Zobrazeno 1 - 10
of 1 119
pro vyhledávání: '"R, Kano"'
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
Autor:
Sumiyo Watanabe, Kotaro Hayashi, Kazuko Toh, Hyun Jin Kim, Xueying Liu, Hiroyuki Chaya, Shigeto Fukushima, Keisuke Katsushima, Yutaka Kondo, Satoshi Uchida, Satomi Ogura, Takahiro Nomoto, Hiroyasu Takemoto, Horacio Cabral, Hiroaki Kinoh, Hiroyoshi Y. Tanaka, Mitsunobu R. Kano, Yu Matsumoto, Hiroshi Fukuhara, Shunya Uchida, Masaomi Nangaku, Kensuke Osada, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nanoparticle delivery of siRNA has problems with penetration and off target accumulation. Here, the authors report on the development of Y-shaped block catiomers which dynamically wrap around siRNA; demonstrate increased circulation times and deliver
Externí odkaz:
https://doaj.org/article/e56544229bd24572b3344d7cb418ce63
Autor:
Chiharu Morii, Hiroyoshi Y. Tanaka, Yasuhisa Izushi, Natsumi Nakao, Masaya Yamamoto, Hiromi Matsubara, Mitsunobu R. Kano, Aiko Ogawa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
In pulmonary arterial hypertension (PAH), excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) causes vascular medial thickening. Medial thickening is a histopathological hallmark of pulmonary vascular remodeling, the central dise
Externí odkaz:
https://doaj.org/article/24ed040cdf1846b89c7bef4e59734077
Autor:
Hideharu Hagiya, Shiro Hinotsu, Toshihiro Koyama, Yoshito Zamami, Yasuhisa Tatebe, Tomoko Funahashi, Kazuaki Shinomiya, Yoshihisa Kitamura, Toshiaki Sendo, Hiromi Rakugi, Mitsunobu R Kano
Publikováno v:
BMJ Open, Vol 9, Iss 12 (2019)
Objectives Fall-related mortality among older adults is a major public health issue, especially for ageing societies. This study aimed to investigate current trends in fall-related mortality in Japan using nationwide population-based data covering 19
Externí odkaz:
https://doaj.org/article/ef581ed690f64c0b96f808ae3ed8f9f8
Autor:
Yoshito Zamami, Takahiro Niimura, Toshihiro Koyama, Yuta Shigemi, Yuki Izawa-Ishizawa, Mizuki Morita, Ayako Ohshima, Keisaku Harada, Toru Imai, Hiromi Hagiwara, Naoto Okada, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Yutaka Kondo, Koichiro Tsuchiya, Shiro Hinotsu, Mitsunobu R. Kano, Keisuke Ishizawa
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The survival rate of cardiac arrest patients is less than 10%; therefore, development of a therapeutic strategy that improves their prognosis is necessary. Herein, we searched data collected from medical facilities throughout Japan for drugs that imp
Externí odkaz:
https://doaj.org/article/160330fc247d43b59aa3ba90d25cc60b
Publikováno v:
Frontiers in Sociology, Vol 4 (2019)
Social innovation is not only about tangible new products, services, policies, and laws, but also about changes in societal perceptions, values, and norms. In Japan, current policies for older people, including Long-Term Care Insurance, tend to focus
Externí odkaz:
https://doaj.org/article/45ce55979c9642aca0736d75e97472a4
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Makoto Miyagishi, Nobuhiro Nishiyama, Kazunori Kataoka, Li Yang, Ung-il Chung, Ako Matsuhashi, Xueying Liu, Kanjiro Miyata, Yutaka Miura, Shinsuke Ohba, Sayaka Tanaka, Mitsunobu R. Kano, Vivi Kasim, Shourong Wu
PDF file - 57K, YY1 overexpression does not affect the expression of HIF-1α under hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2088bc589cd22e95f57d459555ba8cb3
https://doi.org/10.1158/0008-5472.22394528.v1
https://doi.org/10.1158/0008-5472.22394528.v1
Autor:
Kohei Miyazono, Koichi Sugimoto, Mitsunobu R. Kano, Akiyoshi Komuro, Yasuyuki Morishita, Hironori Matsuyama, Hiroshi I. Suzuki, Kunihiko Kiyono
Supplementary Figure Legends 1-12 from Autophagy Is Activated by TGF-β and Potentiates TGF-β–Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9f3f66ba9b944005e12828eeadcd6a
https://doi.org/10.1158/0008-5472.22379948.v1
https://doi.org/10.1158/0008-5472.22379948.v1