Zobrazeno 1 - 10
of 2 659
pro vyhledávání: '"R, Jack"'
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricu
Externí odkaz:
https://doaj.org/article/e98a5ea8c19f4da7a4b877bae77a1e08
Autor:
Kevin A. Mazurek, Ph.D., Leland Barnard, Ph.D., Hugo Botha, M.B., Ch.B., Teresa Christianson, Jonathan Graff-Radford, M.D., David T. Jones, M.D., David S. Knopman, M.D., Ronald C. Petersen, M.D., Ph.D., Prashanthi Vemuri, Ph.D., Clifford R. Jack, Jr., M.D., Farwa Ali, M.B.B.S.
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 3, Pp 491- (2024)
Externí odkaz:
https://doaj.org/article/6c58504e92cc4442a4ec4b007fa37d15
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Autor:
Xi Yu, Scott A. Przybelski, Robert I. Reid, Timothy G. Lesnick, Sheelakumari Raghavan, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr., Prashanthi Vemuri
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Age‐related and Alzheimer's disease (AD) dementia–related neurodegeneration impact brain health. While morphometric measures from T1‐weighted scans are established biomarkers, they may be less sensitive to earlier changes.
Externí odkaz:
https://doaj.org/article/68f17f5c04e049068a8e8c8632f60d2c
Autor:
James J. Gugger, Alexa E. Walter, Ramon Diaz‐Arrastia, Juebin Huang, Clifford R. Jack, Robert Reid, Anna M. Kucharska‐Newton, Rebecca F. Gottesman, Andrea L. C. Schneider, Emily L. Johnson
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 342-354 (2024)
Abstract Objective To determine the association between brain MRI abnormalities and incident epilepsy in older adults. Methods Men and women (ages 45–64 years) from the Atherosclerosis Risk in Communities study were followed up from 1987 to 2018 wi
Externí odkaz:
https://doaj.org/article/955e37c497854d68a8eb0696e6932256
Autor:
Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Jr, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci, Jennifer L. Whitwell
Publikováno v:
NeuroImage, Vol 290, Iss , Pp 120564- (2024)
Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) show distinct atrophy and overlapping hypometabolism profiles, but it is unknown how disruptions in structural and functional connectivity compare between these disorders and whethe
Externí odkaz:
https://doaj.org/article/c9523c15658b48e5b201ae474cbd48e7
Autor:
Evan L. Reynolds, Kristen Votruba, Clifford R. Jack, Richard Beare, Robert I. Reid, Gregory M. Preboske, Camille Waseta, Rodica Pop‐Busui, Robert G. Nelson, Brian C. Callaghan, Eva L. Feldman
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 10, Pp 1891-1898 (2023)
Abstract We performed a cross‐sectional study to determine associations between cognition and MRI‐derived brain outcomes, with obesity, diabetes duration, and metabolic risk factors in 51 Pima American Indians with longstanding type 2 diabetes (T
Externí odkaz:
https://doaj.org/article/a9893f84b94643a29c51aee3139dd69a
Autor:
Neha Singh-Reilly, Hugo Botha, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Mary M. Machulda, Jonathan Graff-Radford, Christopher G. Schwarz, Ronald C. Petersen, Val J. Lowe, Clifford R. Jack, Jr, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103639- (2024)
Primary progressive aphasia (PPA) variants present with distinct disruptions in speech-language functions with little known about the interplay between affected and spared regions within the speech-language network and their interaction with other fu
Externí odkaz:
https://doaj.org/article/67ce0fdfcf9a4894abf06efac9019079
Autor:
Dror Shir, Jonathan Graff-Radford, Angela J. Fought, Timothy G. Lesnick, Scott A. Przybelski, Maria Vassilaki, Val J. Lowe, David S. Knopman, Mary M. Machulda, Ronald C. Petersen, Clifford R. Jack, Jr, Michelle M. Mielke, Prashanthi Vemuri
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103634- (2024)
Introduction: AD and CVD, which frequently co-occur, are leading causes of age-related cognitive decline. We assessed how demographic factors, socioeconomic status (SES) as indicated by education and occupation, vascular risk factors, and a range of
Externí odkaz:
https://doaj.org/article/feaeeef564a042beb90734dee33646ca