Zobrazeno 1 - 10
of 1 384
pro vyhledávání: '"R, Horne"'
Autor:
Emily A. Royse, Amanda D. Manzanares, Heqiao Wang, Kevin C. Haudek, Caterina Belle Azzarello, Lydia R. Horne, Daniel L. Druckenbrod, Megan Shiroda, Sol R. Adams, Ennea Fairchild, Shirley Vincent, Steven W. Anderson, Chelsie Romulo
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract There is growing support and interest in postsecondary interdisciplinary environmental education, which integrates concepts and disciplines in addition to providing varied perspectives. There is a need to assess student learning in these pro
Externí odkaz:
https://doaj.org/article/c232820f505347c891fa84613b821370
Autor:
Chelsie Romulo, Bhawani Venkataraman, Susan Caplow, Shamili Ajgaonkar, Craig R. Allen, Aavudai Anandhi, Steven W. Anderson, Caterina Belle Azzarello, Katja Brundiers, Eunice Blavascunas, Jenny M. Dauer, Daniel L. Druckenbrod, Ennea Fairchild, Lydia R. Horne, Kyungsun Lee, Marizvkuru Mwale, John Mischler, Emily Pappo, Nirav S. Patel, Nicole D. Sintov, Carla S. Ramsdell, Shirley G. Vincent
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-17 (2024)
Abstract Growth in the green jobs sector has increased demand for college graduates who are prepared to enter the workforce with interdisciplinary sustainability skills. Simultaneously, scholarly calls for interdisciplinary collaboration in the servi
Externí odkaz:
https://doaj.org/article/36ebb3ed97734172ac2de865d1980c44
Autor:
Shene Chiou, Aysha H Al-Ani, Yi Pan, Komal M Patel, Isabella Y Kong, Lachlan W Whitehead, Amanda Light, Samuel N Young, Marilou Barrios, Callum Sargeant, Pradeep Rajasekhar, Leah Zhu, Anne Hempel, Ann Lin, James A Rickard, Cathrine Hall, Pradnya Gangatirkar, Raymond KH Yip, Wayne Cawthorne, Annette V Jacobsen, Christopher R Horne, Katherine R Martin, Lisa J Ioannidis, Diana S Hansen, Jessica Day, Ian P Wicks, Charity Law, Matthew E Ritchie, Rory Bowden, Joanne M Hildebrand, Lorraine A O’Reilly, John Silke, Lisa Giulino-Roth, Ellen Tsui, Kelly L Rogers, Edwin D Hawkins, Britt Christensen, James M Murphy, André L Samson
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1717-1749 (2024)
Abstract Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion injuries of the kidney, heart and brain. However, precise identification of the ce
Externí odkaz:
https://doaj.org/article/3261c59629e24716b5f237cbc3d2531c
Autor:
Kimberly L. Hallowell, Katarzyna Dembek, Caitlyn R. Horne, Heather K. Knych, Kristen M. Messenger, Lauren V. Schnabel
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Steroid-associated laminitis remains a major concern with use of corticosteroids in horses. Individual case factors such as joint pathology, pre-existing endocrinopathies, or corticosteroid type, dose, and timing influencing steroid-induced laminitis
Externí odkaz:
https://doaj.org/article/33c5605e379c4f0184a7e6df1ad14b62
Autor:
K. Skaare-Fatland, M. Hermann, J. Assmus, M. Hartveit, T. Ruud, R. Horne, R. Drake, K. Drivenes, E. Biringer
Publikováno v:
European Psychiatry, Vol 67, Pp S390-S390 (2024)
Introduction Patients’ beliefs and attitudes about medications play a role in whether they adhere to their medications or not. Knowledge on how beliefs and attitudes about medications can be influenced is therefore important. Objectives The curre
Externí odkaz:
https://doaj.org/article/07f63c42b0cb4d16a4817e2215652f3a
Autor:
Yanxiang Meng, Sarah E. Garnish, Katherine A. Davies, Katrina A. Black, Andrew P. Leis, Christopher R. Horne, Joanne M. Hildebrand, Hanadi Hoblos, Cheree Fitzgibbon, Samuel N. Young, Toby Dite, Laura F. Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E. Czabotar, James M. Murphy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The necroptosis pathway is a lytic, pro-inflammatory mode of cell death that is widely implicated in human disease, including renal, pulmonary, gut and skin inflammatory pathologies. The precise mechanism of the terminal steps in the pathway
Externí odkaz:
https://doaj.org/article/3125421e28064554a4a1522779b6993c
Autor:
Sarah E. Garnish, Katherine R. Martin, Maria Kauppi, Victoria E. Jackson, Rebecca Ambrose, Vik Ven Eng, Shene Chiou, Yanxiang Meng, Daniel Frank, Emma C. Tovey Crutchfield, Komal M. Patel, Annette V. Jacobsen, Georgia K. Atkin-Smith, Ladina Di Rago, Marcel Doerflinger, Christopher R. Horne, Cathrine Hall, Samuel N. Young, Matthew Cook, Vicki Athanasopoulos, Carola G. Vinuesa, Kate E. Lawlor, Ian P. Wicks, Gregor Ebert, Ashley P. Ng, Charlotte A. Slade, Jaclyn S. Pearson, André L. Samson, John Silke, James M. Murphy, Joanne M. Hildebrand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Across the globe, 2-3% of humans carry the p.Ser132Pro single nucleotide polymorphism in MLKL, the terminal effector protein of the inflammatory form of programmed cell death, necroptosis. Here we show that this substitution confers a gain i
Externí odkaz:
https://doaj.org/article/14198b0aa4ad4e93a3c3095f5a9f9cb4
Autor:
Yanxiang Meng, Christopher R. Horne, Andre L. Samson, Laura F. Dagley, Samuel N. Young, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-12 (2022)
Abstract Necroptosis is a caspase-independent, pro-inflammatory mode of programmed cell death which relies on the activation of the terminal effector, MLKL, by the upstream protein kinase RIPK3. To mediate necroptosis, RIPK3 must stably interact with
Externí odkaz:
https://doaj.org/article/cbe0b2a830d34eb4ad810da967695163
Autor:
Bernhard C. Lechtenberg, Marina P. Gehring, Taylor P. Light, Christopher R. Horne, Mike W. Matsumoto, Kalina Hristova, Elena B. Pasquale
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Eph receptor tyrosine kinases and their ephrin ligands mediate cell-cell communication. Here, the authors assess the structure and dynamics of the EphA2 intracellular region and uncover complex effects of phosphorylation within the linker region betw
Externí odkaz:
https://doaj.org/article/4e61813b18fe47238560b7007035a60e
Autor:
Yanxiang Meng, Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Christopher R. Horne, Cindy Luo, Jean-Marc Garnier, Lung-Yu Liang, Angus D. Cowan, Andre L. Samson, Guillaume Lessene, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The pseudokinase MLKL is activated by the upstream kinase RIPK3 in the necroptotic pathway but the structural basis of MLKL activation is not well understood yet. Here, the authors present the crystal structures of the human RIPK3:MLKL complex and hu
Externí odkaz:
https://doaj.org/article/c906a3851c864c11bf414f6e8e863c7b