4cf8c450ad9c45908063fa57b1de799d
Autor:
Martin Connolly, Richard Paul, Roser Farre‐Garros, Samantha A. Natanek, Susannah Bloch, Jen Lee, Jose P. Lorenzo, Harnish Patel, Cyrus Cooper, Avan A. Sayer, Stephen J. Wort, Mark Griffiths, Michael I. Polkey, Paul R. Kemp
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 2, Pp 400-416 (2018)
Abstract Background A loss of muscle mass occurs as a consequence of a range of chronic and acute diseases as well as in older age. This wasting results from an imbalance of protein synthesis and degradation with a reduction in synthesis and resistan
Externí odkaz:
https://doaj.org/article/f1d666d7cc9c48b791f9a314e78d03b6