Zobrazeno 1 - 10
of 781
pro vyhledávání: '"R, Keenan"'
Autor:
Wing Fuk Chan, Hannah D. Coughlan, Yunshun Chen, Christine R. Keenan, Gordon K. Smyth, Andrew C. Perkins, Timothy M. Johanson, Rhys S. Allan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Stably silenced genes with methylated CpG at the promoter are refractory to current CRISPR activation systems. Here the authors create a more robust activation system, TETact that recruits DNA-demethylating TET1 with transcriptional activators.
Externí odkaz:
https://doaj.org/article/aa28af5f1a0d4589a6f38a6f04cab4f2
Preventive Medical Care in Psychiatry: A Practical Guide for Clinicians was written for psychiatrists in training and in clinical practice, as well as other health care providers who wish to learn an evidence-based and user-friendly approach to preve
Autor:
Wing Fuk Chan, Hannah D. Coughlan, Jie H. S. Zhou, Christine R. Keenan, Naiara G. Bediaga, Philip D. Hodgkin, Gordon K. Smyth, Timothy M. Johanson, Rhys S. Allan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
During differentiation, chromosome conformation is remodelled to support lineage-specific transcriptional programs. Here, the authors characterise chromosome conformational changes in B lymphocytes as they differentiate into plasma cells, and provide
Externí odkaz:
https://doaj.org/article/7053b41411834244926ee8cb364e2b61
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In the two decades since the invention of laser-based super resolution microscopy this family of technologies has revolutionised the way life is viewed and understood. Its unparalleled resolution, speed, and accessibility makes super resolution imagi
Externí odkaz:
https://doaj.org/article/f14720d126844d92b80680aced871d2b
Autor:
Meina Li, Christine R. Keenan, Guillermo Lopez-Campos, Jonathan E. Mangum, Qianyu Chen, Danica Prodanovic, Yuxiu C. Xia, Shenna Y. Langenbach, Trudi Harris, Vinzenz Hofferek, Gavin E. Reid, Alastair G. Stewart
Publikováno v:
iScience, Vol 12, Iss , Pp 232-246 (2019)
Summary: Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable to interleukins and transforming growth factor β1 (TGF-β1). However, previous efforts to prevent induction of
Externí odkaz:
https://doaj.org/article/e7525d099b3949b8b7a1119709301e77
Autor:
Christine R. Keenan, Michael J. Mlodzianoski, Hannah D. Coughlan, Naiara G. Bediaga, Gaetano Naselli, Erin C. Lucas, Qike Wang, Carolyn A. de Graaf, Douglas J. Hilton, Leonard C. Harrison, Gordon K. Smyth, Kelly L. Rogers, Thomas Boudier, Rhys S. Allan, Timothy M. Johanson
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102161- (2021)
Summary: The proximity pattern and radial distribution of chromosome territories within spherical nuclei are random and non-random, respectively. Whether this distribution pattern is conserved in the partitioned or lobed nuclei of polymorphonuclear c
Externí odkaz:
https://doaj.org/article/4507fe55d6fe45d69a3ecca9fe7b35b9
Autor:
Wing Fuk Chan, Hannah D Coughlan, Michelle Ruhle, Nadia Iannarella, Carolina Alvarado, Joanna R Groom, Christine R Keenan, Andrew J Kueh, Adam K Wheatley, Gordon K Smyth, Rhys S Allan, Timothy M Johanson
Publikováno v:
Immunology & Cell Biology. 101:345-357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea8bc7d36b265e96fee8232b4e47e53
https://doi.org/10.1111/imcb.12626
https://doi.org/10.1111/imcb.12626
Publikováno v:
Qualitative Research in Medicine & Healthcare, Vol 4, Iss 1 (2020)
In this research, we explore the experiences of rural palliative care patients receiving psychosocial support through telehealth. A longitudinal approach considered how experiences vary over time. Three patients with a terminal cancer diagnosis were
Externí odkaz:
https://doaj.org/article/5cbd9f535bc14ca7a7cb1df7c65ef269
Publikováno v:
European Urology Open Science, Vol 19, Iss , Pp e2347- (2020)
Externí odkaz:
https://doaj.org/article/f06401cb128a418aa9f2bcc24443e01a
Autor:
CHARLES R. KEENAN
Publikováno v:
History.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d9397f3335cc379636e033b4740db9
https://doi.org/10.1111/1468-229x.13359
https://doi.org/10.1111/1468-229x.13359