Zobrazeno 1 - 10
of 187
pro vyhledávání: '"R, Jemmerson"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
C M Mueller, R Jemmerson
Publikováno v:
The Journal of Immunology. 157:5329-5338
Most B lymphocytes recognizing the major epitope on the self Ag mouse cytochrome c (CYT) express one particular VH gene (19.1.2) in combination with one of two Vkappa genes (R9 or 2G5). This restriction made it possible to observe changes in the prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1bf5dff21b96b2e9b3b38dbef81af82
https://doi.org/10.4049/jimmunol.157.12.5329
https://doi.org/10.4049/jimmunol.157.12.5329
Publikováno v:
Proceedings of the National Academy of Sciences. 92:12379-12383
Direct evidence is presented in support of the longstanding but unproven hypothesis that B lymphocytes specific for self antigens (Ags) can be used in the immune response to foreign Ags. We show that the B cells in BALB/c mic responding early to pige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c6b61ef1a43440847957eae7eca57a
https://doi.org/10.1073/pnas.92.26.12379
https://doi.org/10.1073/pnas.92.26.12379
Autor:
J G Johnson, R Jemmerson
Publikováno v:
The Journal of Immunology. 148:2682-2689
Resting memory B lymphocytes specific for the model protein Ag cytochrome c have been shown to be susceptible to tolerance induction in in vitro splenic fragment cultures. This induction of nonresponsiveness is dependent upon the strength of the inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa70c5706deb053f22d4f9f28bb0758a
https://doi.org/10.4049/jimmunol.148.9.2682
https://doi.org/10.4049/jimmunol.148.9.2682
Publikováno v:
Journal of Biological Chemistry. 266:2134-2142
To examine if there are common physicochemical features among antibodies binding the same antigenic region of a protein, B cell hybridomas were prepared against the two major antigenic regions on mammalian cytochromes c, and the nucleotide sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3be1d29b27a8a09ce233b7e7658700e8
https://doi.org/10.1016/s0021-9258(18)52220-1
https://doi.org/10.1016/s0021-9258(18)52220-1
Publikováno v:
The Journal of Immunology. 144:1835-1840
Cytochromes c (cyt c) are among the best characterized model Ag because their amino acid sequences and tertiary structures are well defined. One unique aspect of cyt c as an immunogen is its ability to induce autoantibody responses in animal models,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::626d9ce565902312c12c77b58967630e
https://doi.org/10.4049/jimmunol.144.5.1835
https://doi.org/10.4049/jimmunol.144.5.1835
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
The American journal of tropical medicine and hygiene. 61(1)
Immunodominant proteins in the range of 42-45 kD are important for the serodiagnosis of human granulocytic ehrlichiosis (HGE). Antigens from human isolates of the etiologic agent of HGE cultivated in HL-60 cells were used to immunize BALB/c mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8a27d2f068230dc82e114f991d7fb5
https://pubmed.ncbi.nlm.nih.gov/10432075
https://pubmed.ncbi.nlm.nih.gov/10432075
B cell tolerance to a minor, but not to a major, antigenic surface of the self antigen, cytochrome c
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(6)
To study B cell tolerance to the mitochondrial protein cytochrome c (CYT), the B cell response to pigeon CYT (PCC) was examined in mice transgenic for PCC. PCC was coupled to OVA to provide T cell help, since PCC-specific T cells in PCC-transgenic mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bff10bd55a48cbcccc578b038eecb48c
https://pubmed.ncbi.nlm.nih.gov/9743344
https://pubmed.ncbi.nlm.nih.gov/9743344
Publikováno v:
Molecular immunology. 34(12-13)
Previously we reported that, early in the antibody response of BALB/c mice to several cytochromes c (CYT) coupled to ovalbumin (OVA), B cells responding to the self antigen mouse CYT recognized a single site on mouse CYT and were in much higher frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f01fb2c6a8c1aed7cbe9876c976b86a1
https://pubmed.ncbi.nlm.nih.gov/9464520
https://pubmed.ncbi.nlm.nih.gov/9464520