Zobrazeno 1 - 10
of 185
pro vyhledávání: '"R, Hagman"'
Autor:
Cang Li, Zhengyu Wang, Licheng Yao, Xingyu Lin, Yongping Jian, Yujia Li, Jie Zhang, Jingwei Shao, Phuc D. Tran, James R. Hagman, Meng Cao, Yusheng Cong, Hong-yu Li, Colin R. Goding, Zhi-Xiang Xu, Xuebin Liao, Xiao Miao, Rutao Cui
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Recent development of new immune checkpoint inhibitors has been particularly successfully in cancer treatment, but still the majority patients fail to benefit. Converting resistant tumors to immunotherapy sensitive will provide a significant
Externí odkaz:
https://doaj.org/article/d2b0cc08f5634978acf720d5bf955d80
Autor:
Yapeng Li, Junfeng Gao, Mohammad Kamran, Laura Harmacek, Thomas Danhorn, Sonia M. Leach, Brian P. O’Connor, James R. Hagman, Hua Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Mast cells are critical effectors of allergic inflammation and protection against parasitic infections. Here the authors demonstrate that GATA2 promotes chromatin accessibility at the super-enhancers of mast cell identity genes and primes both typica
Externí odkaz:
https://doaj.org/article/98ed13f7bcd445fca8318b9df4898a0f
Autor:
Giovanny Hernandez, Taylor S. Mills, Jennifer L. Rabe, James S. Chavez, Susan Kuldanek, Gregory Kirkpatrick, Leila Noetzli, Widian K. Jubair, Michelle Zanche, Jason R. Myers, Brett M. Stevens, Courtney J. Fleenor, Biniam Adane, Charles A. Dinarello, John Ashton, Craig T. Jordan, Jorge Di Paola, James R. Hagman, V. Michael Holers, Kristine A. Kuhn, Eric M. Pietras
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Rheumatoid arthritis (RA) is a debilitating autoimmune disease characterized by chronic inflammation and progressive destruction of joint tissue. It is also characterized by aberrant blood phenotypes including anemia and suppressed lymphopoiesis that
Externí odkaz:
https://doaj.org/article/eca59744a0444860b5057f8bf06972fb
Autor:
Xiyuan Bai, An Bai, Michele Tomasicchio, James R. Hagman, Ashley M. Buckle, Arnav Gupta, Vineela Kadiyala, Shaun Bevers, Karina A. Serban, Kevin Kim, Zhihong Feng, Kathrin Spendier, Guy Hagen, Lorelenn Fornis, David E. Griffith, Monika Dzieciatkowska, Robert A. Sandhaus, Anthony N. Gerber, Edward D. Chan
Publikováno v:
The Journal of Immunology. 209:1746-1759
α1-Antitrypsin (AAT), a serine protease inhibitor, is the third most abundant protein in plasma. Although the best-known function of AAT is irreversible inhibition of elastase, AAT is an acute-phase reactant and is increasingly recognized to have a
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Veterinary Internal Medicine, Vol 30, Iss 2, Pp 574-582 (2016)
Background Obese dogs risk poor life quality, creating a need for increased knowledge of metabolism in overweight dogs. Objectives Investigate postprandial metabolic and hormonal responses to a high‐fat mixed‐meal in dogs and responses of lean ve
Externí odkaz:
https://doaj.org/article/ea08022b77c14feca52a9fb306ef4a44
Alpha-1-antitrypsin binds to the glucocorticoid receptor with biological significance in macrophages
Autor:
Xiyuan Bai, An Bai, Michele Tomasicchio, James R. Hagman, Ashley M. Buckle, Arnav Gupta, Vineela Kadiyala, Shaun Bevers, Karina A. Serban, Kevin Kim, Zhihong Feng, Kathrin Spendier, Guy Hagen, Lorelenn Fornis, David E. Griffith, Monika Dzieciatkowska, Robert A. Sandhaus, Anthony N. Gerber, Edward D. Chan
Alpha-1-antitrypsin (AAT), a serine protease inhibitor produced mainly by the liver, is the third most abundant protein in plasma. While a canonical receptor for AAT has not been identified, AAT can be internalized into the cytoplasm and is known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217d47a25fcc83f5cd9d45036d488c80
https://doi.org/10.1101/2022.03.11.483896
https://doi.org/10.1101/2022.03.11.483896
Autor:
James R. Hagman, Tessa Arends, Curtis Laborda, Jennifer R. Knapp, Laura Harmacek, Brian P. O’Connor
Publikováno v:
Immunol Rev
B lymphocytes develop from uncommitted precursors into immunoglobulin (antibody)-producing B cells, a major arm of adaptive immunity. Progression of early progenitors to antibody-expressing cells in the bone marrow is orchestrated by the temporal reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab7cf1da5d3909e347701c96e3b79d4
https://europepmc.org/articles/PMC9351717/
https://europepmc.org/articles/PMC9351717/
Publikováno v:
Swiss Medical Weekly, Vol 136, Iss 1920 (2006)
Externí odkaz:
https://doaj.org/article/498ade4b160c49dc9e9b165559c4ec0f