Zobrazeno 1 - 10
of 623
pro vyhledávání: '"R, Jakobsen"'
Autor:
Bao-cun Zhang, Marlene F. Laursen, Lili Hu, Hossein Hazrati, Ryo Narita, Lea S. Jensen, Aida S. Hansen, Jinrong Huang, Yan Zhang, Xiangning Ding, Maimaitili Muyesier, Emil Nilsson, Agnieszka Banasik, Christina Zeiler, Trine H. Mogensen, Anders Etzerodt, Ralf Agger, Mogens Johannsen, Emil Kofod-Olsen, Søren R. Paludan, Martin R. Jakobsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The cGAS-STING pathway plays a crucial role in anti-tumoral responses by activating inflammation and reprogramming the tumour microenvironment. Upon activation, STING traffics from the endoplasmic reticulum (ER) to Golgi, allowing signalling
Externí odkaz:
https://doaj.org/article/d5f211afbe2146aea0d8433928886c3f
Publikováno v:
Vadose Zone Journal, Vol 23, Iss 4, Pp n/a-n/a (2024)
Abstract Few contaminants have been linked to more devastating human health and environmental impacts than carcinogenic arsenic (As). Geogenic As contamination of groundwater used as a drinking water source continues to threaten hundreds of millions
Externí odkaz:
https://doaj.org/article/d8c1b4cd88e64a21881c06fa76c35907
Autor:
Ditte Jaehger, Iulia Diaconu, Anders Laustsen, Tobias W Bjerg, Aida S Hansen, Trine I Jensen, Mette-Louise Trempenau, Kasper M Jensen, Nicolai O Haahr, Marcus N Rosendal, Jonas B Vejlebo, Rasmus O Bak, Martin R Jakobsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/be21790330ad40b3a927b263360bf8a2
Autor:
Lamin B. Cham, Jesper D. Gunst, Mariane H. Schleimann, Giacomo S. Frattari, Miriam Rosas-Umbert, Line K. Vibholm, Renée M. van der Sluis, Martin R. Jakobsen, Rikke Olesen, Lin Lin, Martin Tolstrup, Ole S. Søgaard
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107628- (2023)
Summary: Human plasmacytoid dendritic cells (pDCs) play a central role in initiating and activating host immune responses during infection. To understand how the transcriptome of pDCs is impacted by HIV-1 infection and exogenous stimulation, we isola
Externí odkaz:
https://doaj.org/article/c71981a857e54b519eb37f5423105348
Autor:
Aida S. Hansen, Lea S. Jensen, Kristine R. Gammelgaard, Kristoffer G. Ryttersgaard, Christian Krapp, Jesper Just, Kasper L. Jønsson, Pia B. Jensen, Thomas Boesen, Mogens Johannsen, Anders Etzerodt, Bent W. Deleuran, Martin R. Jakobsen
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract A key phenomenon in cancer is the establishment of a highly immunosuppressive tumour microenvironment (TME). Despite advances in immunotherapy, where the purpose is to induce tumour recognition and hence hereof tumour eradication, the majori
Externí odkaz:
https://doaj.org/article/243433d9b85349ca81ff3bd193a23e6f
Autor:
Ditte Køster, Johanne Hovgaard Egedal, Søren Lomholt, Malene Hvid, Martin R. Jakobsen, Ulf Müller-Ladner, Hermann Eibel, Bent Deleuran, Tue Wenzel Kragstrup, Elena Neumann, Morten Aagaard Nielsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Fibroblast-like synoviocytes (FLS) play an important pathological role in persistent inflammatory joint diseases such as rheumatoid arthritis (RA). These cells have primarily been characterized in the RA synovial membrane. Here we aim to phe
Externí odkaz:
https://doaj.org/article/534b11d35cf043f5b6353f63fbcc17d0
Autor:
Anders Karlsen, Alba Gonzalez-Franquesa, Jens R. Jakobsen, Michael R. Krogsgaard, Manuel Koch, Michael Kjaer, Stefano Schiaffino, Abigail L. Mackey, Atul S. Deshmukh
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103836- (2022)
Summary: Proteomics analysis of skeletal muscle has recently progressed from whole muscle tissue to single myofibers. Here, we further focus on a specific myofiber domain crucial for force transmission from muscle to tendon, the myotendinous junction
Externí odkaz:
https://doaj.org/article/a69c469fe9fe4f3781380a18aacd2443
Autor:
Laura J. Myhill, Sophie Stolzenbach, Helena Mejer, Lukasz Krych, Simon R. Jakobsen, Witold Kot, Kerstin Skovgaard, Nuria Canibe, Peter Nejsum, Dennis S. Nielsen, Stig M. Thamsborg, Andrew R. Williams
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Dietary probiotics may enhance gut health by directly competing with pathogenic agents and through immunostimulatory effects. These properties are recognized in the context of bacterial and viral pathogens, but less is known about interactions with e
Externí odkaz:
https://doaj.org/article/1bb98401c45243d5a25b80568ff3ea19
Autor:
Michal Tamáš, Stanislava Pankratova, Peter Schjerling, Casper Soendenbroe, Ching‐Yan Chloé Yeung, Cristian Pablo Pennisi, Jens R. Jakobsen, Michael R. Krogsgaard, Michael Kjaer, Abigail L. Mackey
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract Insight into the bidirectional signaling between primary human myogenic cells and neurons is lacking. For this purpose, human myogenic cells were derived from the semitendinosus and gracilis muscles of five healthy individuals and co‐cultu
Externí odkaz:
https://doaj.org/article/74cb20f03038431e9c90762e3b383d57
Autor:
Jesper G. Pedersen, Johanne H. Egedal, Thomas A. Packard, Karthiga Thavachelvam, Guorui Xie, Renée Marije van der Sluis, Warner C. Greene, Nadia R. Roan, Martin R. Jakobsen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The chemokine receptor CCR5 is expressed on multiple cell types, including macrophages, dendritic cells, and T cells, and is the major co-receptor used during HIV transmission. Using a standard αCD3/CD28 in vitro stimulation protocol to render CD4+
Externí odkaz:
https://doaj.org/article/645cdc5c0c3440dcb09dfb4688ca1a1b